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Pygopus 2 helps ovarian cancer cells grow by aiding ribosomal RNA production, independent of Wnt signaling.

Overexpression of COX-2 causes early hair loss in mice, but can be prevented with a COX-2 inhibitor.

Cyproterone acetate may cause liver cancer at high doses, but is considered safe at recommended doses for approved uses.

Lysine carboxymethyl cysteinate (LCC) protects skin from UVB damage by activating autophagy.

Ceramide Synthase 4 is crucial for healthy skin barrier function.

Oral contraceptive use may increase the risk of frontal fibrosing alopecia in women with a specific CYP1B1 gene variant.

A specific genetic trait in tumor cells is linked to longer survival without disease in certain lymphoma patients.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

A new method accurately measures clobetasol propionate in hair and skin.

Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.

Cyproterone acetate with estradiol improved women's self-confidence and emotional well-being without a difference between oral or transdermal methods, but younger women preferred the oral method.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.

Finasteride dosages should be adjusted based on CYP3A5 genotype and liver function to avoid side effects.

CCC1 is essential for ion balance and proper plant cell function.

Potential new drugs for treating PCOS were identified.

The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.

Scientists made all eight versions of a compound called cyoctol, but found it's not an anti-androgen and it fully breaks down in the skin.

A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.

Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.

Melatonin stops melanin production after tyrosinase action, with cyclic GMP mimicking this effect.

Cis-UCA can form new compounds without enzymes, and sulphide donors reduce its UVB-induced toxicity in skin cells.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Certain gene variations are found in people with polycystic ovary syndrome.

Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.

The 736T>A mutation in the LIPH gene is common in Japanese people with autosomal recessive woolly hair.

Diphenyl cresyl phosphate has low toxicity but can harm the liver, kidneys, adrenal glands, and testicles at high doses.