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GlossaryCytocompatibility

ability of a material to safely interact with cells

Cytocompatibility refers to the ability of a material to interact with cells without causing harmful effects. In simpler terms, it's about how well a material can coexist with living cells, which is crucial for medical implants, tissue engineering, and other biomedical applications. For instance, when developing a new scalp treatment for alopecia, ensuring the cytocompatibility of the treatment means it won't damage the hair follicles or surrounding skin cells.

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Electrospun Egg White Protein/Polyvinyl Alcohol/Graphene Oxide Fibrous Wound Dressing: Fabrication, Antibacterial, Cytocompatibility and Wound Healing Assay

research Electrospun egg white protein/polyvinyl alcohol/graphene oxide fibrous wound dressing: Fabrication, antibacterial, cytocompatibility and wound healing assay

10 citations , February 2023 in “Colloids and surfaces. A, Physicochemical and engineering aspects”

Adding 1 mg/ml of graphene oxide to egg white protein wound dressings improves antibacterial properties and supports skin repair.

Bioactive Anti-Inflammatory Antibacterial Hemostatic Citrate-Based Dressing With Macrophage Polarization Regulation for Accelerating Wound Healing and Hair Follicle Neogenesis

research Bioactive antiinflammatory antibacterial hemostatic citrate-based dressing with macrophage polarization regulation for accelerating wound healing and hair follicle neogenesis

61 citations , September 2020 in “Bioactive Materials”

A special dressing called FEA-PCEI can speed up wound healing, reduce scars, and help grow new hair follicles, but only at the right dosage.

research A hydrogel-based first-aid tissue adhesive with effective hemostasis and anti-bacteria for trauma emergency management

30 citations , February 2023 in “Biomaterials Research”

The hydrogel works quickly to stop bleeding and prevent infection, making it a promising first-aid bandage.

research Novel ECM Patch Combines Poly(vinyl alcohol), Human Fibroblast-Derived Matrix, and Mesenchymal Stem Cells for Advanced Wound Healing

28 citations , June 2020 in “ACS Biomaterials Science & Engineering”

The new ECM patch greatly improves wound healing and tissue regeneration.

research Chitosan/LiCl composite scaffolds promote skin regeneration in full-thickness loss

24 citations , January 2019 in “Science China Life Sciences”

Chitosan/LiCl composite scaffolds help heal deep skin wounds better.

3D Printing of Skin Equivalents with Hair Follicle Structures and Epidermal-Papillary-Dermal Layers Using Gelatin/Hyaluronic Acid Hydrogels

research 3D Printing of Skin Equivalents with Hair Follicle Structures and Epidermal‐Papillary‐Dermal Layers Using Gelatin/Hyaluronic Acid Hydrogels

18 citations , July 2022 in “Chemistry - an Asian journal”

Scientists created a 3D printed skin that includes hair and layers similar to real skin using a special gel.

research 3D bioprinting of a gelatin-alginate hydrogel for tissue-engineered hair follicle regeneration

15 citations , March 2022 in “Acta Biomaterialia”

The new 3D bioprinting method successfully regenerated hair follicles and shows promise for treating hair loss.

research A facile, biosynthetic design strategy for high-performance multifunctional bacterial cellulose-based dressing

9 citations , June 2022 in “Composites. Part B, Engineering”

The new dressing with silver nanowires and collagen on bacterial cellulose heals wounds effectively with less toxicity and good antibacterial properties.

Homogeneous Silver Nanoparticle Loaded Polydopamine/Polyethyleneimine-Coated Bacterial Cellulose Nanofibers for Wound Dressing

research Homogeneous silver nanoparticle loaded polydopamine/polyethyleneimine-coated bacterial cellulose nanofibers for wound dressing

5 citations , July 2023 in “International journal of biological macromolecules”

The new wound dressing material speeds up healing, fights infection, and outperforms traditional dressings.

research 3D bioprinting of calcium molybdate nanoparticles-containing immunomodulatory bioinks for hair regrowth

3 citations , June 2023 in “Nano today”

A special bioink with nanoparticles helps regrow hair by reducing inflammation and promoting hair growth signals.

Programmable Viscoelastic Hydrogels Exhibit Antimicrobial and Regenerative Properties to Promote Cell Migration, Wound Healing, and Tissue Remodeling

research Programmable viscoelastic hydrogels exhibit antimicrobial and regenerative properties to promote cell migration, wound healing, and tissue remodeling

April 2026 in “Microsystems & Nanoengineering”

HA-gel-dex hydrogels help heal wounds and regenerate tissue effectively.

research Zinc Peroxide-Mediated In Situ Forming Hydrogels for Endogenous Tissue Regeneration

January 2025 in “Biomaterials Research”

The new zinc peroxide hydrogel speeds up wound healing and tissue regeneration effectively.

research Injectable Photocuring Silk Fibroin-Based Hydrogel Constructs Antioxidant Microenvironment for Skin Repair

January 2023

The hydrogel helps skin heal faster and better than a commercial dressing by creating a protective environment and supporting new blood vessel and hair growth.

research Rational design of keratin-based injectable hydrogels for biomedical applications

January 2016 in “Frontiers in Bioengineering and Biotechnology”

Keratin-based hydrogels can be improved for medical use by adding PEG, making them more soluble and adjustable.

research Multifunctional Injectable Hydrogel Loaded with Cerium-Containing Bioactive Glass Nanoparticles for Diabetic Wound Healing

83 citations , May 2021 in “Biomolecules”

The 5/G hydrogel effectively improves diabetic wound healing.

research PULMONARY DELIVERY OF RESVERATROL-LOADED NANOCOMPOSITE MICROPARTICLES TO TREAT LUNG CANCER

1 citations , January 2020

Resveratrol-loaded nanoparticles show promise for lung cancer treatment.

research 4D polycarbonates via stereolithography as scaffolds for soft tissue repair

101 citations , July 2021 in “Nature Communications”

4D polycarbonate scaffolds show promise for soft tissue repair due to their biocompatibility, shape memory, and minimal immune response.

research Fucoidan-derived carbon dots against Enterococcus faecalis biofilm and infected dentinal tubules for the treatment of persistent endodontic infections

61 citations , July 2022 in “Journal of Nanobiotechnology”

Fucoidan-derived carbon dots can effectively treat root canal infections by killing bacteria and are safer than traditional disinfectants.

research A TA/Cu2+ Nanoparticle Enhanced Carboxymethyl Chitosan-Based Hydrogel Dressing with Antioxidant Properties and Promoting Wound Healing

25 citations , January 2024 in “International Journal of Nanomedicine”

The hydrogel is safe, reduces oxidation, and helps heal wounds effectively.

research An injectable photocuring silk fibroin-based hydrogel for constructing an antioxidant microenvironment for skin repair

15 citations , January 2024 in “Journal of Materials Chemistry B”

The hydrogel speeds up wound healing and improves skin repair better than commercial options.

research Impact of Hydroxyapatite on Gelatin/Oxidized Alginate 3D-Printed Cryogel Scaffolds

6 citations , June 2024 in “Gels”

5% hydroxyapatite in scaffolds improves bone tissue formation and mechanical properties.

A Dynamically Crosslinked, Self-Adapting, Injectable Gelatin–Chondroitin Sulfate Hydrogel With Antibacterial and Antioxidant Properties for Treatment of Deep and Irregular Wounds

research A dynamically crosslinked, self-adapting, injectable gelatin–chondroitin sulfate hydrogel with antibacterial and antioxidant properties for treatment of deep and irregular wounds

4 citations , January 2025 in “Journal of Materials Chemistry B”

The hydrogel effectively treats complex wounds by promoting healing and preventing infection.

Injectable Dual-Crosslinked Poly(Oligo(Ethylene Glycol) Methacrylate) Hydrogels Inspired by Mussel Adhesion for Cutaneous Wound Healing and Functional Tissue Regeneration

research Injectable Dual‐Crosslinked Poly(oligo(Ethylene Glycol) Methacrylate) Hydrogels Inspired by Mussel Adhesion for Cutaneous Wound Healing and Functional Tissue Regeneration

October 2025 in “Advanced Healthcare Materials”

The hydrogels improve wound healing and tissue regeneration better than traditional treatments.

research Incorporation of Finasteride-Loaded Microspheres into Personalized Microneedle for Sustained Transdermal Delivery

May 2024 in “Langmuir”

The new microneedle system safely delivers finasteride through the skin to treat hair loss.

Green Fabrication of Seedbed-Like Flammulina Velutipes Polysaccharides-Derived Scaffolds Accelerating Full-Thickness Skin Wound Healing Accompanied by Hair Follicle Regeneration

research Green fabrication of seedbed-like Flammulina velutipes polysaccharides–derived scaffolds accelerating full-thickness skin wound healing accompanied by hair follicle regeneration

14 citations , November 2020 in “International Journal of Biological Macromolecules”

Mushroom-based scaffolds help heal skin wounds and regrow hair.

research Biocompatible ZnO nanoflower-infused chitosan/alginate/PVA composite for accelerated skin regeneration

2 citations , October 2025 in “Journal of Materials Science Materials in Medicine”

The composite speeds up skin healing and is safe for use in wound dressings.

Safety and Biocompatibility of Mupirocin Nanoparticle-Loaded Hydrogel on Burn Wounds in a Rat Model

research Safety and Biocompatibility of Mupirocin Nanoparticle-Loaded Hydrogel on Burn Wound in Rat Model

9 citations , October 2021 in “Biological and Pharmaceutical Bulletin”

Mupirocin nanoparticle-loaded hydrogel is safe and effective for healing burn wounds.

Surface Modification and Endothelialization of Biomaterials as Potential Scaffolds for Vascular Tissue Engineering Applications

research Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications

421 citations , January 2015 in “Chemical Society Reviews”

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

Physicochemical Properties of pH-Sensitive Hydrogels Based on Hydroxyethyl Cellulose–Hyaluronic Acid for Transdermal Delivery Systems for Skin Lesions

research Physicochemical properties of pH-sensitive hydrogels based on hydroxyethyl cellulose–hyaluronic acid and for applications as transdermal delivery systems for skin lesions

118 citations , May 2015 in “European journal of pharmaceutics and biopharmaceutics”

The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.

research Biomedical Applications of Layer‐by‐Layer Self‐Assembly for Cell Encapsulation: Current Status and Future Perspectives

88 citations , December 2018 in “Advanced Healthcare Materials”

Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.