research Nano-Enabled CRISPR-Cas Gene Editing for Cancer Therapeutics
Nanotechnology improves CRISPR-Cas9 delivery for cancer treatment, but challenges remain.
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research Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis
A specific group of immune and skin cells may cause chronic inflammation in atopic dermatitis.
research Dynamic remodeling of skin microbiota during healthy homeostatic and wound repair conditions
Skin bacteria help heal wounds and restore healthy skin.
research Enhancing Cancer Therapy with Hyperthermia: Synergistic Effects with Natural Compounds and Conventional Treatments
Combining hyperthermia with natural compounds and conventional treatments improves cancer therapy effectiveness and reduces side effects.
research The X Factor in Immunity: Sex Differences Shaped by the X Chromosome
Females generally have stronger immune responses than males due to the X chromosome.
research Novel Insights into TSC22D Family Genes in Metabolic Diseases and Cancer
TSC22D genes are key in metabolic diseases and cancer, offering potential as treatment targets.
research JAK-Inhibitors Beyond the Label: Emerging Applications in Dermatology
JAK inhibitors show promise for treating various skin disorders effectively and safely.
research Spatiotemporal regulation of acute wound healing by the NLRP3 inflammasome: dual roles in macrophage-fibroblast chemotaxis and phenotype during wound repair
NLRP3 helps control inflammation and repair in wound healing, making it a potential target for treatment.
research Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity
Stress can cause hair loss and trigger autoimmunity by damaging hair follicle cells.
research A Novel Approach to Pattern Dermal Papilla Spheroids in Dermal–Epidermal Composites Using Non-Adherent Microwell Arrays
The new method may improve skin grafts and hair growth.
research Comparative histomorphometric and transcriptomic analysis reveals potential genetic determinants of pelage variation between hairy and coarse-woolly sheep
Genetic differences in sheep affect wool type, with fat and immune genes influencing hair traits.
research Advances in Innovative Surgical Implant Manufacturing for Hernia Repair and Soft Tissue Reconstruction
Coating surgical meshes with PRP may improve hernia repair outcomes.
research Microbial allies in skin trauma recovery: from immune modulation to engineered probiotic therapeutics
Engineered probiotics can help heal wounds faster, especially in diabetic foot ulcers.
research Interdisciplinarity traditional Chinese medicine microneedles in skin disease treatment: Recent advances and challenges
Combining traditional Chinese medicine with microneedles shows promise for effectively treating skin diseases with fewer side effects.
research Transient skin stretching stimulates immune surveillance and promotes vaccine delivery via hair follicles
Skin stretching can improve vaccine delivery through hair follicles and boost immune response.
research Tertiary Lymphoid Organs at the Center Stage of Skin's Humoral Immunity
The skin can independently form immune responses through special structures, offering new ways to treat skin diseases.
research Revolutionizing psoriasis care: Microneedle innovations in treatment and diagnosis
Microneedles offer a promising, less invasive way to treat and monitor psoriasis.
research Therapeutic potential of stem cell-derived exosomes in hair regeneration: A systematic review
Stem cell-derived exosomes could be a promising new treatment for hair regrowth.
research Single-cell sequencing combined with spatial transcriptomics reveals the characteristics of follicle-targeted inflammation patterns in primary cicatricial alopecia
Specific immune cells and pathways contribute to hair follicle inflammation and hair loss, suggesting potential treatments for lichen planopilaris.
research Dynamic immunomodulatory nanoarchitectonics: Rewiring tissue regenerative microenvironment via intelligent regulation
Nanotechnology can improve tissue healing by controlling immune responses.
research Emerging biomedical engineering strategies for hair follicle regeneration
New engineering methods show promise for regenerating hair follicles using stem cells and advanced technologies.
research Resolution of experimental malaria-associated acute respiratory distress syndrome is Alox12 independent and shows residual inflammation
Resolving malaria-related lung issues doesn't rely on Alox12 and leaves some inflammation.
research Assessment of miR-19b-3p, miR-182-5p, and miR-155-5p expression and its relationship with alopecia areata severity
miR-155-5p can help diagnose and track alopecia areata severity.
research Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin
Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.
research Understanding the Intricate Pathophysiology of Psoriasis and Related Skin Disorders
Psoriasis involves immune and genetic factors, and understanding these can improve treatments.
research Differential Expression of CXCL12 in Human and Mouse Hair: Androgens Induce CXCL12 in Human Dermal Papilla and Dermal Sheath Cup
Targeting CXCL12 may help treat hair loss caused by androgens.
research The Role of Extracellular Vesicles in the Development and Treatment of Psoriasis: Narrative Review
Extracellular vesicles show promise for treating psoriasis by reducing inflammation and skin lesions.
research Intranasal sensitization model of alopecia areata using pertussis toxin as adjuvant
Pertussis toxin may contribute to hair loss in alopecia areata.
research Hydrogel crosslinking modulates macrophages, fibroblasts, and their communication, during wound healing
Softer hydrogels help wounds heal better with less scarring.
research eLife assessment: Decoding the complexity of delayed wound healing following Enterococcus faecalis infection
Enterococcus faecalis delays wound healing by disrupting cell functions and creating an anti-inflammatory environment.