Increased free testosterone can lead to stronger bones and less body fat but also higher risks of prostate cancer, hair loss, spine issues, and high blood pressure.
IL-18 signaling helps mature Tregs move into the thymus.
Skin cells can naturally limit the growth of cancerous changes by balancing cell renewal and differentiation.
S1PR1 helps control inflammation in blood vessel cells by affecting gene activity differently in various cell types and locations.
Neutrophils are key in causing chronic itch in atopic dermatitis, and blocking CXCR3 could reduce this itch.
Hedgehog signaling can create new hair follicles but may also cause tumors.
Activin A promotes ear hair cell development, while follistatin delays it.
Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.
Fgf20 is crucial for hair follicle formation by influencing cell movement and growth.
Arabidopsis Formin 2 stabilizes actin filaments to aid cell-to-cell trafficking.
The study identified a key protein involved in producing underarm odor and found ways to inhibit it.
Sphingosine 1-phosphate helps control mechanical pain.
IL-1 signaling is crucial for hair follicle stem cell growth and wound healing.
Type XVII collagen may help prevent skin aging.
MFN2 mutations cause mitochondrial problems, unusual fat distribution, and low leptin despite high body fat.
Understanding hair follicle communication can help treat hair loss.
Loss of Dnmt3a and Dnmt3b increases aggressive skin tumors by affecting PPAR-γ.
Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.
Smad4 is crucial for muscle repair, especially in aging, by promoting cell growth over differentiation.
ANE syndrome is caused by a mutation in the RBM28 protein that disrupts ribosome assembly.
NuMA-microtubule interactions are vital for proper skin structure formation and function.
ETS2 drives cancer progression in squamous cell carcinoma and is linked to poor patient outcomes.
Hair follicles supply a crucial brain development protein to the brain via platelets.
ERK activation spreads between cells in mouse skin, linked to cell division and influenced by TPA and EGF receptors.
FoxA is crucial for planarian pharynx regeneration.
23 citations
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August 2022 in “JAMA Dermatology” Patients with alopecia areata feel less regret about treatment decisions when they are involved in the decision-making process.
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December 2008 in “Arthritis Care & Research” The decision board effectively helps lupus nephritis patients in Brazil choose treatments by clearly presenting options and side effects.
17 citations
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July 2006 in “The International Journal of Health Planning and Management” Healthcare organizations must seriously focus on strategic decision-making to succeed in a complex market.