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October 2002 in “PubMed” Human hair keratin scaffolds help repair injured muscles by breaking down and activating muscle cell growth.
April 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Older mice heal wounds without scars due to special fibroblasts.
119 citations
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November 1969 in “Journal of Ultrastructure Research” Macrophages help break down collagen around hair follicles during hair growth.
PRP and microneedling are generally safe but can cause rare severe complications.
44 citations
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June 2023 in “Cell Reports” IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
May 2022 in “The Egyptian Journal of Hospital Medicine” Platelet Rich Plasma (PRP) helps in healing wounds and regenerating tissue, so dermatologists are using it more.
May 2022 in “Advances in Cosmetic Surgery” Platelet-rich fibrin helps in healing and rejuvenation but results vary and can take time.
December 2025 in “Eastern Ukrainian Medical Journal” Standardized protocols are crucial for effective use of platelet-rich plasma and fibrin in tissue regeneration.
April 2014 in “The FASEB Journal” Geranium Sibiricum L extract may promote hair growth by increasing growth factors and decreasing inhibitory factors under stress.
24 citations
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December 2016 in “Stem Cell Research & Therapy” P311 helps skin stem cells become myofibroblast-like cells, aiding wound healing.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin heals with scars because only one type of fibroblast is used, not a mix.
September 2011 in “Clinical Biochemistry” Glycoconjugates help heal hair follicles during skin repair.
1 citations
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October 2025 γδ T cells help control tissue scarring and blood vessel growth in response to foreign objects.
April 2020 in “Journal of The American Academy of Dermatology” Microneedling with platelet-rich plasma can cause temporary, painful lymph node swelling in some patients.
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August 2023 in “Frontiers in Immunology” Targeting TRP channels may help reduce excessive scarring.
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February 2016 in “ACS Applied Materials & Interfaces” Technique creates 3D cell spheroids for hair-follicle regeneration.
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July 2024 in “Bioengineering” PRF lysates reduce inflammation in cancer cells and boost immune response in healthy oral cells.
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January 2022 in “Burns and trauma” Skin cell-derived vesicles can help heal skin injuries effectively.
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April 2022 in “PubVet” The cat's skin condition improved significantly with medication, with no relapse.
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January 2025 in “Burns & Trauma” Targeting Midkine can help reduce pain and itching in keloids.
DPC-Exos can help regenerate hair follicles and heal wounds by activating the Wnt/β-catenin pathway.
November 2023 in “npj regenerative medicine” Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
46 citations
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July 2015 in “Wound repair and regeneration” Keloid scars may form due to changes in skin cell characteristics and specific protein signaling.
August 2023 in “Cell Proliferation” Human cells in plasma-derived gels can potentially mimic hair follicle environments, improving hair regeneration therapies.
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February 2007 in “Plastic and Reconstructive Surgery” Keratinocytes show more TGF-β system activity and collagen production as they age, which might affect wound scarring.
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January 2020 in “Journal of Materials Chemistry B” The biofilm enhances skin healing by promoting cell growth and blood vessel formation.
October 2025 in “Cell Proliferation” IL10_ApoEVs improve skin healing and reduce scarring.
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September 2016 in “The American Journal of Dermatopathology” Enlarged sweat gland ducts may indicate scarring hair loss.
October 2024 in “Journal of Cutaneous Immunology and Allergy” Steroid injections improved symptoms and hair regrowth in a woman with a reaction to permanent makeup.