January 2026 in “Therapeutics” SCUBE3 is a potential target for cancer and alopecia treatment but is challenging to target due to its varied roles.
August 2025 in “Current Issues in Molecular Biology” Key pathways like WNT, EGF, FGF, SHH, and BMP regulate poultry feather growth, with BMP inhibiting it.
February 2025 in “International Journal of Molecular Sciences” Maternal melatonin improves offspring hair growth by affecting specific proteins and pathways.
December 2022 in “Laboratory Animal Research” Trichoblastomas in aged house musk shrews show unique features and may involve serum amyloid A in inflammation.
7 citations
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May 2025 in “Journal of Biomedical Science” Keratin 6A increases skin inflammation, suggesting it could be a target for treating certain skin diseases.
166 citations
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September 2011 in “The Journal of Cell Biology” p63 controls Satb1 to help skin develop properly.
5 citations
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April 2023 in “Life” CCCA affects adolescents too, with genetic and environmental links, requiring careful diagnosis.
213 citations
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September 2020 in “Journal of Functional Biomaterials” Bio-based electrospun fibers improve wound healing but face production and regulatory challenges.
122 citations
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December 2022 in “International Journal of Molecular Sciences” Nanoparticles improve skin treatment but need more research on safety and effectiveness.
99 citations
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January 2004 in “Progress in brain research” Neurotrophins are important for hair growth and could help treat hair loss.
98 citations
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April 2003 in “Die Naturwissenschaften”
96 citations
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September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
89 citations
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January 2021 in “Molecules” Biopolymeric composites need advanced properties for better use in medicine and healing.
87 citations
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February 2000 in “Journal of Investigative Dermatology” Stem cells in developing hair follicles move to specific areas as they mature.
81 citations
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February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
81 citations
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September 2009 in “Birth defects research” Different body areas in mice produce different hair types due to interactions between skin layers.
73 citations
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February 2023 in “Polymers” Peptide hydrogels are promising for drug delivery and tissue repair in medicine.
70 citations
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May 2023 in “Molecules” Ginkgo biloba has health benefits but also contains toxic compounds, driving interest in its use in medicine and food.
57 citations
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August 2002 in “American Journal Of Pathology” Cathepsin L deficiency causes hair and skin issues in mice.
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April 2021 in “JCI insight” Blocking JAK3 signaling can reverse hair loss from alopecia areata.
40 citations
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November 2021 in “International Journal of Molecular Sciences” Mutant keratins cause inflammation in Epidermolysis Bullosa Simplex, suggesting targeting them could help treat the disorder.
37 citations
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December 2021 in “Cells” Alopecia areata severity and treatment response are linked to specific cytokine levels.
35 citations
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April 2024 in “Life” Bee venom, fig, and geranium oil can effectively treat skin conditions and are safer alternatives to some conventional drugs.
32 citations
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January 2022 in “International Journal of Molecular Sciences” Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.
31 citations
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August 2022 in “Frontiers in Oncology” Photobiomodulation therapy helps manage cancer treatment side effects but needs more research for optimization.
31 citations
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August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
30 citations
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February 2022 in “Pharmaceutics” 3D bioprinting improves wound healing by precisely creating scaffolds with living cells and biomaterials, but faces challenges like resolution and speed.
30 citations
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May 2019 in “Medicinal Research Reviews” Combining stem cells and targeted treatments can improve muscle and skin healing after cleft repair.
27 citations
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October 2021 in “Frontiers in Cell and Developmental Biology” There might be a specific histone code for cellular quiescence, but more research is needed.
26 citations
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December 2022 in “Molecules” Nanotechnology can improve treatments for skin discoloration.