research Insights into the context-dependent immunological roles of the CXCL12–CXCR4 axis in alopecia
Blocking the CXCL12–CXCR4 axis may help treat hair loss in alopecia.
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research Conditioned medium from human adipose-derived mesenchymal stromal cells can modulate cell migration and morphology of keratinocytes in vitro
MSC-CM can boost skin cell growth and movement, aiding skin repair.
research The Role of PPARβ/δ-Related Lipid Metabolism in High-Altitude Adaptation of Yak Coat Based on Proteomics and Metabolomics
PPARβ/δ helps yaks adapt to high altitudes by regulating lipid metabolism in their coats.
research Role of LncRNA MRPS28 in Secondary Hair Follicle Development of Cashmere Goats
lncRNA MRPS28 regulates hair follicle development in cashmere goats, affecting cashmere quality.
research Hair growth-promoting effects of Stellera chamaejasme L. extract on C57BL/6 mice via induction of anagen phase genes
Stellera chamaejasme L. extract promotes hair growth by activating hair growth genes.
research Exosomes serve as a crucial mediator of epithelial–fibroblast communication during hair follicle morphogenesis in cashmere goats
Exosomes help hair follicle development in cashmere goats.
research Apoptotic cells may drive cell death in hair follicles during their regression cycle
Apoptotic cells help cause hair follicle cell death during regression.
research 840 Early and late matrix progenitors form the terminally differentiated cell layers of the hair follicle
Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.
research Adipose-Derived Stem Cells and Their Secretory Factors for Skin Aging and Hair Loss
Fat-derived stem cells and their secretions show promise for treating skin aging and hair loss.
research Emerging pharmacotherapies and regenerative solutions for promoting hair growth for androgenetic alopecia
New treatments for hair loss show promise but need more testing for effectiveness and safety.
research Potential of mesenchymal stem cell-derived exosomes in the treatment of androgenetic alopecia
Exosomes from stem cells can help regrow hair like minoxidil.
research Engineered Collagen XVII-loaded dissolving microneedle patch for promoting hair regrowth in androgenic alopecia
A dissolving microneedle patch with collagen XVII effectively promotes hair regrowth in androgenic alopecia.
research Deep Hair Phenomics: Implications in Endocrinology, Development, and Aging
A new tool can analyze hair to detect changes due to hormones, genetics, and aging.
research 1344 Novel human 3D skin model for skin aging research
Scientists created a 3D skin model that shows typical signs of aging, which can help in aging research.
research 11 Plasma-Rich Protein and ACell
PRP is a promising, cost-effective treatment for hair loss by stimulating hair growth.
research Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease
The research provided new insights into the genetic factors contributing to hair loss and skin conditions by analyzing individual cells from the human scalp.
research Faculty Opinions recommendation of Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions.
The skin basement membrane is specialized for different tissue interactions, important for hair growth and attachment.
research Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia
Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.
research The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits
ocu-miR-205 affects hair density in Rex rabbits by promoting cell changes that lead to more hair follicles entering resting phases.
research 1454 Identification of Fetuin A as a potential modulator of scar formation
Fetuin A may increase collagen production and promote scarring.
research Conventional and novel stem cell based therapies for androgenic alopecia
Stem cell therapies show potential for treating hair loss with fewer side effects.
research Wound management in hidradenitis suppurativa
LED light helps human hair root cells grow and prevents them from dying by activating specific growth pathways.
research 216 Human hair follicles can “smell”: OR2AT4-mediated hair growth regulation
Human hair follicles have a scent receptor that can influence hair growth.
research P140 Light-emitting diode light regulates the proliferation of human outer root sheath cells via Wnt/β -catenin and ERK pathway
LED light promotes hair growth by stimulating cell proliferation and reducing cell death.
research Our panel of experts highlight the most important research articles across the spectrum of topics relevant to the field of regenarative medicine
Two growth factors, PDGF and FGF2, can potentially be used together to grow enough cells for a hair loss treatment, but their exact function on human cells needs further confirmation.
research A Regulatory Loop between β-Catenin and Extra-cellular Matrix Components during the Proliferative Phase of Cutaneous Wound Healing
ECM components regulate β-Catenin activity, affecting wound healing.
research Hair follicle markers, expression and modulation: Studies on human scalp skin grafts
Activating cAMP and ATP improves hair growth and strength.
research Clinical Snippets
Ferulic acid helps stabilize vitamins C and E for better skin protection from the sun, certain compounds may promote hair growth, atopic dermatitis patients have lower skin defense molecules, older men are more likely to get a type of skin cancer, and a substance called relaxin may prevent age-related skin thickening.
research Induction of hair growth in hair follicle cells and organ cultures upon treatment with 30 kHz frequency inaudible sound via cell proliferation and antiapoptotic effects
Inaudible sound at 30 kHz can boost hair growth and decrease hair loss by promoting cell growth and reducing cell death in hair follicles.
research Establishment and characterization of a canine keratinocyte organoid culture system
A new method to study dog skin diseases using lab-grown skin cells was developed.