research SIDE EFFECTS OF CYCLOSPORINE COMPARED TO TACROLIMUS AMONG YEMENI KIDNEY TRANSPLANT PATIENTS WHO SHARE THE SAME ADJUVANT AGENTS: MYCOPHENOLATE MOFETIL AND PREDNISONE
Tacrolimus is a better option than cyclosporine due to fewer side effects.
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research 138 Characterization of xenobiotic metabolizing enzymes of a reconstructed human epidermal model from adult hair follicles
The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.
research Lugol's solution-induced painless thyroiditis
Lugol's solution can cause thyroid problems if used long-term for non-approved reasons.
research Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.
research Isotope Dilution-Based Targeted and Nontargeted Carbonyl Neurosteroid/Steroid Profiling
Researchers created a new method to measure brain steroids, finding higher levels of certain steroids and changes due to a drug.
research An assessment of (1) cyproterone acetate and (2) ethinyl oestradiol and lynoestrenol (Minilyn) in the treatment of idiopathic hirsutism
Cyproterone acetate can effectively treat idiopathic hirsutism, but ethinyl oestradiol and lynoestrenol may not always reduce hair growth.
research MK-386, an Inhibitor of 5α-Reductase Type 1, Reduces Dihydrotestosterone Concentrations in Serum and Sebum without Affecting Dihydrotestosterone Concentrations in Semen1
MK-386 lowers DHT in blood and skin but not in semen.
research 41701 Efficacy of the Oral JAK1/JAK2 Inhibitor CTP-543 (Deuruxolitinib) in Adult Patients with Moderate to Severe Alopecia Areata: Results from the Multinational Double-Blind, Placebo-Controlled THRIVE-AA1 Phase 3 Trial
CTP-543 effectively promotes hair regrowth in adults with moderate to severe alopecia areata.
research Thallium poisoning and emergency care:research advances
Thallium poisoning is serious, affecting nerves and organs, and is treated by reducing absorption and removing it from the body.
research Targeted Therapy– and Chemotherapy-Associated Skin Toxicities: Systematic Review and Meta-Analysis
Minocycline reduces acne rash, pyridoxine lowers hand-foot syndrome risk, and scalp cooling lessens hair loss from cancer treatments.
research Wedelolactone, a natural coumestan with multiple pharmacological effects
Wedelolactone may help treat inflammation, infections, cancer, bone loss, and organ damage.
research A computational approach to mechanistic and predictive toxicology of pesticides
Pesticides can cause reproductive and adrenal health issues.
research Refinement of Technique in Injection Lipolysis Based on Scientific Studies and Clinical Evaluation
Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.
research Applications of steroid drugs entrapped in cyclodextrins
Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.
research Successful management of minoxidil toxicosis in a dog
A dog fully recovered from minoxidil poisoning after receiving treatment.
research An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 5-alpha-dihydrotestosterone in human serum and plasma
The procedure accurately measures 5-alpha-dihydrotestosterone in blood, useful for standard tests.
research Protective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway
DA-9401 can protect against finasteride-induced reproductive damage in rats.
research Saline extract of Portulaca elatior leaves with photoprotective and antioxidant activities does not show acute oral and dermal toxicity in mice
research Pharmacokinetics, toxicity, and activity of intravenous dextran sulfate in human immunodeficiency virus infection
Dextran sulfate was found to be toxic and ineffective for treating HIV.
research Testosterone metabolite nonessential for androgen effects
The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.
research Neurosteroid allopregnanolone attenuates development of nicotine withdrawal behavior in mice
Allopregnanolone may help prevent nicotine withdrawal symptoms.
research Combination Therapy for Extensive Tumoral Calcinosis in Juvenile Dermatomyositis
A multi-drug treatment can effectively clear extensive calcinosis in juvenile dermatomyositis.
research The protoporphyrin IX dimethyl ester incorporated soy lecithin for photoinactivation of fluconazole-resistant Candida albicans
research Flurandrenolide
research Toxicity assessment of the green Dunaliella salina microalgae
Dunaliella salina microalgae is safe to eat and may boost health.
research Anti - inflammatory, antioxidant and antimicrobial activity of Vitex negundo and Hibiscus rosa-sinensis herbal formulation against oral pathogens
The herbal mix of hibiscus and vitex shows promise for treating autoimmune diseases due to its effectiveness and low toxicity.
research Neoadjuvant therapy with Disitamab vedotin in treating muscle-invasive bladder cancer: A case report
Disitamab vedotin and gemcitabine effectively treated bladder cancer without major side effects.
research Novel Method for the Estimation of Minoxidil and Aminexil in Marketed Formulation
A new accurate method was developed to measure Minoxidil and Aminexil in solutions.
research 28‐Day Repeated Dose Toxicity and Toxicokinetics Study on Dihydroartemisinin (DHA) in SD Rats
High doses of dihydroartemisinin caused reversible liver toxicity in rats, with females more affected than males.