research 307 Dermatologic toxicities associated with chronic gamma-secretase inhibitor treatment for desmoid tumor
Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.
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research No evidence for THAP1/DYT6 variants as disease modifiers in DYT1 dystonia
THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.
research Dihydroartemisinin loaded nanostructured lipid carriers (DHA-NLC): evaluation of pharmacokinetics and tissue distribution after intravenous administration to rats.
DHA-NLC may improve drug delivery and reduce side effects for cancer treatment.
research Evaluation of Serum Ferritin, Creatinine and Liver Enzymes in Patients with ß- thalassemia After Administration of Deferasirox
Deferasirox effectively reduces iron overload in ß-thalassemia patients but may cause some manageable side effects.
research Sebaceous carcinoma arising at a chronic candidiasis skin lesion of a patient with keratitis-ichthyosis-deafness (KID) syndrome
A man with KID syndrome developed a rare cancer in a long-term skin infection.
research Common Topical Medications
The document concludes that various topical medications are effective for skin conditions but often cause skin irritation as a side effect.
research Acneiform eruptions caused by an epidermal growth factor receptor-tyrosine kinase inhibitor ZD 1839
ZD1839, a cancer drug, can cause mild skin rashes that are treatable without stopping the medication.
research Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier
New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.
research Tineas—Superficial Dermatophyte Infections
For hair fungal infections, take oral antifungals; for skin and nail infections, use topical antifungals, and keep affected areas cool and dry.
research Development and Characterization of Thiolated Cyclodextrin-Based Nanoparticles for Topical Delivery of Minoxidil
Thiolated cyclodextrin-based nanoparticles effectively deliver Minoxidil for scalp treatment without causing skin irritation.
research Icariside II inhibits gastric cancer progression by suppressing the Wnt/β-catenin signaling pathway
Icariside II may help treat gastric cancer by stopping tumor growth.
research Evaluation of the efficacy of intervention in the management of AD chronic disease based on the theory of “prevention of the recrudescence of disease”
The ginseng cicada decoction effectively reduces atopic dermatitis symptoms and improves quality of life safely.
research Omega 3 fatty acid-enriched nanoemulsion of thiocolchicoside for transdermal delivery: formulation, characterization and absorption studies
The new formulation improved the skin absorption of the drug Thiocolchicoside.
research Effect of Carbamates on mRNA Encoding Lipid Enzymes in Hamster Flank Organs
Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.
research Beyond Comfortable: A Removable Antibacterial Electroconductive Cellulose Nonwoven Dressing for Accelerated Wound Healing
The new dressing speeds up wound healing by fighting bacteria and boosting natural electric fields.
research Long-term toxicologic and tumorigenesis studies on an oral contraceptive agent in albino rats
research In Vivo and In Vitro Evaluation of PTeCA (1H‐Pyrrole‐2,3,4,5‐Tetracarboxylic Acid) in Hair Matrix as a Marker for Oxidative Cosmetic Treatment
PTeCA is a reliable marker for detecting oxidative hair treatments.
research Trans-Epidermal Elimination Due to Insulin Formulation: Report of a Rare Adverse Effect
Switching insulin brands caused skin lesions in a diabetic woman, resolved by changing to oral medication.
research Solubilizing steroidal drugs by β-cyclodextrin derivatives
Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.
research Disruptors of Androgen Action and Synthesis
Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.
research Isolation and structural identification of a novel minoxidil analogue in an illegal dietary supplement: triaminodil
A new minoxidil-like substance, triaminodil, was found in an illegal hair growth supplement.
research Evaluating cepharanthine analogues as natural drugs against SARS‐CoV‐2
Cepharanthine analogues, especially tetrandrine, show potential for treating COVID-19.
research Ectoin attenuates cortisone‐induced skin issues by suppression GR signaling and the UVB‐induced overexpression of 11β‐HSD1
Ectoin helps prevent cortisone-induced skin problems and supports skin health.
research A mechanism for topical cutaneous calcinosis
Epilation and DHT cause skin calcification by increasing ATP and calcium deposits.
research Effects of Tithonia diversifolia Extract as a Feed Additive on Digestibility and Performance of Hair Lambs
Tithonia diversifolia extract improved digestion but didn't enhance lamb growth.
research Gradient-dependent release of the model drug TRITC-dextran from FITC-labeled BSA hydrogel nanocarriers in the hair follicles of porcine ear skin
The drug was successfully released into hair follicles using nanocarriers.
research New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors
New compounds may help treat prostate issues without affecting androgen receptors.
research In vitro biocompatibility, antibacterial activity, and release behavior of halloysite nanotubes loaded with diclofenac sodium salt incorporated in electrospun soy protein isolate/hydroxyethyl cellulose nanofibers
The nanofibers are safe, release medicine slowly, and kill bacteria, making them good for wound healing.
research Trichomycosis (trichobacteriosis) axillaris
Shaving and applying erythromycin cream and clotrimazole powder effectively treated trichomycosis axillaris.
research 708 SIG-1451: A topical anti-inflammatory new chemical entity for atopic dermatitis (AD)
SIG-1451 could be a promising new treatment for atopic dermatitis.