December 2025 in “Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)” This systematic review evaluated the effects of Botulinum toxin type A (BoNT) on biochemical biomarkers in head and neck chronic conditions associated with inflammation. Nine studies were included, with concerns about bias in six. The most frequently studied biomarker was the calcitonin gene-related peptide (CGRP), followed by serotonin. Significant effects of BoNT were reported in six studies, including decreased plasma levels of CGRP in chronic migraine and trigeminal neuralgia, changes in serotonin levels, and alterations in oxidative stress and inflammatory markers. Despite these findings, the evidence was rated as very low to moderate certainty.
26 citations
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July 2005 in “Optometry and vision science” Botulinum A toxin injections may cause hair loss on the face and loss of eyelashes.
March 2023 in “Clinical Toxicology”
7 citations
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April 2006 in “Experimental Neurology” Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
2 citations
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March 2022 in “Laboratory Animal Research” A mild botulinum toxin injection improved sperm production and movement in aging mice.
10 citations
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January 2024 in “Heliyon” Dexpanthenol helps protect the heart from damage by reducing inflammation and stress.
Onabotulinumtoxin-A effectively treated a painful scalp condition when other treatments failed.
1 citations
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May 2007 in “Emergency medicine news” Dr. Marina Kovalevsky and her daughter were hospitalized for suspected politically motivated thallium poisoning in Moscow.
3 citations
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May 1963 in “Radiology” Thallium poisoning can be identified through radiological signs and treated effectively with B.A.L.
9 citations
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October 2022 in “Nature Communications” The DiLiCre mouse model is an effective tool for precise genome editing using light.
June 2025 in “Fayoum University Medical Journal/Fayoum University Medical Journal ” Minoxidil and botulinum toxin are equally effective for treating female hair loss.
7 citations
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September 1999 in “PubMed” Eating grouper fish liver can cause vitamin A poisoning with severe symptoms.
33 citations
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August 1993 in “FEBS Letters” A new enzyme in rats may help regulate hair growth.
140 citations
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February 2014 in “Neuron” Delta opioid receptors help regulate touch sensation by reducing neurotransmitter release in the spinal cord.
January 2024 in “Scripta Medica” Nanoparticle delivery can reduce side effects of the cancer drug doxorubicin.
15 citations
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April 2020 in “Journal of The American Academy of Dermatology” Botulinum toxin injections may help treat hair loss by blocking harmful secretion in hair follicles.
3 citations
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January 2022 in “Neurotoxicity Research” Botulinum toxin may help reduce stress-related hair loss.
1 citations
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January 1989 in “Carcinogenesis” Dexamethasone reduces inflammation and delays skin cell changes caused by TPA.
March 2026 in “Critical Care Medicine” Hair restoration can cause severe seizures due to combined drug toxicity.
9 citations
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April 2021 in “Evidence-based complementary and alternative medicine” Guilu Erxian Glue may help reduce chemotherapy side effects like weight loss and heart stress.
March 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Minoxidil treatment improves heart defects in a DiGeorge syndrome model.
53 citations
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January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
3 citations
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September 1980 in “Experientia” Dobutamine does not mimic dopamine at therapeutic doses but may at very high concentrations; microfilaments, not microtubules, are important for wound healing in Xenopus embryos.
269 citations
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May 2002 in “Journal of Neuroscience” Stress increases neurosteroids that help prevent seizures.
2 citations
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May 2017 in “Endocrinology, diabetes & metabolism case reports” Lugol's solution can cause thyroid problems if used long-term for non-approved reasons.
April 2020 in “The FASEB Journal” Testosterone increases heart and blood pressure issues in rats with endotoxemia, and stopping testosterone production can reduce these problems.
October 2022 in “The American journal of gastroenterology” Thymoma-associated multiorgan autoimmunity can cause liver damage and affects multiple organs, with limited treatment options and a generally poor prognosis.
3 citations
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June 2018 in “Internal Medicine” Recombinant thrombomodulin can effectively treat severe complications in Cronkhite-Canada syndrome.
53 citations
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June 1983 in “Journal of Investigative Dermatology” The enzyme is crucial for skin cell development and can be activated without proteolytic activation.
February 2012 in “Hospital Pharmacy”