55 citations
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August 2015 in “AAPS PharmSciTech” The cream with orange peel and liquorice extracts may help reduce skin aging.
May 2022 in “Research Square (Research Square)” OBEME effectively enhances wound healing and could be a promising carrier for skin treatments.
March 2024 in “Journal of pharmacy & pharmaceutical sciences” Polymeric microneedles offer a less invasive, long-lasting drug delivery method that improves patient compliance and reduces side effects.
96 citations
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September 2021 in “International Journal of Molecular Sciences” Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.
95 citations
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July 2015 in “European journal of pharmaceutics and biopharmaceutics” Lipid nanoparticles can help deliver drugs through hair follicles but struggle to penetrate deeper skin layers.
68 citations
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March 2002 in “Journal of pharmaceutical sciences” Nonionic liposomes are the best for delivering genes to skin cells.
89 citations
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November 2014 in “International Journal of Nanomedicine” Using nanostructured lipid carriers to deliver spironolactone could improve treatment for hair loss.
87 citations
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September 2016 in “Journal of Controlled Release” Nanoparticles can improve drug delivery to hair follicles but struggle to penetrate deeper skin layers.
16 citations
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November 2019 in “Nanomedicine” Thermoresponsive nanogels show promise for delivering medicine through the skin but need more safety testing and regulatory approval before clinical use.
2 citations
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October 2025 in “Chinese Medicine” Berberine delivery systems improve wound healing by enhancing bioavailability, reducing inflammation, and promoting tissue regeneration.
December 2025 in “International Journal of Pharmaceutics” PLGA-based microneedles show promise for painless, long-term drug delivery but need design and safety improvements.
9 citations
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July 2017 in “Journal of Drug Delivery Science and Technology” Scientists developed a new method to deliver alopecia treatment directly to hair follicles, which could be a promising treatment for hair loss and other hair diseases.
September 2024 in “Journal of the American Academy of Dermatology” Generic topical and transdermal systems usually cause minimal irritation or sensitization.
48 citations
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July 2023 in “Biomedicines” Hydrogel-forming microneedles are promising for safe, efficient, and controlled drug delivery through the skin.
36 citations
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September 2019 in “Journal of Herbal Medicine” Herbal nano-formulations show potential for effective skin delivery but need more research.
31 citations
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September 2014 in “Journal of Pharmaceutical Sciences” Using a special laser can improve how well hair loss treatments get into the skin and hair follicles.
29 citations
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September 2020 in “Polymers” The PCL/PHB blend allows for slower, more controlled curcumin release than individual polymers.
21 citations
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January 2022 in “Biomaterials Science” RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
10 citations
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June 2023 in “Preprints.org” Hydrogel-forming microneedles are a safe and effective method for delivering drugs through the skin.
4 citations
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July 2023 in “Pharmaceutics (Basel)” Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.
October 2025 in “Pharmaceutics” Microneedles improve drug delivery for skin diseases, enhancing treatment effectiveness and patient compliance.
January 2025 in “Expert Opinion on Drug Delivery” Nanocarriers could improve hair loss treatment but need more research for effectiveness and safety.
June 2022 in “Authorea (Authorea)” Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.
14 citations
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November 2018 in “Journal of drug delivery and therapeutics” Ethosomes are effective, safe carriers for delivering drugs through the skin.
39 citations
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August 2017 in “Colloids and Surfaces B: Biointerfaces” 50-nm nanoparticles are better at penetrating skin and targeting hair follicles for drug delivery than 100-nm ones.
7 citations
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January 2022 in “Bioengineering” The formulation with oleic acid may be better for treating male pattern baldness.
1 citations
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January 2022 in “BioMed Research International” Chitosan-decorated nanoparticles can improve skin delivery and reduce side effects of finasteride.
60 citations
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February 1997 in “Journal of Dermatological Science” Liposomes can safely and effectively deliver substances to mouse hair follicles, potentially useful for human hair treatments.
17 citations
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January 2016 in “Journal of Drug Delivery” PEG and keratin scaffolds can effectively deliver protein drugs by controlling release based on pH levels.
15 citations
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November 2020 in “Pharmaceutics” Tofacitinib nanoparticles can safely and effectively treat alopecia areata by targeting hair follicles.