research A review on computer‐aided chemogenomics and drug repositioning for rationalCOVID ‐19 drug discovery
Computer-aided methods can speed up COVID-19 drug discovery and help find new uses for existing drugs.
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120-150 / 1000+ resultsresearch A review on computer‐aided chemogenomics and drug repositioning for rational
research Formulation and optimization of folate-bovine serum albumin-coated ethoniosomes of pterostilbene as a targeted drug delivery system for lung cancer: In vitro and in vivo demonstrations
The new drug delivery system effectively targets lung cancer cells.
research Recent Advances in Peptide Drug Discovery: Novel Strategies and Targeted Protein Degradation
Peptide drugs now target hard-to-reach proteins more effectively and specifically.
research Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning
Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.
research Controversies in off‐label prescriptions in dermatology: the perspective of the patient, the physician, and the pharmaceutical companies
The document concludes that doctors should carefully consider off-label drug use in dermatology and always inform patients, while more research is needed on the safety and effectiveness of such practices.
research Application of big data analytics in minoxidil drug development: a data-driven model for predicting efficacy and side effect risks
The model predicts minoxidil's effectiveness and side effects better than traditional methods.
research Peer Review #3 of "Computational drug repositioning based on side-effects mined from social media (v0.3)"
Reviewers criticized the study's methods and suggested focusing on drug mechanisms instead of repositioning due to social media data quality concerns.
research Peer Review #2 of "Computational drug repositioning based on side-effects mined from social media (v0.1)"
Reviewers suggested the study on finding new drug uses through social media side-effects needs better methods and clearer limitations.
research Peer Review #3 of "Computational drug repositioning based on side-effects mined from social media (v0.2)"
The study improved and was accepted despite initial concerns about data clarity, methodology, and potential overfitting.
research Peer Review #2 of "Computational drug repositioning based on side-effects mined from social media (v0.2)"
The peer review highlighted the need for clearer data handling, questioned the study's validity, and recognized improvements from the original version.
research Peer Review #1 of "Computational drug repositioning based on side-effects mined from social media (v0.1)"
Reviewers criticized the study for its assumptions, social media data collection issues, and lack of comparison to existing methods.
research A review for cell-based screening methods in drug discovery
Cell-based screening methods are useful and cost-effective for drug discovery but have pros and cons.
research Brimonidine Beyond a Single Specialty: Pharmacological Profile, Dermatologic Applications, and Advances in Drug Delivery Systems
Brimonidine is effective for reducing facial redness in skin conditions and has potential for broader dermatological uses.
research The brief overview, antivirus and anti-SARS-CoV-2 activity, quantitative methods, and pharmacokinetics of cepharanthine: a potential small-molecule drug against COVID-19
Cepharanthine shows promise as a COVID-19 treatment.
research Alopecia Management Potential of Rosemary-Based Nanoemulgel Loaded with Metformin: Approach Combining Active Essential Oil and Repurposed Drug
Rosemary-based gel with metformin may effectively treat hair loss like minoxidil.
research Immunohistochemical, pharmacovigilance, and omics analyses reveal the involvement of ATP-sensitive K+ channel subunits in cancers: role in drug–disease interactions
ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.
research Formulation and evaluation of repurposed ketoconazole‐loaded transferosomal gel for enhanced trichogenic effects
The ketoconazole gel improved hair growth and is a promising treatment for hair loss.
research PandaOmics: An AI-Driven Platform for Therapeutic Target and Biomarker Discovery
PandaOmics uses AI to find new disease treatment targets and biomarkers.
research Topical delivery of nanoemulsions for skin cancer treatment
Nanoemulsions can effectively treat skin cancer with fewer side effects.
research Recent Tissue Engineering Approaches to Mimicking the Extracellular Matrix Structure for Skin Regeneration
New materials that better mimic natural skin structure could improve healing, especially for chronic wounds.
research Combinatorial Therapy of Letrozole- and Quercetin-Loaded Spanlastics for Enhanced Cytotoxicity against MCF-7 Breast Cancer Cells
Combining letrozole and quercetin in spanlastics may improve breast cancer treatment.
research Formulation-by-Design of Efinaconazole Spanlastic Nanovesicles for Transungual Delivery Using Statistical Risk Management and Multivariate Analytical Techniques
Spanlastic nanovesicles can improve efinaconazole delivery through nails.
research The Future of Alopecia Treatment: Plant Extracts, Nanocarriers, and 3D Bioprinting in Focus
New treatments like plant extracts, nanocarriers, and 3D bioprinting show promise for hair loss, but more research is needed.
research NANOCARRIER-BASED APPROACHES FOR ENHANCED MANAGEMENT OF ANDROGENETIC ALOPECIA: ADVANCEMENTS AND FUTURE PROSPECTS
Nanocarriers could improve hair loss treatments by delivering drugs directly to hair follicles.
research Rebamipide Induces Hair Regeneration Through EP4-Driven Lipid Metabolism Remodeling
Rebamipide may help regrow hair by activating hair follicle stem cells.
research Structural insights into SARS-CoV-2 spike protein and its natural mutants found in Mexican population
Mutations in the spike protein affect drug binding and effectiveness.
research Metformin and malignant neoplasms: a possible mechanism of antitumor action and prospects for use in practice
Metformin, a diabetes drug, may also help fight cancer, but more research is needed to understand how.
research Industry update: the latest developments in the field of therapeutic delivery, July 2018
New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
research 706 Predictive modeling of patient response to JAK/STAT inhibitors and dynamic patient-matching
Machine learning can predict how well patients with alopecia areata will respond to certain treatments.
research Two years of SARS-CoV-2 infection (2019–2021): structural biology, vaccination, and current global situation
Continued vaccine and drug development is crucial due to new virus variants and regional infection spikes.