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About 50% of 46, XY DSD cases lack a genetic diagnosis, but advanced sequencing methods improve detection.

Complex basal cell carcinomas need personalized treatment due to unique genetic mutations.

scMC effectively separates biological signals from technical noise in single-cell genomics data.

RXRα is crucial for hair growth and skin cell function.

Mice with human-like EGFR had growth issues, skin defects, heart problems, and unusual bone development.

Combining 5α-reductase and aromatase inhibitors may better reduce estrogen levels.

LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.

Regulatory challenges make developing combination therapies in urology difficult and costly.

Y27632 increases cell growth through EGFR signaling, not ROCK1/2.

A new test helps find drugs to treat head and neck cancer by targeting c-Rel.

Introducing the rat OTC gene partially corrected OTC deficiency in mice.

New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.

New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.

Two new gene mutations cause a rare hair disorder.

A specific gene mutation causes long hair in Angora rabbits.

Pyrene excimer nucleic acid probes are promising for detecting biomolecules accurately with potential for biological research and drug screening.

Rat dermal papilla cells have unique genes crucial for hair growth.

Understanding tissue regeneration in animals can improve regenerative medicine.

PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.

Single-cell sequencing can improve livestock health and productivity but faces challenges in precise cell analysis.

The study mapped keratin 15 and 19 genes, aiding future genetic disorder research.

Gene variation affects prostate issues and hair loss.

QR678 and QR678 Neo treatments, combined with corticosteroid injections, work better for alopecia areata than corticosteroid injections alone.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Different PADI isoforms help cells develop diverse functions.

The method accurately and quickly measures silodosin and dutasteride in mixtures.