research Hypothesis: platelet-rich plasma as an adjunct therapy for eczema targeting inflammation, skin barrier repair, and chronic recurrence
Platelet-rich plasma might help treat eczema by reducing inflammation and repairing the skin.
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research SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair
SOX11 and SOX4 help skin cells act like embryonic cells to heal wounds in mice.
research Animal models for the study of fetal tissue repair
Understanding how fetal wounds heal could help improve healing in adults.
research The Spectrum of Scarring in Craniofacial Wound Repair
Wounds on the face usually heal with scars, but understanding how some wounds heal without scars could lead to better treatments.
research Role of stem/progenitor cells in reparative disorders
Adult stem cells are important for tissue repair and have therapeutic potential, but more research is needed to fully use them.
research Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Rescue the Loss of Outer Hair Cells and Repair Cochlear Damage in Cisplatin-Injected Mice
Exosomes from umbilical cord cells fix hearing loss and damaged ear hair cells in mice.
research Effect of decellularisation methods on methacryloyl-substituted placental ECM hydrogels
PlacMA hydrogels from human placenta are versatile and useful for cell culture and tissue engineering.
research Impeding Glial Scarring Hyperplasia and Activating Axon Neogenesis via Immunomodulatory Microneedle Patch for Spinal Cord Repair
A new microneedle patch helps repair spinal cord injuries by reducing scarring and promoting nerve growth.
research Molecular Regulation and Cellular Heterogeneity in Skin Repair and Hair Follicle Regeneration
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
research Diverse mechanisms for endogenous regeneration and repair in mammalian organs
Mammalian organs regenerate using stem cells and cell plasticity, but this ability declines with age.
research Concise Review: The Plasticity of Stem Cell Niches: A General Property Behind Tissue Homeostasis and Repair
Stem cell niches are adaptable and key for tissue maintenance and repair.
research Adipose-derived stem cell exosomes promote critical-sized bone defect repair by enhancing the homing of bone marrow mesenchymal stem cells
Exosomes from fat-derived stem cells help repair large bone defects by attracting and enhancing bone marrow stem cells.
research The Role of Vimentin in Tissue Repair and Cell Growth
Vimentin is crucial for wound healing, cell growth, and managing immune responses.
research Hyaluronic acid (HA)-based hydrogels for full-thickness wound repairing and skin regeneration
Hyaluronic acid-based HA2 hydrogel helps heal skin wounds better with less scarring.
research A regenerative stem cell-derived matrix accelerates functional dermal wound repair in a preclinical diabetic model
A stem cell-derived matrix speeds up healing of diabetic skin wounds.
research Epidermal Notch1 recruits innate lymphoid cells to orchestrate normal skin repair
Notch1 helps skin heal by attracting cells that aid repair.
research Genetically-manipulated adult stem cells as therapeutic agents and gene delivery vehicle for wound repair and regeneration
Genetically-altered adult stem cells can help in wound healing and are becoming crucial in regenerative medicine and drug design.
research Treatment of a Spinal Cord Hemitransection Injury with Keratin Biomaterial Hydrogel Elicits Recovery and Tissue Repair
Keratin hydrogel from human hair helps rats recover better from spinal cord injuries.
research Comparison of the Therapeutic Effect of Allogeneic and Xenogeneic Small Extracellular Vesicles in Soft Tissue Repair
Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
research Microgel emulsion loaded with recombinant oil body as a new drug delivery carrier to promote wound repair
OBEME effectively enhances wound healing and could be a promising carrier for skin treatments.
research In vitro strategies for mimicking dynamic cell–ECM reciprocity in 3D culture models
The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
research Fibroblast heterogeneity: implications for human disease
Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
research Mammalian Fetal Organ Regeneration
Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.
research Traditional Chinese medicine derived exosome-like nanovesicles in wound repair and skin regeneration
TCM-derived nanovesicles show promise for wound healing and skin regeneration but need more research.
research Peimine Promotes Skin Wound Repair in Mice by Activating the Notch1 Signaling Pathway in Fibroblasts
Peimine helps heal skin wounds by activating a specific cell signaling pathway.
research Wound Healing: A Cellular Perspective
The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
research Cellular and molecular mechanisms of repair in acute and chronic wound healing
Acute wounds heal well, but chronic wounds struggle due to ongoing inflammation and poor tissue repair.
research Wound repair at a glance
Wound healing is a complex, multi-phase process involving various cells and activities to repair skin damage.
research Cutaneous wound healing: recruiting developmental pathways for regeneration
Understanding developmental pathways can improve wound healing treatments.
research Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages
Epidermal β-catenin activation changes the dermis by signaling different fibroblast types.