September 2017 in “Journal of Investigative Dermatology” RCS-01 is safe and may help rejuvenate aging skin.
119 citations
,
November 2014 in “Trends in Cell Biology” Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.
8 citations
,
August 2025 in “Journal of Translational Medicine” CD44 signaling can help heal wounds without scars.
6 citations
,
March 2024 in “Experimental Dermatology” Fibrosis causes loss of important fat cells, affecting tissue function.
1 citations
,
March 2024 in “Nanomaterials” Biomimetic scaffolds are better than traditional methods for growing cells and could help regenerate various tissues.
November 2025 in “Journal of Pharmacy and Pharmacology” PEDF reduces oxidative damage and supports stem cells.
54 citations
,
May 2021 in “International Journal of Molecular Sciences” Advances in mechanobiology and immunology could lead to scarless wound healing.
56 citations
,
March 2015 in “Journal of Investigative Dermatology” Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.
14 citations
,
July 2022 in “Nutrients” Vitamin A is important for healthy skin and hair, influencing hair growth and skin healing, but UV light reduces its levels.
11 citations
,
July 2012 in “Experimental dermatology” Innate immunity genes in hair follicle stem cells might have new roles beyond traditional immune functions.
7 citations
,
October 2011 in “BMC Cancer” Overexpression of HDGF in melanocytes does not cause cancer.
August 2025 in “Current Issues in Molecular Biology” Periplaneta americana extract helps hair regrowth in mice with alopecia.
April 2025 in “Journal of Investigative Dermatology” Fibronectin is essential for hair follicle regeneration by supporting stem cells.
April 2021 in “Journal of Investigative Dermatology” Stem cells control their future role by changing ERK signal timing, affecting tissue regeneration and cancer.
5 citations
,
October 2020 in “Frontiers in Cell and Developmental Biology” Reducing FOXA2 in skin cells lowers their ability to grow hair.
21 citations
,
June 2018 in “Current Opinion in Genetics & Development” Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.
207 citations
,
March 2012 in “Development” Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
114 citations
,
August 2002 in “Journal of Investigative Dermatology” Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.
56 citations
,
February 2012 in “Cell Cycle” MicroRNAs are crucial for controlling skin development and healing by regulating genes.
46 citations
,
March 2015 in “Regeneration” Mice can grow new hair follicles after skin wounds through a process not involving existing hair stem cells, but requiring more research to understand fully.
7 citations
,
October 2024 in “Cells” Autophagy is essential for proper skin cell development and function.
169 citations
,
January 2020 in “Burns & Trauma” Platelet-rich plasma speeds up skin wound healing.
122 citations
,
April 2020 in “American Journal Of Pathology” Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
12 citations
,
November 2024 in “Burns & Trauma” Neuroregulation is crucial for skin wound healing and can be targeted to improve recovery.
Bio-nanovesicles could improve hair and skin regeneration by delivering important molecules to repair and heal.
June 2023 in “Frontiers in Bioengineering and Biotechnology” The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
January 2012 in “Elsevier eBooks” New treatments for skin and hair repair show promise, but further improvements are needed.
108 citations
,
July 2002 in “Molecular and cellular biology” Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
Plakophilin 1 helps control skin cell immune responses to prevent excessive inflammation.
172 citations
,
July 2007 in “Journal of Dermatological Science” Stat3 helps skin heal but can also cause skin diseases if overactive.