research Estrogen-Dependent Ontogeny of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus*
Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
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research Chitosan/LiCl composite scaffolds promote skin regeneration in full-thickness loss
Chitosan/LiCl composite scaffolds help heal deep skin wounds better.
research AI-driven biomaterial design: an intelligent closed loop from reverse design to biological response
AI improves biomaterial design by making it faster, cheaper, and more effective for personalized medicine.
research Biomaterials for dermal substitutes
The document concludes that a complete skin restoration biomaterial does not yet exist, and more clinical trials are needed to ensure these therapies are safe and effective.
research Three-dimensional bioprinted hydrogels for the management of diabetic wounds: A review
3D bioprinted hydrogels could improve diabetic wound healing but face challenges like limited blood supply and scalability.
research Application of Platelet-Rich Gel in Repairing Scalp Defects Combined with Skull Exposure: A Case Series Analysis
Platelet-rich gel is an effective treatment for healing scalp wounds with exposed skull.
research Collagen supplementation and regenerative health: advances in biomarker detection and smart material integration
Collagen supplements may improve skin, joints, and recovery, especially with added nutrients.
research Biocompatible nanoparticles and vesicular systems in transdermal drug delivery for various skin diseases
Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.
research Plant cell culture as emerging technology for production of active cosmetic ingredients
Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.
research Studying SARS-CoV-2 infectivity and therapeutic responses with complex organoids
Organoids can help study COVID-19 and develop treatments, but face challenges like instability and limited renewal.
research Skin organoids: A new human model for developmental and translational research
Skin organoids are a promising new model for studying human skin development and testing treatments.
research Immune cell regulation of the hair cycle
Immune cells affect hair growth and could lead to new hair loss treatments.
research Engineering the niche for hair regeneration — A critical review
Further research is needed to improve hair regeneration using stem cells and nanomaterials.
research Accelerated Wound Healing Using Nanoparticles
Nanoparticles can speed up wound healing and deliver drugs effectively but may have potential toxicity risks.
research Diverse cellular players orchestrate regeneration after wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research The role of multiomics in revealing the mechanism of skin repair and regeneration
Multiomics helps understand and improve skin healing and repair.
research Nature-skin-based multi-responsive controlled-release electroactive scaffolds for integrated melanoma postoperative relapse prevention and wound therapy
The scaffold effectively prevents melanoma relapse and aids wound healing.
research Advances in nanomaterial-mediated CRISPR/Cas delivery: from lipid nanoparticles to vesicle-derived systems
Ionizable lipid nanoparticles are the best for delivering gene-editing therapies.
research The global clinical landscape of human-derived extracellular vesicles: an analysis based on ClinicalTrials.gov (2010–2025)
Extracellular vesicles are important for disease treatment and monitoring.
research Liposome-based drug delivery systems for skin wound healing: a promising drug delivery strategy
Liposome-based systems improve skin wound healing effectively.
research Composite materials based on metal-organic frameworks loaded with effective therapeutic components for promoting wound healing
Metal-organic frameworks help heal wounds by effectively delivering medicine.
research Unlocking the Medicinal Potential of Plant-Derived Extracellular Vesicles: current Progress and Future Perspectives
Plant-derived extracellular vesicles show promise for treating diseases like cancer and inflammation.
research Microneedles in Improving Skin Appearance and Enhanced Delivery of Cosmeceuticals
Microneedle technology is effective for skin rejuvenation and enhancing cosmeceutical delivery, with ongoing innovation and increasing commercialization.
research Single-cell analysis of murine fibroblasts identifies neonatal to adult switching that regulates cardiomyocyte maturation
Adult fibroblasts help heart cells mature and improve heart function.
research Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation
Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.
research Chronic Treatment with Minoxidil Induces Elastic Fiber Neosynthesis and Functional Improvement in the Aorta of Aged Mice
Minoxidil treatment increases aorta elasticity and reduces stiffness in aged mice, potentially helping with age-related heart issues.
research Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model
Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
research The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis
Glypican-1 is important for blood vessel growth in hair follicles and could help treat hair loss.
research Development and Evaluation of Alginate–Gelatin Composite Hydrogels via 3D Printing Technology for Pharmaceutical Applications
3D printed alginate-gelatin hydrogels are promising for drug delivery and testing treatments for diseases like Alzheimer's.
research 780 Novel mechanism of UVB-mediated pigmentation through the axis of ATP-P2X7
Scientists discovered a new way UVB light increases skin pigmentation through the ATP-P2X7 pathway.