research Sex differences in steroid levels and steroidogenesis in the nervous system: Physiopathological role
Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.
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research The impact of minoxidil on male reproductive biology: a multi-approach study including systematic review, in vivo, and ex vivo experiments
Minoxidil may harm male reproductive health by causing testicular damage and hormonal disruption.
research 53003 HARNESSING BIOTECHNOLOGICALLY DERIVED ACTIVES FOR SKIN BARRIER RESTORATION IN COMPROMISED SKIN PATIENTS
Natural extracts like kombucha, marine enzymes, and prebiotics can improve and restore damaged skin.
research Adrenal and Gonadal Activity, Androgen Concentrations, and Adult Height Outcomes in Boys With Silver-Russell Syndrome
Higher androgen levels during puberty are linked to shorter adult height in boys with Silver-Russell syndrome.
research The Pathobiology of Skin Aging
Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
research The Fate of Trichohyalin
Trichohyalin is modified by enzymes to form strong structures in hair cells.
research Pharmacologic interventions in aging hair
Minoxidil and Finasteride are effective for male baldness; more research is needed for hair aging treatments.
research Hairless Suppresses Vitamin D Receptor Transactivation in Human Keratinocytes
Hairless protein can block vitamin D activation in skin cells.
research Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice
Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
research A Keratinocyte-specific Epoxygenase, CYP2B12, Metabolizes Arachidonic Acid with Unusual Selectivity, Producing a Single Major Epoxyeicosatrienoic Acid
CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.
research Clinical and hepatic evaluation in adult dengue patients: a prospective two-month cohort study
Dengue symptoms and liver issues can persist for over two months, especially in men.
research Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells
Baricitinib reduces inflammation and improves cell health in premature aging cells.
research Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole‐body energy expenditure
Alkaline ceramidase 1 is crucial for healthy skin and energy balance.
research Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa
Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.
research Responsive Microneedles as a New Platform for Precision Immunotherapy
Microneedles can precisely deliver cancer treatments with fewer side effects.
research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It’s Time to Sound the Alarm
Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
research Back to the Future: From Appendage Development Toward Future Human Hair Follicle Neogenesis
New hair follicles could be created to treat hair loss.
research Pubertal hormones increase hippocampal expression of α4βδ GABAA receptors
Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.
research A role for steroid 5 alpha-reductase 1 in vascular remodeling during endometrial decidualization
The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.
research Antioxidant Capacity and Protective Effect of Cow Placenta Extract on D-Galactose-Induced Skin Aging in Mice
Cow placenta extract has strong antioxidant effects and can delay skin aging in mice.
research A folliculocentric perspective of dandruff pathogenesis: Could a troublesome condition be caused by changes to a natural secretory mechanism?
Dandruff might be caused by changes in how hair follicles naturally release oils and an immune response to this imbalance.
research Aging skin and non-surgical procedures: a basic science overview
Non-surgical procedures can help reduce wrinkles and stimulate skin repair by understanding skin aging at the molecular level.
research Aging of the Human Lip: Current Knowledge and Clinical Implications
Lip aging differs from facial aging, needing specific care for barrier, wrinkles, and pigment changes.
research Excimer Light versus Combination of Tacrolimus and Excimer Light in the Treatment of Alopecia Areata
Combining tacrolimus with excimer light is more effective for treating alopecia areata than using excimer light alone.
research Research advances in smart responsive-hydrogel dressings with potential clinical diabetic wound healing properties
Smart hydrogel dressings could improve diabetic wound healing by adjusting to wound conditions and controlling drug release.
research Past and Future Strategies for GPCR Deorphanization
Finding functions for unknown GPCRs is hard but key for making new drugs.
research Iris germanica L. Rhizome-Derived Exosomes Ameliorated Dihydrotestosterone-Damaged Human Follicle Dermal Papilla Cells Through the Activation of Wnt/β-Catenin Pathway
Iris-exosomes may help treat hair loss by activating hair growth pathways.
research The impact of cannabis use on local anesthetic dosing during hair restoration surgery: a case report, proposed mechanisms, and clinical recommendations
Cannabis users may need higher anesthetic doses during hair restoration surgery.
research Gas-propelled anti-hair follicle aging microneedle patch for the treatment of androgenetic alopecia
A new microneedle patch helps treat hair loss by improving drug delivery to hair follicles.
research Pharmacotherapy for Keloids and Hypertrophic Scars
Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.