PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists created a new 3D skin model from cells of plucked hairs that works like real skin and is easier to get.
January 2014 in “Durham e-Theses (Durham University)” Notch1 helps skin heal by attracting cells that aid repair.
62 citations
,
April 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.
64 citations
,
January 2010 in “The FASEB Journal” Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.
28 citations
,
February 2014 in “PLoS ONE” Epidermal stem cells on a special membrane helped mice regrow full skin with hair and functions.
23 citations
,
July 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicle bulge cells don't help skin regrow after glucocorticoid damage; interfollicular epidermis cells do.
19 citations
,
September 2019 in “EMBO molecular medicine” Blocking TSLP reduces skin inflammation and cell overgrowth in psoriasis.
March 2026 in “Frontiers in Immunology” Regulatory T cells help heal skin wounds by reducing inflammation and promoting tissue repair.
April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sweat gland development involves two unique skin cell programs and a temporary skin environment.
215 citations
,
March 2018 in “Archives of Toxicology” Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
153 citations
,
October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
61 citations
,
September 2008 in “Stem Cells” Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
54 citations
,
January 2016 in “Cell reports” Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.
46 citations
,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
43 citations
,
August 2016 in “International Journal of Nanomedicine” Eupafolin nanoparticles help protect skin cells from damage caused by air pollution.
26 citations
,
July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
13 citations
,
April 2022 in “Frontiers in oncology” Melanoma development can be linked to the breakdown of skin's melanin-producing units.
10 citations
,
October 2015 in “Medicina Clínica (english Edition)” Recombinant human epidermal growth factor is versatile, effective, and safe for long-term skin and mucosal treatments.
9 citations
,
April 2006 in “American Journal of Pathology” SGK3 is essential for proper hair growth and health.
2 citations
,
December 2018 Alopecia frontal fibrosante affects facial vellus hair and can be diagnosed with dermatoscopy.
1 citations
,
August 2024 in “Transgenic Research” Activated β-catenin affects hair growth and skin thickness, and changes are reversible.
October 2025 in “International Journal of Cell and Biomedical Science” hUC-MSC secretome can help regrow hair in cases of hair loss.
January 2012 in “Elsevier eBooks” New treatments for skin and hair repair show promise, but further improvements are needed.
26 citations
,
March 2018 in “Dermatology and Therapy” EPC-CM can reduce skin aging signs by boosting the skin's defense system.
23 citations
,
November 2018 in “Development, Growth & Differentiation” Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
36 citations
,
January 2007 in “Archives of Histology and Cytology” Type IV collagen chains vary in different parts of human skin, with specific patterns linked to melanocytes.
1 citations
,
January 2019 in “Elsevier eBooks” New scaffold materials help heal severe skin wounds and improve skin regeneration.
125 citations
,
September 2019 in “Journal of Clinical Immunology” Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.
2 citations
,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.