research Organic and Biogenic Nanocarriers as Bio-Friendly Systems for Bioactive Compounds’ Delivery: State-of-the Art and Challenges
Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.
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research Large-Scale Plasma Proteomics and Genetic Integration Uncover Novel Biological Pathways in Male Pattern Baldness
New biological pathways and potential treatment targets for male pattern baldness were identified.
research Ex Vivo Assessment of Heat and Humidity Effects on Human Skin and Potential Protection by Kombucha Tea Extract
Kombucha tea extract may protect skin from damage in hot and humid conditions.
research A Novel Marker of Tissue Junctions, Collagen XXII
Collagen XXII is a marker for tissue junctions, aiding in structural integrity and found in muscles, heart, skin, and arthritic joints.
research Hair Growth Defects in Insig-Deficient Mice Caused by Cholesterol Precursor Accumulation and Reversed by Simvastatin
Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.
research Single-Cell RNA Profiling of Human Skin Reveals Age-Related Loss of Dermal Sheath Cells and Their Contribution to a Juvenile Phenotype
Aging reduces dermal sheath cells, affecting youthful skin appearance.
research Comparative aspects of the inner root sheath in adult and developing hairs of mammals in relation to the evolution of hairs
The inner root sheath evolved to help hair grow safely through the skin in mammals.
research When the Circadian Clock Meets the Melanin Pigmentary System
Silencing certain circadian clock genes increases skin pigmentation.
research Skin Development and Disease: A Molecular Perspective
Understanding molecular processes in skin development is key to creating targeted treatments for skin disorders.
research Effect of mesenchymal stem cells versus aloe vera on healing of deep second-degree burn
Aloe vera heals deep second-degree burns faster and better than mesenchymal stem cells.
research The beneficial effects of chick embryo extract preconditioning on hair follicle stem cells: A promising strategy to generate Schwann cells
Chick embryo extract helps rat hair follicle stem cells potentially turn into Schwann cells, important for the nervous system.
research Efficacy and Potential Mechanisms of Naringin in Atopic Dermatitis
Naringin may help treat atopic dermatitis by reducing inflammation and improving the skin barrier.
research Proangiogenic and Collagen-Promoting Effects of a 70% Ethanol Extract of Grateloupia angusta in Cutaneous Wound Models
Grateloupia angusta extract helps heal wounds faster and improve skin repair.
research Screening of Microbial Strains Used to Ferment Dendrobium officinale to Produce Polysaccharides, and Investigation of These Polysaccharides’ Skin Care Effects
Fermenting Dendrobium officinale with Lactobacillus reuteri CCFM8631 increases its skin care benefits.
research Expression and Analysis of TBX3 Gene in the Skin from Three Locations on Dun Mongolian Bider Horse
TBX3 gene affects horse coat color, with higher expression in darker areas.
research Mechanistic perspectives on the dermatologic potential of topical metformin: A scoping review
Topical metformin shows promise for skin treatments but needs more testing for safety and effectiveness.
research Deletion of the Sox21 gene drastically affects hair lipids
Deleting the Sox21 gene changes hair lipid composition and increases cholesterol sulfate levels.
research Transcriptomic Analysis Provides Molecular Insights into Skin Development in Dezhou Donkey Foals
Skin maturation in Dezhou donkey foals involves better barrier function, hair growth, and less collagen production.
research Entdeckung von Autoantigenen bei der Haarverluststörung Alopecia areata: Implikation von posttranslationalen Modifikationen
Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.
research Expression profile analysis of dermal papilla cells mRNA in response to WNT10B treatment
WNT10B affects hair growth by altering gene activity in hair cells.
research The human skin as a hormone target and an endocrine gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research 859 Building a functional niche for hair follicle stem cells
Deleting the CRIF1 gene in mice disrupts skin and hair formation, certain proteins affect hair growth, a new compound may improve skin and hair health, blood cell-derived stem cells can create skin-like structures, and hair follicle stem cells come from embryonic cells needing specific signals for development.
research Molecular Docking Studies and ADME Prediction of Novel Isatin Analogs with Potent Anti-EGFR Activity
Some new isatin compounds could be strong cancer-fighting drugs because they fit well in cancer-related proteins and have good drug-like properties.
research The expanding significance of keratin intermediate filaments in normal and diseased epithelia
Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
research Keratins in health and cancer: more than mere epithelial cell markers
Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
research Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile
There are two types of stem cells in rodent hair follicles, each with different keratin proteins.
research Effects of Minoxidil on Cultured Human Skin Fibroblasts
Minoxidil slows down skin cell growth and may help treat scars and skin conditions.
research Biocomposite nanofiber matrices to support ECM remodeling by human dermal progenitors and enhanced wound closure
The nanofiber scaffolds improved skin wound healing by supporting cell growth and tissue repair.
research Diphlorethohydroxycarmalol, Isolated from Ishige okamurae, Increases Prostaglandin E2through the Expression of Cyclooxygenase-1 and -2 in HaCaT Human Keratinocytes
A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.
research Metabolic and transcriptomic reprogramming during contact inhibition-induced quiescence is mediated by YAP-dependent and YAP-independent mechanisms
Quiescent cells have increased mitochondrial activity and ECM gene expression, but reduced glycolysis.