December 2023 in “Facial Plastic Surgery” Local anesthesia, often with sedation, effectively reduces pain in hair transplant harvesting.
15 citations
,
January 2024 in “Chemical Engineering Journal”
April 2023 in “Journal of Investigative Dermatology” A new pain-measuring system using sensors and AI can effectively detect pain in mice, which may help assess pain in humans and develop treatments.
24 citations
,
June 2018 in “Expert Review of Pharmacoeconomics & Outcomes Research” Microneedle technology is beneficial for drug delivery and could make vaccinations cheaper and more accessible.
September 2025 in “Medical Materials Research” Microneedles offer a painless, precise, and versatile method for drug delivery and disease treatment.
8 citations
,
January 2012 in “Dermatology Research and Practice” New subcision technique with a bent needle and syringe improves ease, effectiveness, and comfort for treating acne scars.
1 citations
,
July 2023 in “Pharmaceutics” New microneedles deliver drugs through the skin accurately and effectively.
2 citations
,
January 2022 in “Journal of the American Academy of Dermatology” Virtual reality can reduce pain during scalp injections.
16 citations
,
November 2018 in “The journal of pain/Journal of pain” 14,15-EET may help reduce poststroke pain by affecting certain brain proteins.
December 2024 in “PubMed”
1 citations
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August 2023 in “Advanced Drug Delivery Reviews” Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
46 citations
,
January 2020 in “Research” Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.
19 citations
,
March 2019 in “International Journal of Dermatology” The tattoo machine method safely delivers an average of 1,175 µg/cm² of medication into the skin.
9 citations
,
March 2024 in “Journal of Biomaterials Applications” Rizatriptan benzoate-loaded dissolving microneedles are effective and convenient for treating acute migraines.
January 2009 in “Journal of musculoskeletal pain” A patient got Herpes zoster after a knee injection, possibly due to the injection's trauma, but more evidence is needed.
Thoracic medial branch block may be a simpler and effective alternative to thoracic vertebroplasty for pain management.
October 2018 in “Annals of Reviews & Research” The new gel provides faster and longer-lasting pain relief than the cream.
99 citations
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August 1998 in “Pain” Blocking GABA(A) receptors increases neuron sensitivity, showing GABA and glycine have different roles in pain.
September 2023 in “Journal of the American Academy of Dermatology” Oral difelikefalin significantly reduces itch in notalgia paresthetica.
September 2024 in “Journal of the American Academy of Dermatology” Most patients prefer clinics that play music during procedures.
January 2026 in “International Journal of Applied Pharmaceutics” Nanoparticle-embedded microneedles improve drug delivery through the skin but face challenges in stability and safety.
The Leniwand device, combining vibration and cold, reduces pain more effectively than vibration alone during hair transplant injections.
2 citations
,
November 2024 in “Aesthetic Surgery Journal” Vibration anesthesia effectively and safely reduces pain during botulinum toxin injections.
June 2026 in “Frontiers in Cell and Developmental Biology” Smaller needles help protect stem cells during injections.
April 2024 in “Skin health and disease” Injecting fillers in the temple can cause serious complications, but the damage can be treated if managed properly.
14 citations
,
March 2022 in “Macromolecular Rapid Communications” Polymer microneedles are a promising, painless alternative to traditional needles for delivering drugs through the skin.
June 2018 in “Journal of Acupuncture and Meridian Studies” New technologies in acupuncture and biosensors show promise for better medical treatments and healing.
August 2018 in “Dermatologic Surgery” January 2010 in “USFEU Scientific Library (Ural State Forest Engineering University)” Grooved microneedles made from hyaluronic acid can deliver drugs into the skin with 98% accuracy.
Adding a zygomaticotemporal nerve block reduces pain more effectively during hair regrowth treatments.