research Sex Hormones and Related Compounds, Including Hormonal Contraceptives
The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.
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research Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor
New hybrid compound found to effectively prevent hair loss.
research Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: A legitimate approach
New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.
research Cyproterone Acetate Quantification in Human Plasma by High-performance Liquid Chromatography Coupled to Atmospheric Pressure Photoionization Tandem Mass Spectrometry
The method accurately measures cyproterone acetate in plasma, showing no significant difference between two formulations.
research Pharmacological basis for clinical use of antiandrogens
Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by blocking male sex hormones.
research A new method for synthesis of finasteride
A new, safer method to make finasteride from progesterone is effective for industrial use.
research [Finasteride--ris of "unintentional doping"].
research Cortexolone 17α-Propionate (Clascoterone) is an Androgen Receptor Antagonist in Dermal Papilla Cells In Vitro
Clascoterone may be an effective topical treatment for hair loss.
research NDA Submission of Vepdegestrant (ARV-471) to U.S. FDA: The Beginning of a New Era of PROTAC Degraders
research Determination of the potency of a novel saw palmetto supercritical CO2 extract (SPSE) for 5α-reductase isoform II inhibition using a cell-free in vitro test system
The new saw palmetto extract effectively inhibits an enzyme linked to prostate enlargement and may be as good as standard treatments.
research Compounded topical finasteride-related AEs
research Leuprolide and estrogen versus oral contraceptive pills for the treatment of hirsutism: a prospective randomized study.
Leuprolide plus estrogen is more effective than oral contraceptives for reducing hirsutism.
research Extracellular Signal-Regulated Kinase Mediates Ebastine-Induced Human Follicle Dermal Papilla Cell Proliferation
Ebastine may promote hair regrowth by increasing cell growth through the ERK pathway.
research Bimatoprost
research Compatibility of Caffeine Clobetasol Propionate Dutasteride Nicotinamide and Progesterone in TrichoFoam™, a Natural Vehicle for Hair Foams.
TrichoFoam™ is a stable option for personalized hair loss treatment with most ingredients remaining effective for 90-180 days.
research 5. Novel anticonvulsant effects of supraphysiological doses of progesterone in hippocampal-kindled mice
High doses of progesterone can reduce seizures in mice.
research Effect of Fenugreek Extract on Testosterone Propionate-Induced Benign Prostatic Hyperplasia
Fenugreek extract may help treat benign prostatic hyperplasia.
research Failure of Topical Estrogen Receptor Agonists and Antagonists to Alter Murine Hair Follicle Cycling
Topical estrogen treatments did not change hair growth in certain mouse strains, questioning previous findings on their role in hair growth control.
research The safety of 52 weeks of oral DHEA therapy for postmenopausal women
Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.
research 13C-NMR study of 4-azasteroids in solution and solid state
4-azasteroids, including finasteride, can inhibit 5α-reductase, helping treat conditions like enlarged prostate and hair loss.
research Progesterone, neurosteroids, and the hormonal basis of catamenial epilepsy
Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.
research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research Phosphodiesterase inhibitors used in androgenic alopecia as a possible risk factor for testicular tumor
research Original article / Article original Counterfeit drugs and pharmaceutical preparations seized from the black market among bodybuilders Médicaments de contrefaçon et préparations pharmaceutiques saisis sur le marché noir parmi les bodybuilders
Counterfeit drugs for bodybuilders often contain incorrect or contaminated ingredients and look like real products.
research A Comparison of the Relative Efficacy of Antiandrogens for the Treatment of Acne in Hyperandrogenic Women
Most antiandrogen treatments effectively reduce acne in hyperandrogenic women, but finasteride is the least effective.
research Treatment of idiopathic facial hirsutism with medroxyprogesterone acetate iontophoresis
Medroxyprogesterone acetate iontophoresis safely and effectively reduces facial hair growth in women.
research ยาฉดไซโปรเทอโรนอะซเตทปลดปลอยนาน ชนดใชนำมนมะพราวผสมตวทำละลายเปนนำกระสายยา Cyproterone Acetate Sustained-Release Injection Using Mixed Coconut Oil/Solvent as Vehicle
Mixed coconut oil/solvent is suitable for cyproterone acetate injections, but more safety checks are needed.
research The Effect of Perinatal Blockade of Androgen Receptors on the Expression of Hypothalamic Estrogen Receptor‐a and Sexual Motivation in Male Rats
Blocking androgen receptors early in life increases estrogen levels and reduces sexual motivation in male rats.
research Opposite effects of dihydrotestosterone and estradiol on apoptosis in the anterior pituitary gland from male rats
research The Use of Anabolic Steroids by Bodybuilders in the State of Sergipe, Brazil
Many bodybuilders in Sergipe, Brazil use anabolic steroids, facing health risks like acne, irritability, and hypertension.