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A 13-year-old boy with Cushing syndrome has high cortisol levels from a pituitary gland issue and underdeveloped sexual characteristics.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.

Higher ꝩ-GCS enzyme levels in PCOS patients may play a role in the disease.

Serum steroid profiling, especially 11-deoxycortisol, helps distinguish between adrenocortical carcinoma and adenoma, considering sex and functional status.

Higher granulysin levels in the blood are linked to more severe hair loss in alopecia areata patients, and these levels decrease after effective treatment.

Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.

Hair testing can detect a single GHB exposure, useful for documenting sexual assault.

TSPO might help treat anxiety and depression.

Testosterone levels are not linked to erectile dysfunction in young and middle-aged men with HIV.

Topical glucocorticoids thin the skin and change collagen structure.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

CT scans can find serious prostate cancer even when PSA levels are low.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

A new, efficient method has been developed to detect darolutamide and thalidomide, drugs used for certain hair loss and prostate cancer treatments, in pharmaceuticals and body fluids.

CEC levels may be a useful marker for predicting prostate cancer progression.

ZD1839, a cancer drug, can cause mild skin rashes that are treatable without stopping the medication.

Testosterone's health effects are complex and not definitively understood.

A woman's rare benign tumor that released both cortisol and testosterone was successfully removed, improving her health.

Calculated testosterone values are reliable for assessing hyperandrogenemia in women, making direct measurement unnecessary.

Increasing TSPO in the brain may help improve memory problems.

Testosterone's muscle-building effects do not require its conversion to DHT.

Girls with prepubertal simple hypertrichosis have higher dihydrotestosterone (DHT) levels.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

A woman's excessive hair growth was linked to a rare case of high testosterone caused by a prolactin-producing pituitary tumor.

Testosterone treatment for older men can have short-term benefits, but long-term risks are unclear, requiring careful evaluation and monitoring.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

LC-MS/MS is essential for accurately detecting pregnanes in pregnant mares.

Beard hair follicles convert testosterone to 5α-dihydrotestosterone most intensively.