research 525 Aptamer-Based Targeted Therapy for wound healing and hair growth promotion
Aptamers can improve wound healing and promote hair growth.
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30-60 / 1000+ resultsresearch Is knowledge about the genetic and epigenetic alterations in melanoma a basis for targeted therapy?
Targeting multiple pathways and understanding genetic mutations are crucial for effective melanoma therapy.
research Recent Advances in Peptide Drug Discovery: Novel Strategies and Targeted Protein Degradation
Peptide drugs now target hard-to-reach proteins more effectively and specifically.
research Recent Advances in Genome-Editing Technology with CRISPR/Cas9 Variants and Stimuli-Responsive Targeting Approaches within Tumor Cells: A Future Perspective of Cancer Management
New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.
research Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry
Multitarget drugs are needed to better treat complex diseases.
research Genosomes: An introspection into transfection, future perspectives and applications
Genosomes are promising for safe and effective gene delivery in therapy.
research PERSPECTIVES FOR USING EXOSOMES FOR TARGET DELIVERY IN HER2-PODITIVE BREAST CANCER
Exosomes show promise for targeted treatment of HER2-positive breast cancer.
research Nano-PROTACs: state of the art and perspectives
Nano-PROTACs could improve drug targeting and delivery by using nanotechnology.
research Precision therapeutics in non-scarring alopecia: a systemic genomic and pathway-based framework for targeted interventions
Personalized treatments for hair loss focus on specific genetic and biological pathways.
research 682 Identification of novel potential therapeutic targets by comparative transcriptomic profiling of physiological and pathological skin wounds ex vivo
Combining certain treatments, including FOL005, may improve healing of difficult wounds.
research Protein degradation: expanding the toolbox to restrain cancer drug resistance
Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
research Targeting receptor–regulator interactions
New treatments for cancer and skin disorders show promise in disrupting harmful cell interactions and promoting hair growth.
research Logic-based modeling and drug repurposing for the prediction of novel therapeutic targets and combination regimens against E2F1-driven melanoma progression
Tadalafil and Finasteride may help treat aggressive melanoma.
research Toll-like receptor-targeted anti-tumor therapies: Advances and challenges
TLR-targeted therapies show promise in cancer treatment by helping destroy tumors.
research 479 Transcriptomics identifies potential novel therapeutic targets in androgenetic alopecia
Found new possible treatments for hair loss.
research Wnt is back in drugmakers' sights, but is it druggable?
Drugmakers are optimistic about targeting the Wnt pathway for new treatments despite past challenges.
research Management of a Refractory EIF3E-RSPO2 Fusion Positive Pilomatrical Cancer Patient with Encyclopedic Tumor Analysis Guided Treatment
Personalized treatment based on detailed tumor analysis successfully managed and reduced the patient's aggressive hair follicle cancer.
research Intelligent nanotherapeutic strategies for the delivery of CRISPR system
Smart delivery methods for CRISPR gene editing are crucial for clinical success.
research Ionizable Coenzyme‐Engineered Lipid/Fiber Microplexes Boost Ribosomal Translation to Improve mRNA Therapy for Degenerative Diseases
New lipid/fiber microplexes improve mRNA therapy for degenerative diseases by enhancing cell function and treatment effectiveness.
research Life Sciences Discovery and Technology Highlights
New technologies show promise in healing wounds, treating cancer, autoimmune diseases, and genetic disorders.
research Non-viral delivery of the CRISPR/Cas system: DNAversusRNAversusRNP
RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
research Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance
Repurposing existing drugs and using micronutrients may effectively target cancer stem cells and improve cancer treatment.
research Editorial: Targeted immunological therapies in dermatology
Targeted immunological therapies offer safer and more effective treatments for skin conditions like eczema and psoriasis.
research Targeting the Hippo/YAP /TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers
Blocking YAP/TAZ could be a new way to treat skin cancer.
research A State-of-the-Art Overview on (Epi)Genomics and Personalized Skin Rejuvenating Strategies
Personalized skin rejuvenation using genomics shows promise but needs more research.
research Nano-Enabled CRISPR-Cas Gene Editing for Cancer Therapeutics
Nanotechnology improves CRISPR-Cas9 delivery for cancer treatment, but challenges remain.
research Transcriptome Analysis Methods: From the Serial Analysis of Gene Expression and Microarray to Sequencing new Generation Methods
RNA-Seq is now the standard for detailed gene expression analysis.
research Newly Developed Targeted Therapies Against the Androgen Receptor in Triple-Negative Breast Cancer: A Review
Targeting androgen receptors shows promise for treating triple-negative breast cancer, but more research is needed.
research Targeted radionuclide therapy for head and neck squamous cell carcinoma: a review
Targeted radionuclide therapy shows promise for improving head and neck cancer treatment but needs more research.
research Targeted delivery of extracellular vesicles: the mechanisms, techniques and therapeutic applications
Engineered extracellular vesicles show promise for targeted therapy but need more research for clinical use.