292 citations
,
April 2024 in “Nature Reviews Disease Primers” Early diagnosis and treatment of PCOS are crucial to reduce health risks and costs.
138 citations
,
August 2020 in “Frontiers in Endocrinology” PCOS affects health and quality of life, with effective treatments available and a need for more research on alternative therapies.
88 citations
,
September 2003 in “Clinical endocrinology” Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.
83 citations
,
August 2018 in “BJOG” Uterine transplants for transgender women are feasible but need more research.
78 citations
,
January 2013 in “Dermatology Online Journal” Hidradenitis suppurativa is linked to various diseases like obesity, depression, arthritis, and Crohn's disease, but often occurs alone.
76 citations
,
October 2016 in “Clinics in dermatology” Sex hormones, especially androgens, play a key role in causing acne.
40 citations
,
March 2014 in “Journal of Family Planning and Reproductive Health Care” PCOS is a common hormonal disorder in women, marked by high androgen levels and often seen in 20% of women via ultrasound.
39 citations
,
September 2015 in “Clinical Therapeutics” Teriflunomide effectively reduces relapse rates and disease progression in multiple sclerosis but is not safe for use during pregnancy.
37 citations
,
February 2023 in “Gut Microbes” Gut bacteria can lower androgen levels in male mice.
36 citations
,
December 2014 in “F1000 prime reports” The document concludes that Hidradenitis suppurativa is often underdiagnosed, lacks definitive treatment, and requires better awareness and management strategies.
31 citations
,
September 2020 in “Clinical endocrinology” Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
25 citations
,
March 2021 in “Australasian Journal of Dermatology” Ustekinumab successfully treated a man's resistant skin condition when other treatments failed.
24 citations
,
January 2011 in “Sexual Development” Intersex frogs have different brain gene activity related to sex and thyroid hormones.
19 citations
,
November 2021 in “Reviews in endocrine and metabolic disorders” Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.
7 citations
,
August 2023 in “Life” Extracellular vesicles could help tailor drug treatments, but more research is needed.
7 citations
,
May 2023 in “Nanomaterials” Titanium dioxide nanoparticles may harm the male reproductive system.
6 citations
,
January 2001 in “Cambridge University Press eBooks” PCOS can cause excess hair growth, oily skin, hair loss, acne, and dark skin patches.
5 citations
,
February 2023 in “Journal of Clinical Medicine” Diagnosing and treating PCOS in teenagers is difficult, and the focus is on lifestyle changes and medication to improve health and prevent future issues.
5 citations
,
June 2018 in “Journal of Diabetes, Metabolic Disorders & Control” Women with PCOS may have higher bad cholesterol and are at risk for blood sugar issues; lifestyle changes are recommended.
4 citations
,
August 2021 in “Clinical and Experimental Reproductive Medicine” The 2018 guideline for PCOS suggests new diagnostic criteria and treatments, but recognizes the need for more research.
2 citations
,
November 2021 in “International Journal of Current Pharmaceutical Research” Diagnose and treat hirsutism with oral contraceptives and laser hair removal for best results.
2 citations
,
October 2021 in “Clinical Epidemiology and Global Health” High uric acid levels are more common in PCOS patients, especially those with androgenic PCOS, and are linked with increased cardiovascular risk and other metabolic issues.
1 citations
,
June 2025 in “International Journal of Molecular Sciences” Hirsutism in GCC countries is influenced by genetics, obesity, and lifestyle, with cultural stigma delaying treatment, highlighting the need for tailored health strategies.
1 citations
,
July 2024 in “Journal of Plastic Reconstructive & Aesthetic Surgery” Estrogen therapy can help stabilize the hairline in transfeminine individuals.
1 citations
,
January 2024 in “Journal of personalized medicine” Hormonal imbalances during menopause may significantly contribute to Frontal Fibrosing Alopecia.
1 citations
,
July 2023 in “Frontiers in Immunology” Oxidative stress and immune dysfunction are linked to both Hashimoto's thyroiditis and polycystic ovary syndrome, with diet and specific treatments important for managing these conditions.
1 citations
,
July 2022 in “JEADV Clinical Practice” New and existing treatments for hair loss show promise, with some being more effective for men and others for women.
November 2025 in “Molecules” Microextraction techniques improve hormone testing while being environmentally friendly.
June 2025 in “Preprints.org” EDA is vital for bone and cartilage formation and could help treat skeletal disorders.
January 2025 in “Case Reports in Genetics” A rare gene variant causes sexual development issues in siblings, needing personalized treatment.