research 5α-Reductase Isoenzymes: From Neurosteroid Biosynthesis to Neuropsychiatric Outcomes
Finasteride and dutasteride may cause depression and anxiety, especially in younger men.
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150-180 / 1000+ results research Comprehensive Safety Exposure‐Response Analysis to Support Ritlecitinib Dose Selection
A 50 mg non-loading dose of ritlecitinib is safe for adults and adolescents.
research Advances in Nanotechnology Research in Food Production, Nutrition, and Health
Nanotechnology can improve food safety, nutrition, and health, but safety and regulation challenges need addressing.
research Advances in Nanocarrier Systems for Dermatologic Transdermal Drug Delivery: A Chemical and Molecular Review
Nanocarriers show promise for improving skin drug delivery in treating skin conditions.
research Aspects of Geriatric-Tourism, Different from Third Age Tourism and Its Relationship with Physiotherapy, Rehabilitation and Thermal Treatments
Geriatric tourists in Turkey mainly seek thermal treatments and medical services in major cities.
research Recommendations from the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome
The 2023 guideline for PCOS suggests using updated diagnostic criteria, assessing related health risks, and recommends lifestyle changes and specific treatments for symptoms and fertility issues.
research Role of Drug Repurposing in Sustainable Drug Discovery
Drug repurposing speeds up drug development, saves money, and has led to about a third of new drug approvals.
research Evaluation of the efficacy and treatment-emergent adverse events of deuruxolitinib for moderate to severe alopecia areata: a dose-ranging meta-analysis of 1,372 randomized patients
Deuruxolitinib effectively improves hair regrowth in alopecia areata but requires monitoring for side effects.
research Diagnostic criteria for enduring sexual dysfunction after treatment with antidepressants, finasteride and isotretinoin
The document sets criteria for diagnosing long-term sexual dysfunctions caused by certain medications.
research EU Legal and Regulatory Update
The document updates on EU legal changes, including pharmaceutical patents, class actions in Italy, and various drug-related rulings.
research Pathways to inflammation: acne pathophysiology
Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
research La FDA aprueba Litfulo® (ritlecitinib) para el tratamiento de la alopecia areata grave en adolescentes y adultos
The FDA approved Litfulo® for treating severe alopecia areata in people aged 12 and older.
research The effect of St. John’s wort on the pharmacokinetics, metabolism and biliary excretion of finasteride and its metabolites in healthy men
St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.
research Rivaroxaban-induced hair loss
Rivaroxaban may cause hair loss.
research Metformin: an old medication of new fashion: evolving new molecular mechanisms and clinical implications in polycystic ovary syndrome
Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.
research High prevalence of chronic thyroiditis in patients with polycystic ovary syndrome
People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.
research Cardiovascular disease risk in women with hyperandrogenism, oligomenorrhea/menstrual irregularity or polycystic ovaries (components of polycystic ovary syndrome): a systematic review and meta-analysis
Women with irregular periods have a higher risk of heart disease.
research Bladder cancer survival in men using 5-alpha-reductase inhibitors
Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.
research A case of red lunulae after haematopoietic stem cell transplantation
Adjusting the medication tacrolimus resolved a boy's red nail beds after a stem cell transplant.
research Discriminating between virilizing ovary tumors and ovary hyperthecosis in postmenopausal women: clinical data, hormonal profiles and image studies
The research found that MRI and certain hormone levels can help tell apart ovarian tumors from hyperthecosis in postmenopausal women, but tissue analysis is still needed for a definite diagnosis.
research The use of cyproterone acetate/ethinyl estradiol in hyperandrogenic skin symptoms – a review
Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.
research Traitement par pompe à insuline : Accu-Chek FlexLink Plus, le premier cathéter à aiguille auto-rétractable et Accu-Chek LinkAssist Plus
The Accu-Chek FlexLink Plus and Accu-Chek LinkAssist Plus make insulin pump use safer, simpler, and more comfortable.
research Venous and pulmonary thromboembolism and combined hormonal contraceptives. Systematic review and meta-analysis
Some birth control pills have a higher risk of blood clots than others.
research African baobab (Adansonia digitata) fruit as promising source of procyanidins
African baobab fruit is a good source of antioxidants and micronutrients, but too much can cause laxative effects.
research Association of Suicidality and Depression With 5α-Reductase Inhibitors
Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.
research Indirect clinical markers for the detection of anabolic steroid abuse beyond the conventional doping control in athletes
New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.
research Cicatricial alopecia: What’s new in etiology?
Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.
research Effectiveness of platelet-rich plasma in long-lasting post-viral olfactory dysfunction: a case-series
Platelet-rich plasma (PRP) significantly improves long-lasting post-viral smell dysfunction.
research Lower Urinary Tract Symptoms: What’s New in Medical Treatment?
New drugs and combination therapies are improving treatment for lower urinary tract symptoms.
research Finasteride treatment and male breast cancer: a register-based cohort study in four Nordic countries
Finasteride use may increase the risk of male breast cancer.