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Blocking a specific enzyme in male rat fetuses leads to the development of nipples and feminized genitalia.

Progesterone may help trans women with breast development and health, but more research is needed.

Blocking androgen receptors early in life increases estrogen levels and reduces sexual motivation in male rats.

Facial feminization surgery helps make facial features more feminine, improving patient satisfaction and safety.

Gender-affirming dermatology treatments generally improve mental well-being for transgender individuals, but more research is needed.

Gender-affirming hormone therapy may increase heart disease risk in transgender individuals.

Females with 5 alpha-reductase-2 deficiency have less body hair, no acne, normal fertility, and delayed menarche.

Women also use 5α-reductase inhibitors for hair loss and hirsutism.

Finasteride causes reproductive changes in male rats.

Gender-affirming hormone therapy and surgery affect gut bacteria differently.

More research is needed to improve lower body gender affirmation techniques.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Early androgen exposure affects hormone receptor expression in adult female rats' brains, but not in males.

Finasteride reduces prostate size and DHT in male mastomys but not in females.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Finasteride reduces alcohol withdrawal severity in male mice but increases it in female mice.

Estrogen alone may effectively suppress testosterone in some transfeminine individuals.

Gender differences affect allergy prevalence, severity, and response to environmental toxins, with women often more affected than men.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Finasteride worsens alcohol withdrawal in female mice but eases it in male mice.

High doses of testosterone disrupt hormone levels and receptor expression in the uterus, affecting fertility.

Testosterone treatment may change estrogen receptor methylation in AFAB individuals.

Mouse genital development depends on male or female hormones for specific features.

Finasteride affects prostate development differently in male and female Mongolian gerbils.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.