September 2021 in “Fertility and Sterility” Older men have different fertility histories and factors affecting fertility, suggesting they may benefit from earlier fertility evaluations.
15 citations
,
March 2015 in “PloS one” Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.
12 citations
,
June 2016 in “Reviews in Endocrine and Metabolic Disorders” Some skin diseases and their treatments can negatively affect male fertility.
June 2026 in “The Journal of Sexual Medicine” Finasteride 1 mg reduces semen quality without affecting hormones.
April 2026 in “The Journal of Urology” Finasteride 1 mg/day reduces semen quality without affecting hormones or sexual function.
June 2023 in “Medicine and Pharmacy Reports” A woman with a specific mutation causing adrenal gland issues faced fertility problems, but careful hormone therapy helped her manage it successfully.
April 2011 in “The FASEB Journal” Amlodipine impairs fertility in male rats by affecting sperm and testicular structure.
88 citations
,
May 2012 in “Human Reproduction Update” Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.
16 citations
,
June 2022 in “Transgender Health” Oocyte retrieval is possible for transgender men on testosterone therapy without affecting fertility outcomes.
5 citations
,
January 2018 in “Research Journal of Pharmacy and Technology” Finasteride significantly reduces fertility in male rats.
2 citations
,
April 2022 in “Annales d Endocrinologie” Recombinant gonadotropins improve future fertility in CHH patients.
1 citations
,
January 2011 in “Journal of Human Reproductive Sciences” Finasteride may decrease semen quality but not harm sperm production, and stopping the drug can improve semen quality; hyperprolactinemia can cause infertility but is treatable with medication.
January 2019 in “Open Access Journal of Nursing” Thai women with PCOS become more aware and change their lifestyle to manage their fertility and symptoms.
77 citations
,
June 2015 in “Nature Reviews Urology” Some common medications can harm male fertility, but many effects can be reversed.
35 citations
,
October 2004 in “Biology of Reproduction” PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
16 citations
,
August 2021 in “Tumor Biology” TMPRSS2 helps viruses enter cells and protects the prostate from inflammation-related cancer.
12 citations
,
February 2025 in “Women s Health” Metformin helps manage PCOS by improving fertility and is safe for pregnancy, especially when combined with certain treatments.
6 citations
,
April 2022 in “Biomedicines” COVID-19 may harm male fertility by affecting sperm production.
2 citations
,
December 2016 in “Clinical and Experimental Obstetrics & Gynecology” Certain health factors can worsen fertility treatment results in women with PCOS.
1 citations
,
July 2023 in “F&S Reviews” Some common medications may harm male fertility by affecting hormones, sperm production, and sexual function.
February 2026 in “Applied Biosciences” The study found potential new DNA patterns in fertility genes, but further testing is needed.
Certain medications can negatively impact male fertility.
January 2005 in “Elsevier eBooks” Insulin resistance and hyperinsulinism are linked to fertility issues and can worsen symptoms of PCOS.
January 2022 in “Skin appendage disorders” Finasteride is effective for male hair loss, but it may cause fertility issues, mental health problems, and rarely, breast growth. Regular health checks can reduce the risk of prostate cancer. Patient understanding and involvement in treatment is important.
97 citations
,
March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
1 citations
,
August 2025 in “Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine” BMI should be considered in future research on dutasteride's effects on fertility.
February 2026 in “European Urology”
December 2025 in “Lviv clinical bulletin” PRP therapy may help with ovarian issues and fertility, but more research is needed.
October 2025 in “Česká gynekologie” Hyperprolactinemia is the most common cause of secondary amenorrhea, followed by drug use.
124 citations
,
July 1997 in “Journal of Biological Chemistry” Overexpressing a specific enzyme in mice causes hair loss and female infertility.