November 2015 in “European Journal of Inflammation” Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.
January 2026 in “Acta Dermatovenerologica Alpina Pannonica et Adriatica” Primary cicatricial alopecia causes permanent hair loss by destroying hair follicles, and its exact cause is unknown.
46 citations
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March 2006 in “Seminars in Cutaneous Medicine and Surgery” Current treatments for cicatricial alopecia can manage symptoms but don't stop hair loss or the disease.
October 1991 in “Archives of Dermatology” The woman has a skin condition involving nodules, scars, and hair loss.
23 citations
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April 2018 in “Journal der Deutschen Dermatologischen Gesellschaft” Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.
June 2025 in “Dermatologic Surgery” Surgery can effectively treat severe eyelid turning out caused by a rare skin disorder.
4 citations
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August 2010 in “Journal of the American Academy of Dermatology” Cicatricial alopecia involves scarring hair loss and can be treated with various medications.
35 citations
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October 2014 in “Wound Repair and Regeneration” The model helps understand scar contraction and develop new treatments.
Pseudopelade is likely an independent disease due to its distinct features.
5 citations
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February 2017 in “Australasian Journal of Dermatology” Scarring hair loss found in female pattern; biopsy needed for diagnosis.
8 citations
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January 2002 in “Piel” Postmenopausal women may experience frontal hairline and eyebrow loss due to cicatricial fibrosis.
6 citations
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April 2021 in “The Journal of Dermatology” Hair regrowth is possible in some cicatricial alopecia patients after treatment, but the reason is unclear.
28 citations
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January 2014 in “Indian Journal of Dermatology, Venereology and Leprology” Chinese patients with primary cicatricial alopecia often have folliculitis decalvans, benefit from treatment, but may experience relapse, with dermoscopy being a useful diagnostic tool.
11 citations
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January 2022 in “Experimental Dermatology” Severe CCCA may be biologically and clinically different from milder forms.
5 citations
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October 2019 in “JAAD Case Reports” These hair loss conditions might be part of a spectrum, not separate issues.
January 2022 in “Przegla̧d dermatologiczny” The document concludes that there are various treatments for diseases linked to scarring hair loss, especially for primary scarring alopecia.
March 2026 in “Journal of the American Academy of Dermatology” The treatment significantly improved lymphocytic cicatricial alopecia symptoms in most patients.
42 citations
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January 2008 in “SKINmed/Skinmed” The article explains how to diagnose and manage certain types of scarring hair loss.
1 citations
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July 2012 in “Springer eBooks” The document concludes that more research is needed to better understand and treat scarring hair loss conditions.
8 citations
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September 2016 in “The American Journal of Dermatopathology” Enlarged sweat gland ducts may indicate scarring hair loss.
July 2022 in “JEADV Clinical Practice” The document concludes that different types of permanent hair loss conditions are related and early treatment is key to preventing further damage.
32 citations
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March 2008 in “SKINmed Dermatology for the Clinician” Accurate diagnosis and tailored treatment are crucial for managing complex hair loss conditions.
July 2020 in “Zenodo (CERN European Organization for Nuclear Research)” Early diagnosis and treatment can lessen the impact of cicatricial alopecia.
July 2018 in “Elsevier eBooks” Early treatment is key to prevent permanent hair loss from scalp conditions that cause scarring.
15 citations
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November 1998 in “Australasian Journal of Dermatology” Cicatricial pemphigoid rarely affects the scalp but is hard to treat when it does.
64 citations
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June 2014 in “Journal of The American Academy of Dermatology” Researchers found a white halo around hair in most patients with a specific type of hair loss, which helps in early diagnosis and treatment.
December 2012 in “Drugs & Therapy Perspectives” Doctors use their experience to choose treatments for scarring hair loss because it's hard to diagnose and treat.
The C-CAT tool helps assess and improve treatment for central centrifugal cicatricial alopecia.
August 1969 in “Archives of Dermatology” After calciphylaxis, rats showed incomplete skin and hair regeneration, resembling scar tissue with fewer hairs.
21 citations
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December 2023 in “Bioengineering & Translational Medicine” Fibroblast and endothelial cell interactions are crucial in forming hypertrophic scars.