research Exosomal microRNA-Based therapies for skin diseases
miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.
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research Nanotechnology-based techniques for hair follicle regeneration
Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.
research Bioengineered skin organoids: from development to applications
Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
research Self-Assembled Peptide Hydrogels in Regenerative Medicine
Peptide hydrogels show promise for healing skin, bone, and nerves but need improvement in stability and compatibility.
research Orchestration of Mesenchymal Stem/Stromal Cells and Inflammation During Wound Healing
Mesenchymal Stem/Stromal Cells (MSCs) help in wound healing and tissue regeneration, but can also contribute to tumor growth. They show promise in treating chronic wounds and certain burns, but their full healing mechanisms and potential challenges need further exploration.
research In vitro strategies for mimicking dynamic cell–ECM reciprocity in 3D culture models
The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
research Hydrobiome of Thermal Waters: Potential Use in Dermocosmetics
Thermal spring waters and their microbes could be good for skin health and treating some skin conditions in skincare products.
research Human Teeth Is Useful Even after Its SHED! So, Why Discard It?
Baby teeth stem cells can potentially grow organs and treat diseases.
research Nanotechnological Interventions and Mechanistic Insights into Wound-Healing Events
Nanotechnology can improve wound healing by enhancing treatments and dressings.
research Stem Cell Therapy for Burns: Story so Far
Stem cell therapy shows promise for better burn healing but needs more research and standardization.
research Referee report. For: Autologous stromal vascular fraction cells combined with platelet-rich plasma for androgenic alopecia treatment: a case series [version 1; peer review: 1 approved with reservations]
The treatment showed promising hair growth results but needs more research.
research Referee report. For: Autologous stromal vascular fraction cells combined with platelet-rich plasma for androgenic alopecia treatment: a case series [version 1; peer review: 2 approved with reservations]
Combining SVF cells with PRP may boost hair growth in androgenic alopecia.
research Meeting Report: 68th Montagna Symposium on the Biology of Skin “Decoding Complex Skin Diseases: Integrating Genetics, Genomics, and Disease Biology”
The symposium highlighted the importance of genetics in understanding and treating complex skin diseases.
research Comprehensive single-cell transcriptomic profiling of the scalp from patients with moderate-to-severe alopecia areata
Alopecia areata involves immune system issues and specific cell types that disrupt hair growth, leading to hair loss.
research Identification of A p300–SP1–BRD4 Transcriptional Axis as a Key Driver of AR Hyperactivation in Polycystic Ovarian Syndrome
Targeting the p300/AR axis may help treat polycystic ovary syndrome.
research Exosome-Based Therapeutics in Dermatology and Beyond: A Narrative Review
Exosome-based treatments may improve skin and hair issues, but more research is needed for safety and effectiveness.
research Engineered Exosomes Co-Delivering EGF and FGF Ameliorate Androgenetic Alopecia in a Mouse Model
Engineered exosomes with EGF and FGF improved hair growth in mice with hair loss.
research Signal Peptide-CUB-EGF-like Domain-Containing Protein 3 (SCUBE3): From Molecule to Therapy
SCUBE3 is a potential target for cancer and alopecia treatment but is challenging to target due to its varied roles.
research Inflammatory Skin Disease in Latin America: Treatment Challenges and Opportunities
Improving education, training, and access to affordable treatments is crucial for better managing inflammatory skin diseases in Latin America.
research Review of Promising Off-Label Use of Deucravacitinib
Deucravacitinib may help treat various immune diseases beyond psoriasis, but more research is needed.
research The Skin Microenvironment: A Dynamic Regulator of Hair Follicle Development, Cycling and Disease
The skin microenvironment significantly affects hair growth and loss, offering potential treatment avenues.
research Erythrodermic Psoriasis in the Context of Emerging Triggers: Insights into Dupilumab-Associated and COVID-19-Induced Psoriatic Disease
Dupilumab and COVID-19 can worsen or trigger psoriasis.
research Referee report. For: Molecular mediators involved in skin healing: a narrative review [version 1; peer review: 1 approved with reservations]
Understanding molecular mediators can improve skin healing treatments.
research Cells, growth factors and biomaterials used in tissue engineering for hair follicles regeneration
Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.
research Advances of Stem Cell Therapeutics in Cutaneous Wound Healing and Regeneration
Stem cells show promise in speeding up wound healing and tissue regeneration.
research Topical drug delivery strategies for enhancing drug effectiveness by skin barriers, drug delivery systems and individualized dosing
Improving topical drug delivery involves overcoming skin barriers and using personalized dosing to enhance effectiveness.
research Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair
Ng2+ perivascular cells in mouse skin come from specific fibroblast types and help in tissue repair.
research Heparin-based sericin hydrogel–encapsulated basic fibroblast growth factor for in vitro and in vivo skin repair
The hydrogel significantly speeds up wound healing and supports skin cell growth.
research The Important Role of Leptin in Modulating the Risk of Dermatological Diseases
Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.
research Activation and regulation of the granulation tissue derived cells with stemness-related properties
Granulation tissue-derived cells can aid wound healing and serve as an alternative source of stem cells for tissue repair.