research Coactivator MED1 Ablation in Keratinocytes Results in Hair-Cycling Defects and Epidermal Alterations
Deleting MED1 in skin cells causes hair loss and skin changes.
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300-330 / 660 resultsresearch Extracellular Vesicles from Activated Dermal Fibroblasts Stimulate Hair Follicle Growth Through Dermal Papilla-Secreted Norrin
Special particles from skin cells can promote hair growth by activating a specific growth signal.
research Novel insights into the pathways regulating the canine hair cycle and their deregulation in alopecia X
The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
research Organoid‐Guided Precision Medicine: From Bench to Bedside
Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
research Back to the Future: From Appendage Development Toward Future Human Hair Follicle Neogenesis
New hair follicles could be created to treat hair loss.
research Developmentally regulated expression of integrin alpha-6 distinguishes neural crest derivatives in the skin
Integrin α6 helps identify different neural crest cell types in the skin.
research Development and Characterization of Dual-Loaded Niosomal Ion-Sensitive In Situ Gel for Ocular Delivery
The gel effectively delivers drugs to the eye, fights bacteria, and protects against oxidative stress.
research Physiology of Testicular Function
The testes produce sperm and hormones essential for male development.
research A Kaleidoscope of Keratin Gene Expression and the Mosaic of Its Regulatory Mechanisms
Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.
research The expanding impact of T-regs in the skin
T-regulatory cells are important for skin health and can affect hair growth and reduce skin inflammation.
research Scar Inhibition in Wound Healing: Mechanisms, Design, and Recent Advances
Advancements in gene therapy, stem cells, and biomaterials show promise for reducing scarring in wound healing, but face clinical challenges.
research Exosome-based Therapies for Androgenetic Alopecia: Mechanisms, MicroRNAs, and Clinical Prospects
Exosome therapy could be a promising new way to treat hair loss.
research TAZ enhances the activity of the AKT signaling pathway to promote adipogenesis of gADSCs
TAZ boosts fat cell formation in goat stem cells by activating a specific signaling pathway.
research Functional regeneration strategies of hair follicles: advances and challenges
Hair follicle regeneration is advancing but still faces challenges in stability and clinical use.
research Disturbance of Immune Microenvironment in Androgenetic Alopecia through Spatial Transcriptomics
Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.
research Microarray Gene Expression Analysis of Lesional Skin in Canine Pemphigus Foliaceus
Canine pemphigus foliaceus involves significant immune activity and shares similarities with human pemphigus.
research Modeling of solar UV-induced photodamage on the hair follicles in human skin organoids
Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.
research Lymphatic Vasculature and Hair Follicle Regeneration
Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
research A Scarless Healing Tale: Comparing Homeostasis and Wound Healing of Oral Mucosa With Skin and Oesophagus
Oral mucosa heals with minimal scarring, offering insights for scarless wound healing.
research miR-29a-5p Inhibits Prenatal Hair Placode Formation Through Targeting EDAR by ceRNA Regulatory Network
miR-29a-5p prevents the formation of early hair structures by targeting a gene important for hair growth and is regulated by a complex network involving lncRNA627.1.
research Mesenchymal–epithelial interactions during hair follicle morphogenesis and cycling
The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
research The Tissue-dependent Keratin 19 Gene Transcription Is Regulated by GKLF/KLF4 and Sp1
GKLF/KLF4 and Sp1 control Keratin 19 gene activity, influencing cancer-related changes.
research Beauty is skin deep: the fascinating biology of the epidermis and its appendages.
The biology of skin and hair is complex and not fully understood.
research Notch Signaling Regulates Late-Stage Epidermal Differentiation and Maintains Postnatal Hair Cycle Homeostasis
Notch signaling is essential for healthy skin and hair follicle maintenance.
research Transcriptional Characteristics Showed That miR-144-y/FOXO3 Participates in Embryonic Skin and Feather Follicle Development in Zhedong White Goose
miR-144-y and FOXO3 play key roles in skin and feather development in Zhedong White geese.
research Innate type 2 immunity controls hair follicle commensalism by Demodex mites
Type 2 immunity helps control mite growth in hair follicles, preventing damage.
research Sonic Hedgehog signalling in the regulation of barrier tissue homeostasis and inflammation
Sonic Hedgehog helps keep skin and airway barriers healthy and reduces inflammation.
research EGFR Controls Hair Shaft Differentiation in a p53-Independent Manner
EGFR helps control how hair grows and forms without needing p53 protein.
research Maintenance of Barrier Tissue Integrity by Unconventional Lymphocytes
Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.
research Planar Proton Minibeam Irradiation Elicits Spatially Confined DNA Damage in a Human Epidermis Model
Proton minibeam radiotherapy may reduce skin side effects by causing localized DNA damage.