research G4, is a new transgenic mouse model for the polycystic ovaries syndrome
Researchers created a new mouse model, G4, that mimics human PCOS symptoms and links the condition to a specific gene.
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960-990 / 1000+ resultsresearch Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart
Mice with human-like EGFR had growth issues, skin defects, heart problems, and unusual bone development.
research Experimental Models and Molecular Pathogenesis: An Integrated Review of Alopecia
Current models for studying alopecia are inadequate, and more human-like systems are needed.
research Imaging tumor angiogenesis with fluorescent proteins
Fluorescent proteins in mouse models effectively visualize tumor blood vessel growth.
research Gene Editing Technologies in Aesthetic Dermatology—Mechanisms, Emerging Applications, and Patient Safety Paradigms
Gene editing holds promise for skin treatments but needs careful safety and ethical consideration.
research 3D Bioprinting for Engineered Tissue Constructs and Patient‐Specific Models: Current Progress and Prospects in Clinical Applications
Bioprinting is advancing towards creating personalized tissues and organs, but challenges remain for clinical use.
research Three-Dimensional-Bioprinted Non-Small Cell Lung Cancer Models in a Mouse Phantom for Radiotherapy Research
3D bioprinted lung cancer models in a mouse-like structure offer a better way to study radiation effects without using live animals.
research Traditional Strategies and Cutting-Edge Technologies Used for Animal Breeding: A Comprehensive Review
Gene editing is the future of efficient and precise animal breeding.
research Enhanced Differentiation Potential of Pigmented Human Epidermal Equivalents
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
research 501 Next-generation in vitro testing: microfluidic models for aging, wound healing, and oral tissue analysis in safety, efficacy, and permeation studies
Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.
research Editorial overview: Embroidering the canvas of life
The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.
research 591 A New 3D Skin Model Containing Autologous Immune Cells Reconstructed by Tissue Engineering
Researchers developed a 3D skin model with its own immune and blood vessel cells to better understand skin health and disease.
research Organoid‐Guided Precision Medicine: From Bench to Bedside
Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
research Characterization of a new, inducible transgenic mouse model with GFP expression in melanocytes and their precursors
A new mouse model helps study melanocyte cells using GFP expression.
research Reconstitution of human skin in vitro using readily available sources: Novel studies of tumour promotion
A lab model of human skin was created to study skin tumor promoters without using actual human skin.
research Biological, cellular, and molecular characteristics of an inducible transgenic skin tumor model: a review
research Animal models of psoriasis—highlights and drawbacks
Animal models help study psoriasis but have limitations and don't fully mimic the human disease.
research A Novel Model System to Identify Cellular and Molecular Defects Underlying Rare Genetic Disorders
The new model helps understand and develop treatments for genetic skin disorders like AEC.
research In vitro interactions between sensory nerves, epidermis, hair follicles and capillaries in a tissue‐engineered reconstructed skin
The model effectively studies how sensory nerves interact with skin components, aiding research on wound healing and hair growth.
research Bioengineering a humanized acne microenvironment model: Proteomics analysis of host responses to Propionibacterium acnes infection in vivo
A new model helps study acne and test treatments.
research 565 hiPSC-derived skin organoids as tools for disease modelling: characterization of the epidermal-dermal junction
Human-induced stem cell-created skin models can help understand skin diseases by studying the skin's layers.
research CRISPR/Cas9-mediated Generation ofCOL7A1-deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa
Scientists created cell lines to study a genetic skin disorder using CRISPR technology.
research Advancing skin model development: A focus on a self-assembled, induced pluripotent stem cell-derived, xeno-free approach
A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
research Generation of iPS-derived model cells for the analysis of hair development
Researchers created a cell model to study hair growth and test hair-growth drugs.
research Engineering a New Mouse Model for Vitiligo
A new mouse model for vitiligo helps study immune responses and potential treatments.
research Generation of iPS-derived model cells for analyses of hair shaft differentiation
Researchers created a mouse cell line to study hair growth and test hair growth drugs.
research Animal models and culture methods in the study of hair growth
The new microneedle method delivers hair loss treatment more effectively by enhancing growth pathways.
research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
research Development and validation of a comprehensive in vitro organ model for androgenetic alopecia
The new model mimics hair loss and helps test treatments.