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research Immunopotentiator from Pantoea agglomerans 1 (IP-PA1) Promotes Murine Hair Growth and Human Dermal Papilla Cell Gene Expression.

July 2016 in “PubMed”

IP-PA1 helps grow hair in mice and affects human cell growth-related genes differently than traditional hair growth treatments.

research Spatiotemporal Expression, Distribution, and Processing of POMC and POMC-derived Peptides in Murine Skin

49 citations , July 2000 in “Journal of Histochemistry & Cytochemistry”

POMC-derived peptides are important for skin functions like immune response and stress management.

research Peptidylarginine Deiminase Isoforms Are Differentially Expressed in the Anagen Hair Follicles and Other Human Skin Appendages

71 citations , June 2005 in “Journal of Investigative Dermatology”

PAD enzymes play a key role in hair growth and structure.

research PHOSPHATIDES IN MOUSE EPIDERMIS UNDERGOING NORMAL AND ABNORMAL GROWTH CHANGES.

13 citations , April 1964 in “PubMed”

Phosphatide distribution in mouse skin remains consistent in both normal and cancerous growths.

Proteomic Analysis Identifies Differentially Expressed Proteins Participating in Forming Type III Brush Hair in Yangtze River Delta White Goat

research Proteomic analysis identifies differentially expressed proteins participating in forming Type III brush hair in Yangtze River Delta white goat

8 citations , January 2015 in “Genetics and molecular research”

Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.

research Immunofluorescence analysis of the basement membrane zone components in human anagen hair follicles

29 citations , July 2003 in “Experimental Dermatology”

The upper hair follicle is stable, while the lower part allows movement during hair growth.

research Ptch2 is a Potential Regulator of Mesenchymal Stem Cells

3 citations , April 2022 in “Frontiers in Physiology”

Ptch2 plays a key role in controlling stem cell function and the ability to regenerate after birth.

research Novel complex of cosmetic ingredients with promising action in preventing hair loss and follicular aging through mechanism involving enrichment of WNT/signaling, mitochondrial activity, and stem cells maintenance

8 citations , November 2020 in “Journal of Cosmetic Dermatology”

The ingredients may help prevent hair loss and aging by boosting hair growth signals and reducing stress and hormone effects.

research A proteoglycan-based topical treatment for hair greying: in vitro antioxidant and pro-melanogenic effects

January 2026 in “Frontiers in Medicine”

PP-PTKL may help treat hair greying, but more testing is needed.

research PINK1 deficiency rewires early immune responses in a mouse model of Parkinson’s disease triggered by intestinal infection

4 citations , May 2025 in “npj Parkinson s Disease”

PINK1 is important for controlling gut immune responses linked to early Parkinson's disease.

research Conditional Knockout in Mice Reveals the Critical Roles of Ppp2ca in Epidermis Development

14 citations , May 2016 in “International Journal of Molecular Sciences”

PP2Acα is essential for proper hair and skin development.

research LncRNA018392 promotes the proliferation of Liaoning cashmere goat skin fibroblasts by upregulating CSF1R through binding to SPI1

3 citations , August 2024 in “Molecular Biology Reports”

LncRNA018392 helps goat skin cells grow by increasing CSF1R.

A Novel Cell-Penetrating Peptide Supports Hair Follicle Growth Through Anti-Inflammatory and Growth Factor-Associated Mechanisms in Preclinical Models

research A novel cell-penetrating peptide supports hair follicle growth through anti-inflammatory and growth factor–associated mechanisms in preclinical models

April 2026 in “BMC Biotechnology”

A new peptide, DualPep-ALO, may help hair growth by reducing inflammation and boosting growth factors.

research Induction of hair growth by skin irritants and its relation to skin protein kinase C isoforms

10 citations , April 1999 in “British journal of dermatology/British journal of dermatology, Supplement”

Skin irritants can promote hair growth by affecting specific skin proteins.

research Faculty Opinions recommendation of Modulation of phospholipid signaling by GLABRA2 in root-hair pattern formation.

September 2003 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

GLABRA2 gene controls root-hair growth by regulating phospholipid signaling.

Site of Beige and Leaden Pigment Gene Expression Determined by Recombinant Embryonic Skin Grafts and Aggregation Mouse Chimaeras Employing Sash Homozygotes

research Site of beige (bg) and leaden (ln) pigment gene expression determined by recombinant embryonic skin grafts and aggregation mouse chimaeras employing sash (W^sh) homozygotes

7 citations , October 1985 in “Genetics Research”

Beige and leaden pigment genes act within melanocytes, affecting pigment patterns.

research Functions of peroxisome proliferator‐activated receptors (PPAR) in skin homeostasis

46 citations , November 2004 in “Lipids”

PPARs help regulate skin health and could be used to treat skin disorders.

research Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular repair responses and angiogenesis

5 citations , June 2024 in “Pharmacological Research”

FOL-026 peptide may help hair growth and cardiovascular health by improving blood flow and cell functions.

research Expression of Peroxisome Proliferator Activated Receptors (PPARs) in Human Hair Follicles and PPARα Involvement in Hair Growth

51 citations , September 2000 in “Acta dermato-venereologica”

PPAR alpha may help in hair growth and could be a target for treatment.

research Mutations in γ-secretase subunit–encoding PSENEN underlie Dowling-Degos disease associated with acne inversa

87 citations , March 2017 in “Journal of Clinical Investigation”

PSENEN gene mutations can cause both Dowling-Degos disease and acne inversa.

research Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors

136 citations , April 2013 in “Clinical Cancer Research”

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

research KIF18B is a cell-type specific regulator of spindle orientation in the epidermis

June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.

research Proteome Analysis of Human Hair Shaft

122 citations , January 2006 in “Molecular & Cellular Proteomics”

Human hair contains many proteins, with some being highly abundant and modified.

research Structural Stability of Wild Type and Mutated α-Keratin Fragments: Molecular Dynamics and Free Energy Calculations

40 citations , September 2004 in “Biomacromolecules”

The Glu413Lys mutation in keratin affects hair stability, while Glu413Asp does not.

Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia

research Prostaglandin D ₂ Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia

205 citations , March 2012 in “Science Translational Medicine”

PGD2 stops hair growth and is higher in bald men with AGA.

research 453 Signaling by Senescent Melanocytes Induces New Hair Growth and Informs Hair Growth-Activating Injectable for Androgenetic Alopecia

November 2025 in “Journal of Investigative Dermatology”

AMP-303 injections can increase hair growth in androgenetic alopecia with minimal side effects.

research SlPHL1, a MYB‐CC transcription factor identified from tomato, positively regulates the phosphate starvation response

11 citations , July 2021 in “Physiologia Plantarum”

SIPHL1 from tomato enhances plants' response to low phosphate levels.

research Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes

226 citations , August 2006 in “Molecular and Cellular Biology”

EGF signaling affects gene expression in skin cells, influencing hair growth and potentially cancer.

research Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis

47 citations , September 2012 in “Human molecular genetics online/Human molecular genetics”

Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.

research Diagnostic Significance of MIG (Monokine Induced by Gamma Interferon) and IP-10 (Interferon gamma-induced protein 10) Chemokines in Alopecia Areata

June 2025 in “Medical Science Journal for Advance Research”

Higher levels of MIG and IP-10 may help diagnose and monitor Alopecia Areata.

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