11 citations
,
June 2022 in “Frontiers in immunology” New protein changes may be involved in the immune attack on hair follicles in alopecia areata.
11 citations
,
October 2021 in “Stem Cell Research & Therapy” Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.
3 citations
,
May 2023 in “Precision clinical medicine” Researchers found four genes that could help diagnose severe alopecia areata early.
1 citations
,
January 2025 in “Genes & Diseases” Understanding T cells and signaling pathways can lead to better treatments for hair loss.
February 2026 in “International Journal of Web of Multidisciplinary Studies” Restoring microbial balance and using exosome therapies may help treat hair disorders like alopecia and acne.
August 2024 in “Journal of the Egyptian Womenʼs Dermatologic Society” SOX10 in hair follicles is linked to inflammation in alopecia areata.
Different stem cells are key for hair growth and health, and understanding their regulation could help treat hair loss.
73 citations
,
April 2019 in “Experimental Dermatology” The scalp's microorganisms significantly affect hair health and disease.
17 citations
,
July 2019 in “Lupus Science & Medicine” Plucked hair follicles can help diagnose scalp lupus.
14 citations
,
June 2017 in “Immunity” Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.
245 citations
,
October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
131 citations
,
November 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.
31 citations
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May 2008 in “Drug Discovery Today: Disease Mechanisms” Different hair growth problems are caused by genetic issues or changes in hair growth cycles, and new treatments are being developed.
28 citations
,
February 2016 in “F1000Research” Understanding glycans and enzymes that alter them is key to controlling hair growth.
10 citations
,
May 2020 in “Dermatology Research and Practice” Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.
3 citations
,
May 2023 in “International Journal of Molecular Sciences” A new treatment using nanoparticles can effectively prevent and reduce hair loss caused by chemotherapy.
November 2025 in “Advanced Science” The treatment using a special hydrogel shows promise for promoting hair growth.
March 2023 in “Медицинский совет” COVID-19 may cause different types of hair loss, and the virus's effects on hair could help understand its impact on other body parts.
February 2026 in “BMC Genomics” MEG3-miRNAs help control wool traits in young Tan sheep by regulating immune responses, but their decline with age leads to wool changes.
92 citations
,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
56 citations
,
March 2015 in “Journal of Investigative Dermatology” Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.
18 citations
,
March 2023 in “Molecular Therapy — Nucleic Acids” Mechanical stimuli and CCL2 can help regenerate hair follicles in adult mice.
2 citations
,
May 2024 in “Immunity” Stem cells help control the immune response to improve wound healing.
1 citations
,
November 2025 in “Stem Cell Research & Therapy” Immortalized hair follicle cells could be useful for regenerative medicine and treating inflammation and oxidative stress.
2 citations
,
June 2024 in “Medical Journal of Babylon” Higher CD8+ T cell levels are linked to Alopecia areata in Iraqi patients.
91 citations
,
January 2010 in “Journal of Allergy and Clinical Immunology” NK cells play a role in skin diseases like eczema and psoriasis.
45 citations
,
April 2019 in “International Immunology” The study concluded that immune cells attacking hair follicles cause hair loss in alopecia, with genetics and environment also playing a role, and highlighted the potential of certain treatments.
16 citations
,
December 2015 in “Journal of Investigative Dermatology” Alopecia areata involves persistent gene abnormalities and immune activity, even in regrown hair, suggesting a risk of relapse.
January 2025 in “SKIN The Journal of Cutaneous Medicine” Calcipotriol's effectiveness for treating alopecia areata is unclear and needs more research.
August 2024 in “International Journal of Molecular Sciences” Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.