research Biallelic HEPHL1 variants impair ferroxidase activity and cause an abnormal hair phenotype
Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.
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research DMBA/TPA Treatment Is Necessary for BCC Formation from Patched Deficient Epidermal Cells in Ptch flox/flox CD4Cre +/− Mice
Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.
research Epidermal stem cells: an update on their potential in regenerative medicine
Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
research The importance and use of stem cells in dermatology
Stem cells show promise for treating skin conditions and aiding healing.
research Stem Cells in Tissue Engineering
Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
research Isolating subpopulations of human epidermal basal cells based on polyclonal serum against trypsin-resistant CSPG4 epitopes
The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
research Metabolic Regulation of Stem Cells in Aging
Eating less can improve stem cell function and increase lifespan.
research Modulating the stem cell niche for tissue regeneration
Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
research 14. Wound Healing; Cutaneous Therapy; Hair
Certain hairstyles can cause scalp diseases, smoking is linked to hair loss, 5% minoxidil foam is effective for hair loss treatment, and various factors influence wound healing and hair growth.
research Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth
The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.
research Calcium regulation of stem cells
Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
research Stem Cells and the Niche: A Dynamic Duo
Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.
research Epigenetic control of adult stem cell function
Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
research Paneth Cells in Intestinal Homeostasis and Tissue Injury
Paneth cells help support stem cells and aid tissue regeneration after injury.
research TGF-β family signaling in stem cells
TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
research Anti-aging Properties of Conditioned Media of Epidermal Progenitor Cells Derived from Mesenchymal Stem Cells
EPC-CM can reduce skin aging signs by boosting the skin's defense system.
research Discovering New Progenitor Cell Populations through Lineage Tracing and In Vivo Imaging
New methods have helped find cells that create other cells in the body.
research Wnt Signaling Regulates Symmetry of Division of Neural Stem Cells in the Adult Brain and in Response to Injury
Wnt signaling helps control how brain stem cells divide and is important for brain repair after injury.
research Mouse Spermatogenesis Reflects the Unity and Diversity of Tissue Stem Cell Niche Systems
Mouse spermatogenesis shows that stem cells can behave flexibly and move widely in open environments.
research Comparative characteristics of human stem cells
Human stem cells have diverse sources and potential uses in medicine.
research Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization
Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
research Epidermal Notch1 recruits innate lymphoid cells to orchestrate normal skin repair
Notch1 helps skin heal by attracting cells that aid repair.
research Concise Review: The Plasticity of Stem Cell Niches: A General Property Behind Tissue Homeostasis and Repair
Stem cell niches are adaptable and key for tissue maintenance and repair.
research Capturing Stem Cell Behavior Using Intravital and Live Cell Microscopy
Stem cells are more dynamic and adaptable than previously believed.
research From basic biology to engineered therapies: the keratinocyte stem cell playbook
Keratinocyte stem cells are crucial for skin renewal and have potential in wound healing and tissue regeneration.
research Skin Deep and Deeper: Multiple Pathways in Basal Cell Carcinogenesis
The research suggests new treatments for skin cancer could target specific cell growth pathways.
research Pentacyclic Triterpenoid Maslinic Acid Promotes Hair Growth Comparable to Minoxidil: A New Insight on the Potential Involvement of Cilia Activity
Maslinic acid from olive extracts promotes hair growth like minoxidil.
research Keeping up with the neighbours: local synchronisation of cell fate decisions during development
Cells communicate with neighbors to coordinate their development.
research Androgenetic Alopecia
Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.
research Regeneration, Wound Healing and Cancer
The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.