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GlossaryDermal Papilla Cell Proliferation

cells in hair follicle base multiply, promoting hair growth

Dermal Papilla Cell Proliferation refers to the process by which cells in the dermal papilla, a specialized structure at the base of hair follicles, multiply and grow. This cell activity is crucial for hair growth and regeneration, as these cells send signals that regulate the hair cycle and influence the formation of new hair shafts.

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research Improvement of cell proliferation and antioxidant activity of silymarin in hair follicles dermal papillae isolated from the human scalp: Comparison with vitamin C effects

8 citations , January 2020 in “International Journal of Trichology”

Silymarin improves hair follicle health better than vitamin C by boosting cell growth and reducing oxidative stress.

research Impact of Dongeui Hot Spring Water Complex with Sea Slug Extract on Antioxidant Activity and Hair Papilla Cell Proliferation

December 2024 in “Journal of Health and Beauty”

Dongeui Hot Spring Water Complex with sea slug extract may help prevent hair loss and improve scalp health.

research Impact of Dongeui Hot Spring Water Complex with Sea Slug Extract on Antioxidant Activity and Hair Papilla Cell Proliferation

December 2024 in “Journal of Health and Beauty”

Dongeui Hot Spring Water Complex with sea slug extract may help prevent hair loss by boosting antioxidants and promoting hair cell growth.

research Effect of Orthosiphon stamineus plant extract on in vitro dermal papilla cell proliferation and ex vivo hair growth

1 citations , January 2017 in “Deleted Journal”

Orthosiphon stamineus extract can significantly boost hair growth and cell proliferation in hair loss patients.

Methanol Extract of Peach Kernel Induces Human Hair Follicle Dermal Papilla Cell Proliferation via the Extracellular Signal-Regulated Kinase Signaling Pathway

research Methanol Extract of Peach Kernel Induces Human Hair Follicle Dermal Papilla Cell Proliferation via the Extracellular Signal-Regulated Kinase Signaling Pathway

January 2024 in “Indian Journal of Pharmaceutical Sciences”

Peach kernel extract may promote hair growth by boosting cell growth in hair follicles.

research Injectable platelet rich fibrin facilitates hair follicle regeneration by promoting human dermal papilla cell proliferation, migration, and trichogenic inductivity

2 citations , October 2021 in “Experimental Cell Research”

Injectable platelet-rich fibrin helps hair growth by boosting key cell functions.

research Effect ofCinnamomum osmophloeumKanehira Leaf Aqueous Extract on Dermal Papilla Cell Proliferation and Hair Growth

20 citations , February 2018 in “Cell transplantation”

Cinnamomum osmophloeum leaf extract may help treat hair loss by promoting hair growth and increasing hair cell proliferation.

Pantothenic Acid Promotes Dermal Papilla Cell Proliferation in Hair Follicles of American Minks via Inhibitor of DNA Binding 3/Notch Signaling Pathway

research Pantothenic acid promotes dermal papilla cell proliferation in hair follicles of American minks via inhibitor of DNA Binding 3/Notch signaling pathway

11 citations , April 2020 in “Life sciences”

Pantothenic acid helps mink hair follicles grow by affecting certain cell signals.

research Herbal Extracts Induce Dermal Papilla Cell Proliferation of Human Hair Follicles

24 citations , January 2015 in “Annals of Dermatology”

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

research Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation

71 citations , January 2019 in “International journal of biological sciences”

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

research FGF22 Secreted by Hair Papilla Cells Regulates Hair Follicle Stem Cell Proliferation and Differentiation

November 2025 in “Biomolecules”

FGF22 helps hair follicle stem cells grow and develop.

research Heat-Killed Enterococcus faecalis EF-2001 Induces Human Dermal Papilla Cell Proliferation and Hair Regrowth in C57BL/6 Mice

4 citations , May 2022 in “International journal of molecular sciences”

Heat-killed Enterococcus faecalis EF-2001 may promote hair growth and transition hair follicles to the growth phase.

Lactoferrin Promotes Hair Growth in Mice and Increases Dermal Papilla Cell Proliferation Through Erk/Akt and Wnt Signaling Pathways

research Lactoferrin promotes hair growth in mice and increases dermal papilla cell proliferation through Erk/Akt and Wnt signaling pathways

18 citations , April 2019 in “Archives of Dermatological Research”

Lactoferrin helps mice grow hair by increasing cell growth and hair follicle development.

Hair Growth-Promoting Mechanisms of Red Ginseng Extract Through Stimulating Dermal Papilla Cell Proliferation and Enhancing Skin Health

research Hair Growth-Promoting Mechanisms of Red Ginseng Extract through Stimulating Dermal Papilla Cell Proliferation and Enhancing Skin Health

3 citations , September 2021 in “Journal of Food Science and Nutrition”

Red Ginseng Extract helps hair grow and improves skin health by stimulating cell growth and enhancing the body's antioxidant defense system.

research Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway

2 citations , January 2022 in “Oxidative Medicine and Cellular Longevity”

Exosomes from dermal papilla cells help hair follicle stem cells grow and survive.

Bacillus/Trapa Japonica Fruit Extract Ferment Filtrate Enhances Human Hair Follicle Dermal Papilla Cell Proliferation via the Akt/ERK/GSK-3β Signaling Pathway

research Bacillus/Trapa japonica Fruit Extract Ferment Filtrate enhances human hair follicle dermal papilla cell proliferation via the Akt/ERK/GSK-3β signaling pathway

10 citations , May 2019 in “BMC Complementary and Alternative Medicine”

The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.

research Comprehensive Transcriptome Analysis of Hair Follicle Morphogenesis Reveals That lncRNA-H19 Promotes Dermal Papilla Cell Proliferation through the Chi-miR-214-3p/β-Catenin Axis in Cashmere Goats

7 citations , September 2022 in “International journal of molecular sciences”

The research found that the molecule lncRNA-H19 helps hair follicle cells grow by affecting certain cell pathways in cashmere goats.

research FCP 3 : Platelet rich plasma induced hair growth in alopecia patients partially through dermal papilla cell proliferation, BCl-2 and KGF up-regulation

January 2014 in “프로그램북(구 초록집)”

Platelet-rich plasma treatments help hair growth in people with hair loss by increasing certain cell growth and protein levels.

CARI ONE Induces Anagen Phase of Telogenic Hair Follicles Through Regulation of β-Catenin, Stimulation of Dermal Papilla Cell Proliferation, and Melanogenesis

research CARI ONE Induces Anagen Phase of Telogenic Hair Follicles Through Regulation of β-Catenin, Stimulation of Dermal Papilla Cell Proliferation, and Melanogenesis

3 citations , April 2014 in “Journal of Dietary Supplements”

CARI ONE helps start hair growth and makes hair follicles bigger and more numerous.

research effects Of Low-level Laser Therapy (lllt) On Dermal Papilla Cell Proliferation And Insulin-like Growth Factor-1 (igf-1) Secretion From Balding Hair Follicles : #lb12

April 2014

research Vitamin A regulates dermal papilla cell proliferation and apoptosis under heat stress via IGF1 and Wnt10b signaling

2 citations , August 2023 in “Ecotoxicology and environmental safety”

Vitamin A helps rabbit skin cells grow and survive heat stress.

research Teicoplanin alleviates androgenetic alopecia through inhibition of androgen receptor expression and enhancing dermal papilla cell proliferation

February 2026 in “European Journal of Pharmacology”

Teicoplanin may help treat hair loss by reducing androgen receptors and boosting hair cell growth.

research An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation.

154 citations , October 1996 in “Proceedings of the National Academy of Sciences of the United States of America”

Estrogen affects hair growth and skin cell multiplication.

research Outer root sheath cells secrete oxytocin for hair growth promotion and stem cell proliferation

March 2026 in “Journal of Bioscience and Bioengineering”

Oxytocin from hair cells helps hair growth and stem cell increase.

research An estrogen receptor pathwayregulates thetelogen-anagen hair follicle transition andinfluences epidermal cell proliferation (epidermis/estrogen/keratinocyte/differentiation/mesenchymal

January 1996

The estrogen receptor pathway controls hair growth cycles and affects skin cell growth.

Induction of Hair Growth in Hair Follicle Cells and Organ Cultures Upon Treatment with 30 kHz Frequency Inaudible Sound via Cell Proliferation and Antiapoptotic Effects

research Induction of hair growth in hair follicle cells and organ cultures upon treatment with 30 kHz frequency inaudible sound via cell proliferation and antiapoptotic effects

January 2022 in “Biomedical Reports”

Inaudible sound at 30 kHz can boost hair growth and decrease hair loss by promoting cell growth and reducing cell death in hair follicles.

research Regulatory Effects of FGF9 on Dermal Papilla Cell Proliferation in Small-Tailed Han Sheep

May 2023 in “Genes”

FGF9 helps hair follicles grow in small-tailed Han sheep by affecting cell growth and certain signaling pathways.

MiR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells

research miR-140-5p in Small Extracellular Vesicles From Human Papilla Cells Stimulates Hair Growth by Promoting Proliferation of Outer Root Sheath and Hair Matrix Cells

18 citations , December 2020 in “Frontiers in cell and developmental biology”

miR-140-5p in certain cell vesicles helps hair growth by boosting cell proliferation.

research Effect of minoxidil on proliferation and apoptosis in dermal papilla cells of human hair follicle

149 citations , March 2004 in “Journal of Dermatological Science”

Minoxidil boosts hair growth by increasing cell production and survival.

research Differences in Hair Follicle Dermal Papilla Volume are Due to Extracellular Matrix Volume and Cell Number: Implications for the Control of Hair Follicle Size and Androgen Responses

231 citations , December 1999 in “Journal of Investigative Dermatology”

Hair follicle size is mainly influenced by the number of cells and extracellular matrix volume, with cell number having a larger impact.