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GlossaryHeparin

medication that prevents blood clots by inhibiting clotting proteins

Heparin is a medication and naturally occurring substance in the body that prevents blood clots by inhibiting certain proteins involved in the clotting process. It is commonly used in medical settings to treat and prevent conditions like deep vein thrombosis, pulmonary embolism, and during surgeries to maintain blood flow.

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research Eczema-like, erythematous, infiltrated plaques: A common side effect of subcutaneous heparin therapy

63 citations , October 1989 in “Journal of The American Academy of Dermatology”

Red, swollen skin patches are a common allergic reaction to heparin injections, and testing with different heparin types can help find a suitable treatment.

research Applications and Implications of Heparin and Protamine in Tissue Engineering and Regenerative Medicine

15 citations , January 2014 in “BioMed Research International”

Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.

Generalized Cutaneous Necrosis: A Complication of Low-Molecular-Weight Heparin

research Generalised cutaneous necrosis: a complication of low-molecular-weight heparin

11 citations , September 2005 in “International Wound Journal”

A woman developed severe skin damage after using a blood thinner called low-molecular-weight heparin.

research Endogenous Production of Heparin-Binding EGF-Like Growth Factor During Murine Partial-Thickness Burn Wound Healing

70 citations , March 2002 in “Journal of Burn Care & Rehabilitation”

HB-EGF and TGF-α help heal burns by boosting skin cell growth.

research Hair growth inhibition by heparin in mice: a model system for studying the modulation of epithelial cell growth by glycosaminoglycans?

46 citations , May 1991 in “British Journal of Dermatology”

Heparin can inhibit hair growth in mice when injected.

research Heparin-based sericin hydrogel–encapsulated basic fibroblast growth factor for in vitro and in vivo skin repair

22 citations , February 2023 in “Heliyon”

The hydrogel significantly speeds up wound healing and supports skin cell growth.

research Pemphigus Vulgaris Lacking Mucosal Involvement in a German Shepherd Dog: Possible Response to Heparin Therapy

15 citations , June 1992 in “Veterinary Dermatology”

Heparin treatment may help manage pemphigus vulgaris in dogs.

research Collagen-Heparin-FGF2-VEGF Scaffolds Induce a Regenerative Gene Expression Profile in a Fetal Sheep Wound Model

9 citations , August 2024 in “Tissue Engineering and Regenerative Medicine”

Collagen-heparin-FGF2-VEGF scaffolds can improve skin healing.

research Thrombocytosis Associated with Low-Molecular-Weight Heparin

13 citations , July 1996 in “Annals of Internal Medicine”

International medical graduates outperformed U.S. graduates on an internal medicine exam.

research Hypersensitivity reactions to anticoagulant drugs: diagnosis and management options

130 citations , October 2006 in “Allergy”

Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.

research Traditional Anticoagulants and Hair Loss: A Role for Direct Oral Anticoagulants? A Review of the Literature

31 citations , January 2016 in “Drugs - Real World Outcomes”

Some new oral anticoagulants may also cause hair loss and might not be better than traditional ones for preventing hair loss.

research Hypersensitivity Reactions to Anticoagulant Drugs

28 citations , September 2008 in “Current Pharmaceutical Design”

Allergic reactions to blood thinners are rare but can be serious, requiring careful management and alternative treatments.

research Adverse Dermatologic Effects of Cardiovascular Drug Therapy: Part III

15 citations , November 2002 in “Cardiology in Review”

Cardiovascular drugs can cause various skin problems, so recognizing these reactions is important.

research Agent specific effects of anticoagulant induced alopecia

7 citations , May 2017 in “Research and Practice in Thrombosis and Haemostasis”

Some blood thinners can cause hair loss, but switching medications can stop it.

research Tick Bite Alopecia: A Report of Five Cases and Review of the Literature

2 citations , January 2024 in “Skin Appendage Disorders”

Tick bites may cause hair loss due to inflammation from tick saliva.

research Alopecias

January 2015 in “Springer eBooks”

Chronic kidney disease can cause hair loss, which may be related to zinc deficiency or certain medications, and sometimes hair grows back when the underlying issue is treated.

research Drugs affecting blood coagulation, fibrinolysis, and hemostasis

January 2009 in “Side effects of drugs annual”

Some blood-thinning medications can increase the risk of bleeding, and certain factors like genetics and other health conditions affect their safety and effectiveness.

Surface Modification and Endothelialization of Biomaterials as Potential Scaffolds for Vascular Tissue Engineering Applications

research Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications

421 citations , January 2015 in “Chemical Society Reviews”

Improving artificial vascular grafts requires better materials and surface designs to reduce blood clotting and support blood vessel cell growth.

research Hyaluronate Fragments Reverse Skin Atrophy by a CD44-Dependent Mechanism

135 citations , December 2006 in “PLoS Medicine”

Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.

research Management of primary cicatricial alopecias: options for treatment

98 citations , May 2008 in “British Journal of Dermatology”

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

research Autotaxin–lysophosphatidic acid– LPA ₃ signaling at the embryo‐epithelial boundary controls decidualization pathways

44 citations , June 2017 in “The EMBO Journal”

LPA3 signaling in the uterus is crucial for placental formation and fetal development.

research HB-EGF Improves the Hair Regenerative Potential of Adipose-Derived Stem Cells via ROS Generation and Hck Phosphorylation

20 citations , December 2019 in “International Journal of Molecular Sciences”

HB-EGF boosts the hair growth ability of stem cells, making it a potential hair loss treatment.

research Preparation of highly-concentrated autologous platelet-rich plasma for biomedical use

14 citations , April 2019 in “The Ukrainian Biochemical Journal”

A simple method was developed to prepare concentrated platelet-rich plasma for use in healing and tissue repair.

research Sustained Postnatal Skin Regeneration Upon Prenatal Application of Functionalized Collagen Scaffolds

8 citations , November 2019 in “Tissue Engineering Part A”

Functionalized collagen scaffolds applied prenatally greatly improve skin regeneration.

Inhalation Therapy for Repairing Damaged Elastin Fibers and Decelerating Elastinolysis in Chronic Obstructive Pulmonary Disease

research Inhalation therapy for repairing damaged elastin fibers and decelerating elastinolysis in chronic obstructive pulmonary disease

8 citations , March 2018 in “Expert Review of Respiratory Medicine”

Inhalation therapy may repair and protect elastin in the lungs of COPD patients.

research Lipodermatosclerosis: a postphiebitic syndrome

8 citations , December 1997 in “International Journal of Dermatology”

The patient has a leg condition caused by vein issues, needing lifestyle changes and leg care.

research Arachidonate 12-Lipoxygenase Inhibitors Promote S100A3 Citrullination in Cultured SW480 Cells and Isolated Hair Follicles

4 citations , January 2017 in “Biological & pharmaceutical bulletin”

Inhibiting ALOX12 can help hair cuticle maturation by increasing S100A3 citrullination.

research Production of GJycosaminoglycans by Rat Hair Follicle Cells in Vitro

4 citations , May 1981 in “Australian Journal of Biological Sciences”

Rat hair follicle cells can produce and release various glycosaminoglycans over time.

research An epidermis‐permeable dipeptide is a potential cosmetic ingredient with partial agonist/antagonist activity toward fibroblast growth factor receptors

3 citations , May 2019 in “Journal of Cosmetic Dermatology”

Pro-Ile could be used in cosmetics to improve skin, hair growth, and healing.

research Dermatology, ed. 2

3 citations , May 1985 in “Journal of The American Academy of Dermatology”

The book "Dermatology" has useful content but some sections lack detail and accuracy; it's recommended for dermatologists to review before buying.