January 2004 in “Analytical Sciences: X-ray Structure Analysis Online” The document explains how to make a compound called 3.BETA.-Benzoyloxy-4-pregnen-16.ALPHA.,17.ALPHA.-epoxy-6,20-dione and describes its crystal structure.
15 citations
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April 2008 in “Steroids” The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.
59 citations
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January 2015 in “Nanoscale” The new micelle formulation delivers acne treatment more effectively and safely than current gels.
14 citations
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June 2011 in “Steroids” New compounds may help treat prostate issues without affecting androgen receptors.
18 citations
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June 1998 in “Circulation” Mild essential fatty acid deficiency can cause health issues and is worsened by low-fat diets.
7 citations
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April 2019 in “The Journal of Steroid Biochemistry and Molecular Biology” 11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
1 citations
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December 2019 in “Journal of medicine and life science” Docosahexaenoic acid (DHA) may help hair growth by promoting dermal papilla cell proliferation.
7 citations
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December 1971 in “European Journal of Endocrinology” Human hair follicles can process steroid hormones like DHEA.
January 2025 in “Cellular & Molecular Biology Letters” Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.
January 2025 in “International Journal of Advanced Biochemistry Research” Alpha linolenic acid and linoleic acid help treat inflammatory skin conditions in dogs.
109 citations
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April 1997 in “Journal of Lipid Research” Linoleate deficiency in rats reduces growth and n-6 polyunsaturate accumulation, causing mild symptoms.
January 2002 in “Chinese Journal of Pharmaceuticals” A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.
8 citations
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July 2018 in “Analytical sciences” Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.
Linoleic acid is essential for healthy skin, and while deficiency is rare in Western societies, it can cause dry, scaly skin and hair loss.
7 citations
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May 2016 in “European Polymer Journal” The new nanocarriers improve how well water-insoluble drugs dissolve and allow for controlled drug release.
January 2006 in “Benzina: Revista d'excepcions culturals” Trienones are more effective at inhibiting the enzyme linked to hair loss than dienones.
April 1992 in “Current opinion in therapeutic patents” New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.
9 citations
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February 2004 in “Veterinary Dermatology” Canine hair follicle cells metabolize DHEA and testosterone differently than human cells.
August 2013 in “日本医療薬学会年会講演要旨集” Hair contains complex lipids, including cholesterol and fatty acids, similar to skin.
73 citations
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July 1977 in “Archives of Dermatology” Applying safflower oil to the skin reversed fatty acid deficiency symptoms in 21 days.
64 citations
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March 1984 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The hexosamine pathway helps maintain healthy skin by affecting the skin's structure and possibly increasing hair follicle stem cells.
94 citations
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July 1991 in “Clinical endocrinology” Cyproterone acetate at 2mg daily is as effective as higher doses for treating excessive hair growth in women.
40 citations
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July 2019 in “Journal of Investigative Dermatology” Lack of a key enzyme causes severe skin issues and death in mice.
June 2024 in “ChemBioChem” Replenishing free 18-MEA can help restore damaged hair surfaces.
January 2007 in “Journal of Clinical Dermatology” The topical solution increased hair count but wasn't significantly better than placebo in other measures.
7 citations
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January 1971 in “Archives of Dermatological Research” 37 citations
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January 1986 in “Carcinogenesis” ODC expression in mouse skin and tumors is varied and can be inhibited by retinoic acid or cycloheximide.
April 2016 in “Annals of laboratory medicine” The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.
21 citations
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January 2010 in “JOURNAL OF HEALTH SCIENCE” Abietic acid from pine resin can effectively inhibit testosterone 5α-reductase.