research Game Changers: Blockbuster Small-Molecule Drugs Approved by the FDA in 2024
In 2024, the FDA approved 27 innovative small-molecule drugs, with many offering significant treatment improvements.
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120-150 / 344 resultsresearch Mathematical Modeling and Inference of Epidermal Growth Factor-Induced Mitogen-Activated Protein Kinase Cell Signaling Pathways
Mathematical modeling helps understand and predict the MAPK cell signaling pathway.
research Leveraging nature’s nanocarriers: Translating insights from extracellular vesicles to biomimetic synthetic vesicles for biomedical applications
Biomimetic synthetic vesicles could improve precision medicine by combining natural and synthetic benefits.
research Beyond Wavy Hairs
EGFR signaling is crucial for skin and hair health, and targeting it could help treat skin diseases and cancer.
research CDK4/6 inhibition mitigates stem cell damage in a novel model for taxane‐induced alopecia
CDK4/6 inhibitors can protect hair cells from chemotherapy damage.
research The Cutaneous Epidermal Growth Factor Network: Can it be Translated Clinically to Stimulate Hair Growth?
Understanding EGFR roles could lead to new hair loss treatments.
research The role of WNT10B in physiology and disease: A 10-year update
WNT10B is important for body functions and linked to diseases like osteoporosis, obesity, and cancer.
research Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time
Advanced imaging methods have improved understanding of cancer cell interactions and treatment strategies.
research Enzyme Inhibitors from Gorgonians and Soft Corals
Marine compounds from gorgonians and soft corals show promise for drug development, especially for chronic disorders.
research Genetic Variation in CYP2B6, UGT1A4 and Sulfotransferases Is Associated with Disease-Free Survival in South African Breast Cancer Patients Treated with Tamoxifen
Genetic differences affect breast cancer treatment success with tamoxifen in South African patients.
research Molecular mechanisms of asymmetric divisions in mammary stem cells
Disruptions in mammary stem cell division can lead to cancer, but targeting these processes might help treat breast cancer.
research EGFR Inhibitors and Cutaneous Complications: A Practical Approach to Management
The document provides advice on how to recognize and treat skin-related side effects of cancer drugs known as EGFR inhibitors.
research Redefining hormone resistance in prostate cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research Pegylated Liposomal Doxorubicin in the Treatment of Breast Cancer
PLD is an effective and safer alternative for treating breast cancer.
research Supportive Oncodermatology: Addressing dermatologic adverse events associated with oncologic therapies
Cancer survivors often experience worse skin problems from treatment than expected, and working with dermatologists could help improve their condition.
research Sacituzumab tirumotecan (sac-TMT/MK-2870/SKB264): a novel antibody–drug conjugate in breast cancer
Sacituzumab tirumotecan shows promise in treating breast cancer with manageable side effects.
research The incidence and management of cutaneous adverse events of the epidermal growth factor receptor inhibitors
EGFR inhibitors can cause various skin issues during cancer treatment, and managing these is important for patient care.
research Nanoparticles in Cancer Treatment: A Narrative Review
Nanoparticles improve cancer treatment by reducing side effects and targeting cancer cells better.
research ОСОБЕННОСТИ ДИНАМИКИ ПАРАМЕТРОВ НОСОВОГО ДЫХАНИЯ У ДЕТЕЙ С АДЕНОИДИТОМ
Measuring nasal breathing changes helps evaluate adenoiditis treatment in children.
research ЭКОЛОГИЧЕСКАЯ ТРИАДА ФАКТОРОВ ЗДОРОВЬЯ ЧЕЛОВЕКА: НЕГАТИВНЫЙ СОЧЕТАННЫЙ ЭФФЕКТ ФИЗИЧЕСКОЙ АКТИВНОСТИ, МАЛОПОДВИЖНОГО ПОВЕДЕНИЯ И COVID-19
Physical activity increased, but sedentary behavior also rose, especially in men.
research ТРАВМАТИЗАЦИЯ СЛИЗИСТОЙ ОБОЛОЧКИ ПЕРЕГОРОДКИ НОСА КРЫС ИЗМЕНЯЕТ ПОВЕДЕНИЕ И БАЛАНС ВЕГЕТАТИВНОЙ НЕРВНОЙ СИСТЕМЫ.
Nasal septum injury in rats changes behavior and affects the nervous system.
research ОСТРЫЙ ПОСТОПЕРАЦИОННЫЙ БОЛЕВОЙ СИНДРОМ У ПАЦИЕНТОВ РИНОХИРУРГИЧЕСКОГО ПРОФИЛЯ ПОСЛЕ ИСПОЛЬЗОВАНИЯ ПОПУЛЯРНЫХ МЕТОДОВ АНЕСТЕЗИИ В Г. МОСКВЕ.
The anesthesia protocol with fentanyl and propofol caused the least pain during septoplasty.
research МОДЕЛИРОВАНИЕ РИНОХИРУРГИЧЕСКИХ ВМЕШАТЕЛЬСТВ У КРЫС: ЭКСПРЕССИЯ БЕЛКА Р53 И ФОРМИРОВАНИЕ ТЕМНЫХ НЕЙРОНОВ В ГИППОКАМПЕ
p53 protein may help protect or kill neurons under stress.
research МИКРОБИОЦЕНОЗ ЛУНОК УДАЛЕННЫХ ЗУБОВ У ПАЦИЕНТОВ С АЛЬВЕОЛИТОМ
The collagen sponge with lincomycin heals tooth sockets faster and reduces infection better than iodoform gauze.
research КАЧЕСТВО ЖИЗНИ И ПСИХИЧЕСКОЕ ЗДОРОВЬЕ ПАЦИЕНТОВ ПОСЛЕ ЧЕРЕПНО-МОЗГОВОЙ ТРАВМЫ
Patients with traumatic brain injury need comprehensive care to improve their well-being.
research The impact of exercise on tolerability of systemic treatment in metastatic colorectal cancer: A literature review
Exercise may help reduce treatment side effects and improve survival in metastatic colorectal cancer.
research The pharmacovigilance analysis of adverse events of erlotinib based on the open access FAERS database
Erlotinib can cause unexpected side effects like eyelash growth and scarring.
research ЭКСПЕРИМЕНТАЛЬНОЕ ВОСПАЛЕНИЕ ПОСЛЕ ХИРУРГИЧЕСКОЙ ТРАВМАТИЗАЦИИ ПЕРЕГОРОДКИ НОСА И ДИСБАЛАНС ВЕГЕТАТИВНОЙ НЕРВОНОЙ СИСТЕМЫ
Inflammation from nasal surgery temporarily increases sympathetic nervous system activity, but balance is restored within a week.
research БИОРИТМЫ И ИХ ВОЗДЕЙСТВИЕ НА ПСИХОЭМОЦИОНАЛЬНОЕ СОСТОЯНИЕ СТУДЕНТОВ ВО ВРЕМЯ ДИСТАНЦИОННОЙ И ОЧНОЙ ФОРМ ОБУЧЕНИЯ
Online classes worsened students' emotional state, but returning to full-time classes made it worse.
research SYSTEM ANALYSIS OF MECHANISMS OF EFFECT OF ESSENTIAL OILS
Essential oils can boost athletic performance by improving brain function and muscle relaxation.