37 citations
,
January 2009 in “Sexual Development” Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.
31 citations
,
January 1995 in “The American journal of medicine” Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.
29 citations
,
January 2006 in “Clinical chemistry and laboratory medicine” SHBG binding properties are unchanged in male liver cirrhosis patients.
24 citations
,
June 2011 in “International Journal of Dermatology” Most pregnant women experience skin changes like darkening and itching, while serious skin conditions are rare but need early treatment.
4 citations
,
December 2014 in “PubMed” Pre-operative hormone treatment for hypospadias surgery might improve outcomes, but more research is needed to confirm.
January 2023 in “Pediatric Endocrinology Diabetes and Metabolism” Isolated pubic hair in infants is usually harmless and resolves on its own.
393 citations
,
November 2000 in “Archives of General Psychiatry” Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.
130 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
45 citations
,
January 2020 in “International Journal of Molecular Sciences” Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.
28 citations
,
May 2015 in “Addiction Biology” Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.
27 citations
,
January 2020 in “Experimental Dermatology” Immune cells affect hair growth and could lead to new hair loss treatments.
18 citations
,
July 2010 in “Expert Review of Endocrinology & Metabolism” The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.
3 citations
,
October 2010 in “Epilepsy Currents” Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.
July 2015 in “Cambridge University Press eBooks” Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.
January 2006 in “Advances in developmental biology” The Hairless gene is crucial for healthy skin and hair growth.
16 citations
,
February 2016 in “Gynecological Endocrinology” Indian women with PCOS from Delhi and Srinagar show different symptoms, with Delhi women having higher obesity and blood sugar issues, and Srinagar women showing more hair growth and testosterone levels.
Certain gut bacteria may protect against or increase the risk of hair loss.
February 2025 in “Chemico-Biological Interactions” 5-Fluorouracil causes hair loss by blocking signals needed for hair growth.
11 citations
,
February 2023 in “British Journal of Pharmacology” Isoxazole 9 (ISX9) may help regrow hair by activating certain cell signals.
January 2025 in “Dermatologic Therapy” Oxidative stress damages hair follicles and worsens hair loss in androgenetic alopecia.
June 2024 in “Skin Research and Technology” Red fluorescence in AGA scalps is linked to different microbes.
8 citations
,
November 2024 in “Phytomedicine” Isoquercitrin helps hair grow by activating certain cell processes.
104 citations
,
June 2020 in “Journal of Endocrinology” Hyperandrogenism and insulin resistance in PCOS-like rats can lead to pregnancy complications due to increased cell death in the uterus and placenta.
36 citations
,
October 2021 in “Frontiers in Endocrinology” Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
12 citations
,
April 2020 in “British Journal of Dermatology” Caffeine may help reduce stress-induced hair loss.
March 2026 in “Zenodo (CERN European Organization for Nuclear Research)” Restoring communication in hair follicle networks may treat hair loss and improve sexual dysfunction.
February 2026 in “Cosmetics” Milk-derived exosomes may help treat hair loss by boosting hair follicle growth.
August 2025 in “Bioactive Materials” Ac-GFFY-IGF peptide is a promising, safe, and effective treatment for hair loss, better than current options.
July 2025 in “Reproductive Biology and Endocrinology” Early androgen exposure affects hormone receptor expression in adult female rats' brains, but not in males.
Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.