research Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
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30-60 / 1000+ results research Enhancing therapeutic efficacy of human adipose-derived stem cells by modulating photoreceptor expression for advanced wound healing
Green OLED light improves stem cell effectiveness for better wound healing.
research Recent advances in electrospun nanofibers for wound healing
New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.
research Regulatory roles of androgens in cutaneous wound healing
Testosterone may slow down wound healing and increase inflammation.
research 870 Y27632 promotes proliferation via EGFR signaling in a newly isolated and characterized human primary sebocyte cell line
Y27632 increases cell growth through EGFR signaling, not ROCK1/2.
research Spatiotemporal regulation of acute wound healing by the NLRP3 inflammasome: dual roles in macrophage-fibroblast chemotaxis and phenotype during wound repair
NLRP3 helps control inflammation and repair in wound healing, making it a potential target for treatment.
research Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration
IL-1 promotes fat cell growth in skin, while WNT inhibits it and encourages scar formation.
research Clinical Snippets
Glycerol may improve wound healing and prevent keloids, a device can measure itch intensity, male pattern baldness is highly heritable, and fumaric acid esters may work for psoriasis by causing cell death in T cells.
research Prediction and Demonstration of Retinoic Acid Receptor Agonist Ch55 as an Antifibrotic Agent in the Dermis
Ch55 may help reduce skin scarring and fibrosis.
research Exosomes for Aesthetic Dermatology: A Comprehensive Literature Review and Update
Exosomes may help with hair growth and scar healing, but more research is needed.
research [Retracted] Fibroblasts in Scar Formation: Biology and Clinical Translation
Fibroblasts are crucial in scar formation and wound healing, with potential therapies aiming for scarless healing.
research Evaluation of the Treatment Effect of Aloe vera Fermentation in Burn Injury Healing Using a Rat Model
Aloe vera fermentation helps heal burns faster by reducing inflammation and changing gut bacteria.
research Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions
New effective scar treatments are urgently needed due to the current options' limited success.
research Fibroblasts and wound healing: an update
Understanding different types of skin cells, especially fibroblasts, can lead to better treatments for wound healing and less scarring.
research A Prospective interventional study on the therapeutic potential of human placental extract in dermatological conditions.
Human placental extract effectively and safely improves melasma, ulcers, and alopecia areata.
research The HEDGEHOG-GLI1 pathway is important for fibroproliferative properties in keloids and as a candidate therapeutic target
Targeting the HEDGEHOG-GLI1 pathway could help treat keloids.
research Bioinformatics analysis and verification of m6A related genes based on the construction of keloid diagnostic model
IGF2BP3 gene is up-regulated in keloid patients, suggesting potential targets for treatment.
research A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis
Immune cells are essential for early hair and skin development and healing.
research Effects of Fibroblast Transplantation on the Content of Macrophages and the Morphology of Regenerating Ischemic Cutaneous Wounds
Fibroblast transplantation improves wound healing, with dermal equivalents slightly enhancing skin regeneration.
research Recent Understandings of Biology, Prophylaxis and Treatment Strategies for Hypertrophic Scars and Keloids
The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.
research Bioregenerative Applications of the Human Mesenchymal Stem Cell- Derived Secretome: Part-II
The mesenchymal stem cell secretome may effectively treat various diseases as an alternative to traditional stem cell therapies.
research TNC+ fibroblasts involve in skin inflammation via neuro-immune and interacting with T cells
TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.
research Dermal fibroblasts in the focus of modern cosmetology: aging and response to cosmetic procedures: A review
Understanding fibroblasts helps improve cosmetic treatments for aging skin.
research A nude mouse model of hypertrophic scar shows morphologic and histologic characteristics of human hypertrophic scar
Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
research A guide to studying human dermal adipocytes in situ
The guide explains how to study human skin fat cells and their tissue, aiming to improve research and medical treatments.
research Early Dengue Virus Infection in Human Skin: A Cycle of Inflammation and Infectivity
Chicken feather gene mutation helps understand human hair disorders.
research Anagen hair follicles transplanted into mature human scars remodel fibrotic tissue
Transplanting growing hair follicles into scars can help regenerate and improve scar tissue.
research Comparison of intralesional triamcinolone acetonide alone and with 5 -fluorouracil for the treatment of keloids
research Effects of non-ablative fractional erbium glass laser treatment on gene regulation in human three-dimensional skin models
Erbium glass laser treatment may help with skin remodeling, reduce inflammation, and improve skin cell maturation.
research Pathophysiology of the Burn Scar
Burn scars heal abnormally and more research is needed to find better treatments.