research Engineered extracellular vesicles for tissue repair and regeneration
Engineered extracellular vesicles can improve tissue repair and regeneration.
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210-240 / 1000+ resultsresearch What's new in the pathogeneses and triggering factors of bullous pemphigoid
Bullous pemphigoid is influenced by genetic factors, immune cell dysfunction, aging, and triggers, with treatment often improving symptoms.
research Keratin intermediate filaments in the colon: guardians of epithelial homeostasis
Keratin proteins are essential for keeping the cells in the human colon healthy and stable.
research Regulatory T cells in dominant immunologic tolerance
Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
research Bioengineered Skin Intended as In Vitro Model for Pharmacosmetics, Skin Disease Study and Environmental Skin Impact Analysis
Bioengineered skin models help reduce animal testing and advance research in cosmetics and skin disease.
research Alopecia Areata: Pathogenesis, Diagnosis, and Therapies
Alopecia areata causes unpredictable hair loss, and more research is needed to fully understand and treat it effectively.
research Swellable Microneedles in Drug Delivery and Diagnostics
Swellable microneedles could improve drug delivery and diagnostics but need more research on materials and technology integration.
research Colchicine in Managing Skin Conditions: A Systematic Review
Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.
research Cutaneous Lesions in the Rat Following Administration of an Irreversible Inhibitor of erbB Receptors, Including the Epidermal Growth Factor Receptor
CI-1033 causes skin lesions in rats, similar to humans, due to EGF receptor inhibition.
research Merkel cell carcinoma: updates in tumor biology, emerging therapies, and preclinical models
New therapies and trials are needed for Merkel cell carcinoma, a tough skin cancer.
research Engineered Hair Follicle Mesenchymal Stem Cells Overexpressing Controlled-Release Insulin Reverse Hyperglycemia in Mice with Type l Diabetes
Genetically modified stem cells from human hair follicles can lower blood sugar and increase survival in diabetic mice.
research Epigenetic regulation and factors that influence the effect of iPSCs-derived neural stem/progenitor cells (NS/PCs) in the treatment of spinal cord injury
Epigenetic factors affect the success of using iPSC-derived cells for spinal cord injury treatment.
research A hybrid hydrogel encapsulating human umbilical cord mesenchymal stem cells enhances diabetic wound healing
A new hydrogel with stem cells from the human umbilical cord speeds up healing in diabetic wounds.
research Pathological Mechanisms Involved in Epidermolysis Bullosa Simplex: Current Knowledge and Therapeutic Perspectives
Promising treatments for EBS include anti-inflammatory drugs, antibiotics, creams, mTOR inhibitors, and gene editing, but more trials are needed.
research Proteolysis‐Targeting Chimera (PROTAC): Current Applications and Future Directions
PROTACs offer new ways to treat hard-to-target diseases, with promising drugs for cancer in advanced trials.
research Hydrogels Modulating the Microbiome: Therapies for Tissue Regeneration with Infection Control
Functionalized hydrogels can help heal tissues and fight infections by delivering beneficial bacteria and antimicrobials.
research Game Changers: Blockbuster Small-Molecule Drugs Approved by the FDA in 2024
In 2024, the FDA approved 27 innovative small-molecule drugs, with many offering significant treatment improvements.
research Extracellular Vesicles as Surrogates for Drug Metabolism and Clearance: Promise vs. Reality
Extracellular vesicles could help tailor drug treatments, but more research is needed.
research Efficient Gene Editing for Heart Disease via ELIP-Based CRISPR Delivery System
ELIP-based CRISPR delivery improves heart disease gene editing but needs more testing.
research Dupilumab in the treatment of severe atopic dermatitis refractory to systemic immunosuppression: case report
Dupilumab improved severe atopic dermatitis in a patient who didn't respond to other treatments.
research Pharmacological Activity of Cepharanthine
Cepharanthine has many medicinal uses but needs improvement for better effectiveness.
research Disease-related biomarkers as experimental endpoints in 3D skin culture models
research Cytokine Engineering Approaches for Regenerative Medicine
Engineered cytokines show promise for improving tissue healing and safety in regenerative medicine.
research Wounds and the Microbiota: The Healing Interplay Between Host and Microbial Communities
Balancing good and harmful microbes is key to healing chronic wounds.
research Phenotyping mice with skin, hair, or nail abnormalities: A systematic approach and methodologies from simple to complex
Understanding genetic variations in mice is crucial for studying skin, hair, or nail abnormalities.
research Effects of natural products on skin inflammation caused by abnormal hormones secreted by the adrenal gland
Natural products may help treat skin inflammation from abnormal adrenal hormones.
research Study of the Thyroid Profile of Patients with Alopecia
People with hair loss conditions may also have thyroid disorders, but more research is needed to understand the connection.
research AIRE Deficiency Leads to the Development of Alopecia Areata‒Like Lesions in Mice
AIRE deficiency causes hair loss similar to alopecia areata in mice.
research Biologics and Small Molecules for Inflammatory Nail Disorders: A Narrative Review
Biologics and small molecules can effectively treat inflammatory nail disorders, but personalized treatment plans are important.
research Interleukin-15 is a hair follicle immune privilege guardian
Interleukin-15 can help hair growth and protect hair follicles.