Minoxidil and finasteride are the only FDA-approved treatments for hair loss caused by genetic and hormonal factors, but their effectiveness is often doubted, indicating a need for new treatments.
January 2020 in “Indian Journal of Pharmaceutical Sciences” Natural products show promise for new hair loss treatments.
23 citations
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June 2015 in “Experimental Dermatology” Pericytes can both help and hinder wound healing, needing more research for effective use in treatments.
110 citations
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August 2011 in “Journal of Visualized Experiments” 3D skin models better mimic human skin and melanoma progression than older methods.
52 citations
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January 2021 in “Journal of Thoracic Oncology” Effective vaccines and treatments are crucial for long-term COVID-19 control.
51 citations
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January 2024 in “Burns & Trauma” Engineered extracellular vesicles can improve tissue repair and regeneration.
25 citations
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November 2020 in “Cell Reports Medicine” Developing human skin has immune cells with memory-like features.
17 citations
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May 2025 in “MedComm” Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
17 citations
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July 2024 in “Frontiers in Oncology” New therapies and trials are needed for Merkel cell carcinoma, a tough skin cancer.
17 citations
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January 2023 in “Frontiers in Cell and Developmental Biology” iPSCs are promising for studying and treating COVID-19.
13 citations
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February 2024 in “Clinical Epigenetics” Epigenetic factors affect the success of using iPSC-derived cells for spinal cord injury treatment.
8 citations
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July 2025 in “Gels” Functionalized hydrogels can help heal tissues and fight infections by delivering beneficial bacteria and antimicrobials.
6 citations
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February 2024 in “Pharmaceutics” ELIP-based CRISPR delivery improves heart disease gene editing but needs more testing.
2 citations
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May 2023 in “Frontiers in Pharmacology” Natural products may help treat skin inflammation from abnormal adrenal hormones.
February 2026 in “Biomedicines” Nanotechnology offers promising new treatments for hair loss by improving targeted delivery and addressing key causes.
January 2026 in “Preprints.org” Nanotechnology shows promise for treating hair loss but faces safety and approval challenges.
March 2025 in “Nature Communications” NSC167409 can effectively inhibit the virus causing hand, foot, and mouth disease.
November 2024 in “Burns & Trauma” Skin organoids help improve wound healing and tissue repair.
June 2022 in “Authorea (Authorea)” Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.
51 citations
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January 1997 in “PubMed” GABEB is a less severe skin condition caused by a gene mutation affecting collagen, leading to blisters and other symptoms.
7 citations
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August 2023 in “Life” Extracellular vesicles could help tailor drug treatments, but more research is needed.
69 citations
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January 2021 in “Journal of Biological Chemistry” Plant-derived amino acids can help develop new antimicrobial drugs.
489 citations
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November 2021 in “Signal Transduction and Targeted Therapy” The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
378 citations
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February 2020 in “Nature Reviews Endocrinology” 278 citations
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May 2013 in “Ca” Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.
227 citations
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April 2020 in “Cell” More precise, personalized therapies are needed for autoimmune diseases.
195 citations
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December 2009 in “Journal of Investigative Dermatology” Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.
194 citations
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October 2018 in “Microbiome” Acne is linked to complex skin microbe interactions, and new findings suggest microbiome-based treatments could be effective.
134 citations
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July 2020 in “Experimental dermatology” Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
132 citations
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June 2016 in “Cell and Tissue Research” The right cells and signals can potentially lead to scarless wound healing, with a mix of natural and external wound healing controllers possibly being the best way to achieve this.