research New steps forward in the neuroactive steroid field
Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
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research Regulatory T cells modulate bone marrow stromal cell osteogenesis by activating ROCK-myosin axis and cell contractility
Regulatory T cells enhance bone formation by influencing cell mechanics.
research ANTI-CD19 MONOCLONAL ANTIBODY FOR SYSTEMIC LUPUS ERYTHEMATOSUS AND NEUROMYELITIS OPTICA SPECTRUM DISORDER
Anti-CD19 therapy may help treat SLE and NMOSD.
research Alopecia
The document concludes that alopecia has significant social and psychological effects, leading to a market for hair loss treatments.
research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
research Calreticulin: non‐endoplasmic reticulum functions in physiology and disease
Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
research Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion
The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
research Signal integrator function of CXXC5 in Cancer
CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
research Aberrant Activation of the Hedgehog Pathway in Cutaneous Melanoma: Therapeutic Potential of Pharmacological Inhibitors
Hedgehog pathway inhibitors could be effective in treating melanoma.
research Proteome Analysis of Alpine Merino Sheep Skin Reveals New Insights into the Mechanisms Involved in Regulating Wool Fiber Diameter
Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.
research A preview of selected articles
The document concludes that DNA methylation and the mTOR pathway are important for stem cell function and could impact disease treatment.
research Exosomes in stroke management: A promising paradigm shift in stroke therapy
Exosome therapy could revolutionize stroke treatment, but more research is needed for human use.
research Lysophosphatidic acid increases the proliferation and migration of adipose-derived stem cells via the generation of reactive oxygen species
Lysophosphatidic acid boosts stem cell growth and movement by creating reactive oxygen species.
research Engineering strategies to enhance the research progress of mesenchymal stem cells in wound healing
Engineering strategies improve stem cells' ability to heal wounds effectively.
research Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regression
A specific signal from hair cells controls the tightening of the surrounding muscle, which is necessary for hair shedding.
research The role of Atg5 gene in tumorigenesis under autophagy deficiency conditions
Atg5 can promote tumors when autophagy is deficient but suppresses them under normal conditions.
research Sex hormone supplementation improves breathing and restores respiratory neuroplasticity following C2 hemisection in rats
Sex hormone supplements help improve breathing and nerve recovery after spinal injury in rats.
research 3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline
Perhexiline can effectively target ovarian cancer cells left after treatment.
research Succinic Acid in Cosmetics and Aesthetic Dermatology: Biological Roles and Applications
Succinic acid helps improve skin conditions like acne and rosacea.
research 1496 Transcription factor SOX2-induced amphiregulin inhibits pressure ulcer formation via suppressing oxidative stress after cutaneous ischemia-reperfusion in mice
SOX2 helps reduce wound size and pressure ulcer formation by suppressing oxidative stress and increasing antioxidant activity in mice.
research Cellular and Molecular Mechanisms of Wound Repair: From Biology to Therapeutic Innovation
Advancements in wound healing aim to improve personalized treatments and enhance healing outcomes.
research Drug repurposing: A novel strategy to target cancer stem cells and therapeutic resistance
Repurposing existing drugs and using micronutrients may effectively target cancer stem cells and improve cancer treatment.
research Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions
IL-25 helps heal diabetic wounds by improving blood vessel and skin cell functions.
research Effect of composite biodegradable biomaterials on wound healing in diabetes
Composite biodegradable biomaterials can improve diabetic wound healing but need more development for clinical use.
research Fibroblasts and endothelial cells interplay drives hypertrophic scar formation: Insights from in vitro and in vivo models
Fibroblast and endothelial cell interactions are crucial in forming hypertrophic scars.
research Hedgehog Pathway Inhibitors against Tumor Microenvironment
Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.
research Activation of mitochondrial aldehyde dehydrogenase 2 promotes hair growth in human hair follicles
Activating ALDH2 can boost hair growth.
research Dexpanthenol ameliorates lipopolysaccharide-induced cardiovascular toxicity by regulating the IL-6/HIF1α/VEGF pathway
Dexpanthenol helps protect the heart from damage by reducing inflammation and stress.
research Cold Plasma An emerging technology for clinical use in wound healing
Cold Plasma shows promise for healing wounds by killing bacteria and helping tissue grow.
research Exosome-based cell therapy for diabetic foot ulcers: Present and prospect
Exosomes show promise for healing diabetic foot ulcers.