14 citations
,
November 2014 in “European journal of medicinal chemistry” Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
14 citations
,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.
13 citations
,
November 2014 in “Toxicology Letters” Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.
11 citations
,
December 2018 in “Assay and Drug Development Technologies” Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
11 citations
,
March 2009 in “Bioorganic & Medicinal Chemistry Letters” Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.
10 citations
,
May 2010 in “Analytica Chimica Acta” New tests detect finasteride and dutasteride in urine quickly and easily.
8 citations
,
October 2020 in “Pharmaceutics” Dutasteride-loaded nanoparticles coated with Lauric Acid-Chitosan show promise for treating hair loss due to their controlled release, low toxicity, and potential to stimulate hair growth.
8 citations
,
October 1998 in “Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology” Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.
5 citations
,
May 2025 in “Scientific Reports” Phyllanthus emblica leaves show potential for developing new antimalarial drugs with low toxicity.
5 citations
,
January 2005 in “Journal of Enzyme Inhibition and Medicinal Chemistry” New steroids were effective in blocking male hormone receptors in hamster prostates.
5 citations
,
February 1997 in “Bioorganic & Medicinal Chemistry” New compounds were made that effectively block a specific enzyme related to androgen conditions.
3 citations
,
December 2021 in “Journal of medicinal plants” Halocnemum strobilaceum has potential health benefits and uses, including anticancer and antimicrobial properties.
3 citations
,
September 2016 in “Natural Product Communications” Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.
3 citations
,
August 2014 in “Steroids” Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.
2 citations
,
March 2021 in “Journal of Cosmetic Dermatology” Umbilical cord-derived media is safe and effective for hair growth.
2 citations
,
November 2018 in “Indian Journal of Pharmaceutical Education” The developed model can predict effective 5-alpha-reductase enzyme inhibitors.
1 citations
,
January 2023 in “Bioscience Journal” Sorafenib and Platycladus orientalis leaf extract together effectively suppress cervical cancer cell growth.
1 citations
,
April 2018 in “Journal of Investigative Dermatology” Tofacitinib helped most patients with alopecia areata regrow hair and changes in immune cells were linked to the treatment's effectiveness.
1 citations
,
April 2017 in “Journal of Investigative Dermatology” SM04554 may increase hair growth as a topical treatment for androgenetic alopecia.
1 citations
,
May 2016 in “Pharmaceutical Biology” Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.
November 2025 in “Frontiers in Oncology” Sphaeranthus indicus and silver nanoparticles can help treat liver cancer by killing cancer cells.
November 2025 in “Discover Pharmaceutical Sciences” The essential oils nanoemulsion promotes hair growth better than 2% minoxidil in mice.
New peptides can delay aging and improve cell function.
December 2024 in “International Journal of Drug Delivery Technology” The new delivery method for dutasteride is more effective and has fewer side effects.
February 2024 in “Bangladesh pharmaceutical journal” The herbal hair oil increased hair growth and reduced hair fall for most users without significant side effects.
Different amounts of propylene glycol change the thickness of katuk leaf hair tonic.
August 2023 in “The Indonesian Biomedical Journal” Rosemary essential oil improved hair growth and thickness in UVB-exposed mice.
April 2018 in “Journal of Ayurveda and integrative medicine” Ayurvedic treatment improved hair growth in a person with hair loss.
April 2017 in “Journal of Investigative Dermatology” SM04755 may be an effective topical treatment for psoriasis.
April 2017 in “Journal of Investigative Dermatology” SIG-1451 could be a promising new treatment for atopic dermatitis.