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research Intermittent Use of Testosterone Inactivating Pharmaceuticals Using Finasteride Prolongs the Time Off Period
Using finasteride with TIP extends time off period for prostate cancer patients.
research Platelet-rich fibrin in the management of oral mucosal lesions: a scoping review
Platelet-rich fibrin shows promise for treating oral lesions but needs more research.
research Variables affecting the potential efficacy of PRP in providing chronic pain relief
Standardizing PRP preparation and application could improve its effectiveness for chronic pain relief.
research Treatment with injectable platelet-rich fibrin in a rat model of melasma
Injectable platelet-rich fibrin can safely and effectively treat melasma.
research Effects of supplementation with two probiotic strains (Lactobacillus helveticus and Bifidobacterium longum) on hormonal status, oxidative stress, and clinical symptoms in women with polycystic ovary syndrome: a randomized clinical trial
Probiotic supplements may help reduce inflammation and oxidative stress in women with PCOS.
research Efficacy of oral retinoids in treatment-resistant lichen planopilaris
Oral retinoids may help some patients with hard-to-treat lichen planopilaris, but more research is needed.
research THU0189 Safety of four treatment regimens in early rheumatoid arthritis
All four treatments for early rheumatoid arthritis had similar safety profiles.
research Ultra-low dose estradiol and dydrogesterone for the treatment of menopausal symptoms in a pooled, multi-ethnic population
The study evaluated the efficacy of an ultra-low dose combination of 0.5 mg estradiol and 0.25 mg dydrogesterone in alleviating vasomotor symptoms in a multi-ethnic population of 583 postmenopausal women from Europe and China. Participants were randomized to receive the treatment or a placebo for 12 weeks. Results showed a significant reduction in the number of hot flushes per day with the treatment compared to placebo, along with improvements in health-related quality of life, including psychological symptoms and vaginal dryness. The treatment was well tolerated, with no significant differences in serious adverse events or changes in body weight between the groups. The study concludes that this treatment is consistently effective for menopause-related symptoms across different ethnicities.
research PEGylated Flavonoid Aspasomes as a Brain-Targeted Nano-Vesicular Platform for Enhanced Neuroprotection in Stress-Induced Cognitive Dysfunction
PEGylated flavonoid Aspasomes improve brain protection and memory in stress-related disorders.
research A double blind, randomised, vehicle-controlled, safety and tolerance study of topical PSK 3841 solution at 5% administered twice daily over four weeks to healthy Caucasian males with androgenetic alopecia
research 690 Platelet activation during PRP preparation for therapeutic use
PRP preparation partially activates platelets, causing varied growth factor release.
research Ionizable Coenzyme‐Engineered Lipid/Fiber Microplexes Boost Ribosomal Translation to Improve mRNA Therapy for Degenerative Diseases
New lipid/fiber microplexes improve mRNA therapy for degenerative diseases by enhancing cell function and treatment effectiveness.
research Recipient Site Anesthesia and Hemostasis
Using tumescent anesthesia in hair restoration surgery is safe and effective for long-lasting scalp numbness and reducing bleeding.
research Pneumatic skin flattening (PSF): A novel technology for marked pain reduction in hair removal with high energy density lasers and IPLs
Pneumatic Skin Flattening (PSF) significantly reduces pain during laser and IPL hair removal.
research Comparative efficacy and safety of platelet-rich plasma (PRP), injectable platelet-rich fibrin (i-PRF) and concentrated growth factors (CGF) for female pattern hair loss (FPHL): a prospective multicenter randomized clinical trial
CGF and i-PRF are more effective and safer than PRP for treating female pattern hair loss.
research Застосування кріоконсервованої плаценти в комплексному лікуванні флегмон щелепно-лицевої локалізації
research The efficacy of topical prostaglandin analogs for hair loss: A systematic review and meta-analysis
Topical prostaglandin analogs may help with hair growth but more research is needed.
research Prevention of doxorubicin-induced alopedia by scalp hypothermia: relation to degree of cooling.
Cooling the scalp below 22°C before and during chemotherapy can help prevent hair loss.
research Plasma rico en plaquetas en pacientes con trasplante capilar. Revisión de la literatura
PRP may help improve hair transplant results.
research Plasma rico en plaquetas en pacientes con trasplante capilar. Revisión de la literatura
PRP may help improve hair transplant results.
research Interstitial pneumonia with autoimmune features: challenges and controversies
The document concludes that diagnosing and treating Interstitial Pneumonia with Autoimmune Features (IPAF) is challenging, needs a multidisciplinary approach, and further research for better diagnostic criteria and treatments. It also emphasizes regular checks for Connective Tissue Disease symptoms in all patients with Interstitial Lung Disease.
research Tolerability of Six Months Indirect Cold (Physical) Plasma Treatment of the Scalp for Hair Loss
Cold plasma treatment for hair loss was well tolerated and showed improvement in most patients.
research Topical fluocinolone acetonide acetate ointment in autosomal dominant congenital hypotrichosis
A hair growth ointment improved hair length in a family with a genetic hair growth condition.
research Pilot study: Autologous platelet‐rich plasma used in a topical cream for facial rejuvenation
Topical PRP cream may improve facial skin by boosting collagen.
research Topical medication instillation techniques for glaucoma
There is not enough evidence to know if different ways of putting in eye drops for glaucoma work better than others.
research Liver transplantation for propionic acidemia in children
Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.
research Fluticasone Propionate-loaded Black Cumin Oil NLCs with Dual Deposition/Permeation Capabilities for Enhanced Psoriasis Management
This study investigated the use of black cumin oil-based nanostructured lipid carriers (NLCs) to enhance the therapeutic effect of fluticasone propionate (FP) for psoriasis treatment. The optimized NLCs, characterized by a size of 171.3 nm and a zeta potential of -32.3 mV, demonstrated superior drug deposition in the skin and permeation compared to a marketed cream. In vivo tests on imiquimod-induced psoriatic mice showed a 77% improvement in the Psoriasis Area and Severity Index (PASI) score, along with significant reductions in IL-6 and IL-1α levels, indicating decreased inflammation. The study concluded that the black cumin oil-based NLC formulation provides better skin targeting, penetration, and anti-inflammatory effects than standard treatments.
research Fractional ablative CO2 laser and oral isotretinoin—A prospective randomized controlled split‐face trial comparing concurrent versus delayed laser treatment for acne scars
Concurrent laser and isotretinoin treatment improves acne scars more than delayed treatment.
research CUTANEOUS T-CELL LYMPHOMA
The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.