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Discoid lupus erythematosus involves immune activation and fibrosis around hair follicles, with shared pathways across humans, dogs, and mice, suggesting potential treatments for both humans and animals.

Potential therapeutic targets for scarring hair loss are identified.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Mouse hair follicle stem cells can help prevent Type 1 Diabetes.

Folate receptor β helps suppress the immune system in macrophages and affects cancer growth and hair health.

Langerhans cells are crucial for skin immunity and allergic reactions.

Older skin has higher cancer risk due to inflammation and stem cell issues.

RXRα is crucial for proper immune response and links diet to immune function.

Aging slows wound healing due to weaker cells and immune response.

OX40-targeted therapies may help treat skin diseases by reducing inflammation and balancing immune responses.

Nanoplastics can penetrate skin cells, triggering inflammation and immune responses.

Stem cells from fat improve dog wound healing better than standard treatment.

Hair follicle stem cells reduced hair loss and inflammation in mice with a condition similar to human alopecia.

A new skin disease in four Labrador retrievers responded well to immunosuppressive treatment.

Transplanted hair follicles can change and adapt to new areas of the body, with the immune system possibly playing a role in this adjustment.

The IGRA test effectively detects past SARS-CoV-2 exposure, especially using nucleocapsid peptides.

Different types of alopecia cause hair loss due to immune system issues, with some allowing regrowth and others causing permanent loss.

Urban air pollution worsens hair loss in alopecia areata by increasing immune response.

The protein CTCF is essential for skin development, maintaining hair follicles, and preventing inflammation.

Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.

Dermal sheath cells help heal wounds by showing both skin and connective tissue traits.

Staphylococcus aureus affects immune responses and skin cells in atopic dermatitis, suggesting new treatment targets.

Thioredoxin reductase 1 does not affect glucocorticoid receptor activity in hair follicle cells.

Certain genetic factors may contribute to frontal fibrosing alopecia in Brazil.

A300 membranes help skin heal faster by promoting cell growth and repair.

Targeting Vδ1+T-cells may help treat alopecia areata.

Type 3 Innate Lymphoid Cells help maintain skin health and balance, and are involved in skin diseases and healing.

IL-1 receptor absence in mice leads to skin cysts and changes in immune response after UVB exposure.

Plakophilin 1 helps control skin cell immune responses to prevent excessive inflammation.

Vitamin D and calcium are essential for effective wound healing.