9 citations
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November 2015 in “Plastic and reconstructive surgery/PSEF CD journals” Gene knockout mice developed scars similar to human hypertrophic scars, useful for studying scar progression.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Both induced and spontaneous AA lymphocytes can cause alopecia areata in mice.
April 2023 in “Medizinische Genetik” New research has found 14 genes linked to the risk of developing alopecia areata, improving understanding and treatment options.
August 2021 in “Journal of Investigative Dermatology” ILC1-like cells can cause alopecia areata by disrupting hair follicle immunity, suggesting a new treatment approach.
46 citations
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February 2016 in “Experimental Dermatology” Genes play a significant role in male-pattern baldness, and understanding them could lead to new treatments and insights into related health issues.
December 2025 in “Egyptian Journal of Basic and Applied Sciences” JAK1 gene variation may increase alopecia areata risk.
155 citations
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December 2002 in “Journal of Investigative Dermatology” Thyroid-related genes are active in skin cells and may affect autoimmune conditions.
January 2010 in “Journal of Animal Science” Transcutaneous vaccination using nanoparticles can enhance immune responses and reduce basal cell carcinomas.
Keratinocytes can reduce the survival of certain melanoma cells, suggesting new therapy paths.
10 citations
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November 2023 in “Science Immunology” Super-enhancers control CD25 expression in specific cell types, affecting immune function.
June 2005 in “Journal of Investigative Dermatology” A bull with a gene mutation was asymptomatic, synthetic retinoids cause hair loss, and new therapeutic targets were identified for skin diseases.
68 citations
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October 2008 in “Archives of dermatological research” Generalized vitiligo in Chinese patients is linked to other autoimmune diseases, especially in familial cases.
150 citations
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April 1997 in “Journal of Investigative Dermatology” 6 citations
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November 2018 in “American journal of transplantation” UV light helped human hair transplants survive in mice without broad immunosuppression.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers found that certain miRNAs, which affect immune system regulation, are differently expressed in mice with a hair loss condition compared to healthy mice.
January 2026 in “Metabolites” Obesity may weaken the immune system and increase cancer risk.
47 citations
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June 2013 in “Biology of blood and marrow transplantation” Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.
November 2024 in “medRxiv (Cold Spring Harbor Laboratory)” Genetic factors affecting skin health and body weight may increase the risk of dermatophytosis.
153 citations
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June 2015 in “GenomeBiology.com” The environment around the time of conception can change the VTRNA2-1 gene in a way that lasts for years and may affect disease risk.
12 citations
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August 2013 in “Journal of Dermatological Science” The MAGE3 hypothesis for alopecia areata did not lead to a significant breakthrough.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” The study suggests a link between varicella-zoster virus and segmental vitiligo, with evidence of the virus disrupting skin pigment cells.
28 citations
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December 2005 in “Oncogene” May 2017 in “The journal of immunology/The Journal of immunology” Patients with certain FoxN1 gene mutations have severe immune issues but normal skin and hair.
58 citations
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December 2020 in “Mayo Clinic Proceedings” The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.
1 citations
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March 2023 in “International journal of rheumatic diseases” Relatives of lupus patients show signs of immune system activity but not full-blown lupus.
April 2017 in “Journal of Dermatological Science” B cells can both help and hinder the body's defense against melanoma.
7 citations
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December 1981 in “International Journal of Dermatology” Understanding genes can help diagnose and treat skin color disorders.
Certain gene variations and different levels of BDNF and CRH hormones are linked to vitiligo.
17 citations
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July 1994 in “Journal of Dermatological Science” The cause of alopecia areata is likely a mix of genetics, immune system issues, and environmental factors, with more research needed to understand it fully.
12 citations
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March 2023 in “Frontiers in immunology” Atopic dermatitis increases the risk of some autoimmune diseases.