research Immune modulation of hair follicle regeneration
Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
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750-780 / 1000+ results research Compound Heterozygous Mutations in Forkhead Box N1 (FOXN1) Lead to a Severe Immunodeficiency but Normal Hair and Nail Development in Patients
Mutations in the FOXN1 gene cause severe immune issues but don't affect hair and nails.
research Systemic Autoimmune Diseases
The document concludes that systemic autoimmune diseases are complex, incurable, and require ongoing treatment and research.
research Immunologic Studies in Patients With Alopecia Areata
Alopecia areata may be caused by the immune system attacking hair follicles.
research Data from Elevated Cutaneous Smad Activation Associates with Enhanced Skin Tumor Susceptibility in Organ Transplant Recipients
Higher TGF-β signaling may increase skin cancer risk in organ transplant recipients.
research Live Imaging of the Skin Immune Responses
Live imaging helps us understand skin immune responses and develop treatments.
research Alopecia Areata in Aging C3H/HeJ Mice
Alopecia areata in these mice is inherited, more common in young females, and can be treated with triamcinolone acetonide.
research A Review on Unraveling the Complexity of Autoimmune Skin Disorders: Genetic Influences, Environmental Triggers and Innovative Management Approaches
Autoimmune skin disorders are caused by genetic and environmental factors and are treated with various medications and preventative strategies.
research 058 Subset analysis of NKG2D+ cells in peripheral blood mononuclear cells
The study suggests that a specific type of immune cell, memory-like NK cells, may increase during active hair loss in Alopecia areata.
research 006 Exogenous IL-27 promotes immunosuppressive T cells and prevents the development of alopecia areata in C3H/HeJ mice
IL-27 may help prevent hair loss in alopecia areata by promoting immunosuppressive T cells.
research LB1031 Immune Cell-Mediated Amplification of Stem Cell Activation in Hairy Melanocytic Nevus via Osteopontin-CD44 Axis
Immune cells boost stem cell activity in hairy moles, causing more hair growth.
research Meeting Report: 68th Montagna Symposium on the Biology of Skin “Decoding Complex Skin Diseases: Integrating Genetics, Genomics, and Disease Biology”
The symposium highlighted the importance of genetics in understanding and treating complex skin diseases.
research γδ T cells mediate a requisite portion of a wound healing response triggered by cutaneous poxvirus infection
γδ T cells are crucial for early wound healing after a skin virus infection.
research Postnatal determinants of testicular germ cell tumor by histological subtypes: The EPSAM1 and EPSAM2 studies
Childhood and adult height, and early immune-related hospitalizations increase testicular cancer risk, while baldness, larger families, and sports reduce it.
research Increased PHGDH expression uncouples hair follicle cycle progression and promotes inappropriate melanin accumulation
Increased PHGDH expression causes early melanin buildup in hair follicles.
research Association of mtDNA M/N haplogroups with systemic lupus erythematosus: a case-control study of Han Chinese women
The mtDNA N haplogroup is linked to a higher risk of late-onset lupus and specific symptoms in Han Chinese women.
research “Prick or treat”: a case of systemic reaction during intradermal tests with beta-lactams
Longer treatment with vismodegib lowers relapse risk in basal cell carcinoma.
research Genetic targeting of lymphatic endothelial cells in mice: current strategies and future perspectives
Mouse models help target specific genes in lymphatic cells for research.
research Immunohistochemical assessment of SOX10 and its relation to the immune cellular infiltrate in alopecia areata follicles
SOX10 in hair follicles is linked to inflammation in alopecia areata.
research Evaluating HWE and Association in Genome Wide Association Studies: A Unified Procedure
The new method improves SNP analysis in genetic studies by combining tests, enhancing accuracy and cost-effectiveness.
research 0150 Single-cell and spatial transcriptome profiling reveals innate-adaptive crosstalk in alopecia areata
research Two mouse mutations mapped to chromosome 11 with differing morphologies but similar progressive inflammatory alopecia
Two mouse mutations cause similar hair loss despite different skin changes.
research An immune regulatory CCT repeat containing oligodeoxynucleotide capable of causing hair loss in male mice
A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.
research IMMUNOTHERAPY OF CANCER: IMMUNE CHECKPOINT BLOCKERS, VACCINES AND ADOPTIVE T CELL THERAPIES
Enhancing immune response can improve cancer treatment effectiveness.
research IMMUNE-DRIVEN ACTIVATION OF HAIR FOLLICLE STEM CELLS AS A TRANSLATIONAL MODEL FOR FUTURE CELL-BASED THERAPY DEVELOPMENT
Immune activation of hair follicle stem cells can help develop new hair regeneration therapies.
research Phenotyping mice with skin, hair, or nail abnormalities: A systematic approach and methodologies from simple to complex
Understanding genetic variations in mice is crucial for studying skin, hair, or nail abnormalities.
research Profile of 513 patients with alopecia areata: associations of disease subtypes with atopy, autoimmune disease and positive family history
Certain types of alopecia areata are linked to allergies, autoimmune diseases, and family history.
research Molecular genetics of androgen insensitivity
Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.
research Immunological Skin Diseases
Immunological skin diseases in pigs are rare and can be caused by immune system issues or external factors.
research Editors' Picks
New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.