research 519 Phase I/IIa clinical trial for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes
The gene therapy showed significant wound healing and was safe for treating severe RDEB.
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870-900 / 1000+ resultsresearch Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming
Long-term skin biopsy cultures can produce many fibroblasts that remain functional and can be reprogrammed.
research Application of Topical Immunotherapy in the Treatment of Alopecia Areata: A Review and Update
Topical immunotherapy can treat alopecia areata, but its effectiveness varies and the exact mechanism is unclear.
research Comparative biology of tissue repair, regeneration and aging
The symposium concluded that understanding how different species repair tissue and how this changes with age can help advance regenerative medicine.
research A biopsy-sized 3D skin model with a perifollicular vascular plexus enables studying immune cell trafficking in the skin
A small 3D skin model helps study how immune cells move in the skin.
research 83 Transcriptomic meta-analysis and deconvolution approaches unveil cellular dynamics in scarring and non-scarring primary lymphocytic alopecias
research 224 Humoral immune response to COVID-19 vaccination in psoriasis patients on biologic therapy is impaired compared to healthy controls
Psoriasis patients on biologic therapy have a weaker immune response to COVID-19 vaccination than healthy people.
research Correspondence
A man's skin cancer improved and some of his hair grew back after treatment with a special light therapy and a medication.
research Global and exponential stabilization of a chemotactic alopecia areata model with signal-dependent diffusion and sensitivity
Reducing CD8+ T cell growth can stabilize alopecia areata.
research Successful hair regrowth in an acute diffuse form of alopecia areata during oral tacrolimus treatment in a patient with rheumatoid arthritis
Oral tacrolimus helped a rheumatoid arthritis patient regrow hair lost due to alopecia areata.
research Regulatory T-Cells: Potential Regulator of Tissue Repair and Regeneration
Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.
research Recurrent implantation failure: A comprehensive summary from etiology to treatment
Individualized treatment and support can help most couples with recurrent implantation failure achieve pregnancy.
research 1495 Dimethyl fumarate ameliorates delayed wound healing due to IL-36Ra deficiency through inhibition of NET formation and oxidative stress
Dimethyl fumarate speeds up wound healing in IL-36Ra deficient mice by reducing NET formation and oxidative stress.
research Reepithelialization of a Full-Thickness Burn from Stem Cells of Hair Follicles Micrografted into a Tissue-Engineered Dermal Template (Integra)
Hair follicle stem cells helped heal a severe scalp burn without needing traditional skin grafts.
research Stem cells of hair follicles micrografted into a tissue-engineered dermal template (Integra®)
The treatment successfully integrated hair follicles into a dermal template, showing new hair growth and blood vessel formation.
research The Simplest Protocol for Rapid and Long-Term Culture of Primary Epidermal Keratinocytes from Human and Mouse
A new method helps grow skin cells from humans and mice more easily and quickly.
research Rapidly Progressive Alopecia Universalis after Varicella-Zoster Virus Infection: The role of Immune Dysregulation and Tofacitinib treatment
Tofacitinib effectively regrows hair in alopecia universalis triggered by a virus.
research Decision letter: Stimulation of hair follicle stem cell proliferation through an IL-1 dependent activation of γδT-cells
IL-1 signaling is crucial for hair follicle stem cell growth and wound healing.
research High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata
CD8+ T cells are involved in alopecia areata and may cause disease relapse.
research Diverse cellular players orchestrate regeneration after wounding
Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.
research Repigmentation of Poliosis After Epithelial Grafting for Vitiligo
Epithelial grafting can effectively repigment white hair in vitiligo patients.
research An improved and rapid method to construct skin equivalents from human hair follicles and fibroblasts
Researchers created a quick, cost-effective way to make skin-like tissue from hair follicles and fibroblasts.
research M-CSF-stimulated myeloid cells can convert into epithelial cells to participate in re-epithelialization and hair follicle regeneration during skin wound healing
Myeloid cells can turn into skin and hair cells to help heal wounds.
research Directed Expression of a Chimeric Type II Keratin Partially Rescues Keratin 5-null Mice
A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.
research 231 Novel protocol for the invitro maintenance and expansion of adult epidermal LGR5+ stem cells
A new method helps grow skin stem cells better, which could improve skin grafts for burn victims.
research Vitiliginous lesions during contact immunotherapy for alopecia in a patient with autoimmune thyroiditis
Contact immunotherapy can cause vitiligo in patients with autoimmune conditions.
research The Anagen Hair Cycle Induces Systemic Immunosuppression of Contact Hypersensitivity in Mice
Hair growth phase in mice weakens certain immune responses.
research No evidence for the immunocompetence handicap hypothesis in male humans
Higher free testosterone levels in men are linked to a stronger immune response, not weaker.
research Preparation of highly-concentrated autologous platelet-rich plasma for biomedical use
A simple method was developed to prepare concentrated platelet-rich plasma for use in healing and tissue repair.
research Advances and applications of biomimetic biomaterials for endogenous skin regeneration
Biomimetic biomaterials can improve skin healing by mimicking natural tissue and reducing immune rejection.