266 citations
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January 2016 in “Development” YAP and TAZ are crucial for skin cell growth and repair.
188 citations
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February 2023 in “International Journal of Molecular Sciences” Flavonoids can help heal wounds effectively due to their beneficial properties.
122 citations
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April 2020 in “American Journal Of Pathology” Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
113 citations
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June 2019 in “F1000Research” Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
105 citations
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April 2014 in “Trends in Pharmacological Sciences” Targeting the Smoothened receptor shows promise for treating certain cancers.
87 citations
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March 2017 in “Journal of Clinical Investigation” PSENEN gene mutations can cause both Dowling-Degos disease and acne inversa.
70 citations
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June 2023 in “International Journal of Molecular Sciences” Air pollution harms skin health and can worsen skin diseases.
57 citations
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January 2020 in “International Journal of Molecular Sciences” PADs are crucial for healthy skin and hair, and their imbalance can cause skin and hair disorders.
51 citations
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March 2022 in “Frontiers in Immunology” Alarmin cytokines are key in controlling skin immunity and inflammation.
41 citations
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July 2019 in “Clinical Cosmetic and Investigational Dermatology” The skin's immune system helps it regenerate and fight infections.
38 citations
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November 2024 in “Scientific Reports” The new wound dressing speeds up healing and kills bacteria effectively.
38 citations
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February 2021 in “Journal of Investigative Dermatology” Aging slows wound healing due to weaker cells and immune response.
31 citations
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August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.
31 citations
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August 2015 in “Stem Cells Translational Medicine” Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.
29 citations
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March 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can help heal skin wounds in other diabetic mice.
20 citations
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August 2020 in “Scientific Reports” Low-dose bisphenol A increases prostate size in rats by affecting certain enzymes.
17 citations
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May 2025 in “MedComm” Organoid technology is improving personalized medicine by better predicting drug responses and treatments.
9 citations
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May 2025 in “Stem Cell Research & Therapy” Extracellular vesicles can both worsen and help treat age-related diseases and are useful for early diagnosis.
9 citations
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August 2022 in “Frontiers in Pharmacology” Kangfuxin (KFX) extract speeds up wound healing and improves skin regeneration.
8 citations
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February 2025 in “Pharmaceuticals” Polyphenols may help treat skin diseases due to their anti-inflammatory and antioxidant effects.
7 citations
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January 2023 in “Frontiers in Cell and Developmental Biology” Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.
7 citations
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December 2022 in “Frontiers in Bioengineering and Biotechnology” Extracellular vesicles show promise for wound healing, but more research is needed to improve their stability and production.
6 citations
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March 2024 in “Saudi Pharmaceutical Journal” The new delivery system could improve pain and inflammation relief in gout.
6 citations
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October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
6 citations
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January 2015 in “Journal of regenerative medicine & tissue engineering” The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
5 citations
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March 2022 in “Frontiers in Medicine” PRP is effective for treating hair loss, especially with other treatments.
5 citations
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February 2022 in “Stem cell reports” Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.
5 citations
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November 2021 in “Frontiers in Cell and Developmental Biology” Caffeine can damage hearing cells and affect hearing recovery after ear trauma.
4 citations
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August 2025 in “Molecules” Medicinal plants show promise for skin disorders but need more research for safe clinical use.
4 citations
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December 2024 in “Life” Recognizing race-specific skin traits is crucial in pediatric dermatology.